Schematic of experimental paradigms. by Shiva Farashahi (5018381)

“…Following the appearance of the fixation cross and information about the maximum reward (50 and 100 points), subjects were presented with a diminishing arc informing them about the rate of reward decrease on a given trial. …”

Silencing expression of Foxo1 increases Na_V1.5 expression. by Weike Mao (181121)

“…<p>Western blots showed decrease of Foxo1 protein by 50 MOI (n = 4) and 100 MOI Adv-Foxo1 RNAi (n = 4) increased Na_V1.5 protein in HL-1 cells in comparison with 100 MOI Adv-scramble RNAi (n = 4) (A) and this inhibition reached the significant difference (*p<0.05) at 100 MOI Adv-Foxo1-RNAi (C). …”

Greater volumes are required to reduce muscle performance in well-trained individuals by Filipe Dinato de Lima (5311142)

“…<div><p>Abstract A specific drop jumps (DJs) protocol (using 100 jumps) has been largely used to induce muscle damage. …”

Effects of variation in D1R-sensitivity on the WM-robustness in terms of potential barrier (PB). by Melissa Reneaux (833810)

“…<p>Increase in <i>D</i>1<i>R</i>_<i>sens</i> causes a consistent decrease in the PB of any individual level of sustained activity either sampled from the pre-peak (A) or from the post-peak (B) set of the modulation profile of cortical sustained <i>a</i>_<i>PN</i> activity. …”

Early blockade of CB1 and/or CB2 receptors reduces the density of serotonergic fibres below the lesion site. by Angel Arevalo-Martin (298990)

“…(E) Quantification of the area occupied by serotonin shows a significant decrease in AM630- and AM281/AM630-treated rats and a strong trend to decrease in AM281-treated rats, that is close to statistical significance (p = 0.06). …”

Effects of variation in D1R-sensitivity on the WM-robustness in terms of signal-to-noise ratio (SNR). by Melissa Reneaux (833810)

“…<p>Similar to the PB, increase in <i>D</i>1<i>R</i>_<i>sens</i> causes a consistent decrease in the SNR of any individual level of sustained activity either sampled from the pre-peak (A) or from the post-peak (B) set of the modulation profile of cortical sustained <i>a</i>_<i>PN</i> activity. …”

Imaging of Intracellular Tryptophan Levels with FLIPW-CTYT in COS-7 Cells by Thijs Kaper (34812)

“…<p>(A) Perfusion of COS-7 cells with various concentrations l-tryptophan (L-Trp) and 100 μM l-histidine (L-His) in Tyrode's buffer. …”

Effects of CTP on CoaE enzymatic activity. by Guneet Walia (258006)

“…<p>(A), Histogram depicting the percent decrease in CoaE activity in the presence of CTP, with the activity of CoaE in the presence of ATP (1 mM) and DCoA (0.5 mM) treated as 100% (Lane 1). …”

Modulation of human monocytes by exposure to mitochondrial DAMPs. by Irene Fernández-Ruiz (5653951)

“…<p>(<b>A</b>) Workflow diagram: MΦs from HV were pre-exposed to mitochondrial DAMPs (mtLys, 20 µg/ml, white bars), LPS (10 ng/ml, gray bars) or left untreated (black bars) for 5 days, then stimulated for 24 h with LPS, as described in the scheme; <b>B–F</b>: (<b>B</b>) Protein levels of IL1β, (<b>C</b>) IL6, (<b>D</b>) IL12p70, (<b>E</b>) TNFα and (<b>F</b>) TGF-β in culture supernatants (measured by CBA). …”

Glucose intolerance and acute insulin response (AIR) is improved with RU486 and C113176 treatment. by Jacqueline L. Beaudry (539019)

“…<p>Fasting (basal, 0 minutes) and stimulated blood glucose levels (mM) were measured at 5, 15, 30, 60, 90 and 120 minutes post oral glucose gavage (A). …”

Effects of p-ERK1/2 and p-p38MAPK inhibitors on TNFα-induced occludin expression in hCMEC/D3 cells. by Yawen Ni (3723304)

“…<p>(A) Initial testing for cell viability using WST-1 assay indicated toxicity of cells upon incubation (24h) with TNFα (10 ng/mL) in the presence of SB202190 at 10 μM but not at 2 μM. …”

Hierarchical agglomerative cluster analysis of expression patterns of <i>Danio rerio</i> embryos tothree whole sediments and sediment extracts and 11 substances. by Kerstin Bluhm (507637)

“…<p>(Yang et al. 2007; Acrylamide: 71 mg/l; Arsenic: arsenic (III) oxide, 79 mg/l; BDE: 2,2′4,4′-tetrabromo-diphenyl ether solution 47, 38.9 mg/l; CA: 4-chloroaniline, 50 mg/l; Cd: cadmium chloride, 5 mg/l; DDT: 1,1-bis-(4-chlorphenyl)-2,2,2-trichlorethane 15 mg/l; Lead: lead (II) chloride, 2.8 mg/l; PCB: Aroclor 1254, 33 mg/l; TBHQ: tert-butylhydroquinone, 1.7 mg/l; TCDD: 2,3,7,8-tetrachlorodibenzo-<i>p</i>-dioxin, 500 ng/l; VA: valproic acid, 50 mg/l). …”

Effect of age group and TBI on change in muscle thickness in critically-ill children. by Ryan W. Johnson (6103013)

Nicotine microperfusion impairs VOR gain adaptation. by Francesca Prestori (416977)

“…Based on the polarity of the waveform of Purkinje cell activity identified in each track, the location of the granule cell layer was determined, and a dye-labelled vehicle solution with or without 5–10 ng nicotine (n = 8 and n = 7, respectively) was injected. …”

Cytochrome C-oxidase and ATP-production. by Constanze Nossol (326870)

“…Furthermore, a significant decrease in the ATP-content was found in IPEC-J2 after the application of FCCP (p<0.001; IPEC-J2-FCCP: 3680 pmol/100 000 cells).…”

Supplementary file 1_Global burden and trends of adverse effects of medical treatment, 1990–2021: an analysis from the global burden of disease study 2021.docx by Keqing Zhang (326894)

“…By 2036, it is forecast that ASIR will decrease to 72.33 (19.40–125.27) per 100,000 persons-year, and ASDR will decrease to 40.98 (21.52–60.43) per 100,000 persons-year.…”

Image_8_Pharmacokinetic Behavior of Vincristine and Safety Following Intravenous Administration of Vincristine Sulfate Liposome Injection in Chinese Patients With Malignant Lymphom... by Fen Yang (287005)

“…VCR elimination from the circulation after injection of VSLI was characterized by a significantly increased maximum concentration (C_max, 86.6 ng/mL) and plasma area under the plasma concentration-time curve from zero to infinity (AUC_0-Inf, 222.1 ng/mL h), markedly decreased distribution volume (V_z, 224.1 L) and plasma clearance (CL, 8.9 L/h) compared to lower C_max (26.6 ng/mL) and AUC_0-Inf (95.1 ng/mL h), larger V_z (688.8 L) and CL (22.1 L/h) for VSI. …”

Image_1_Pharmacokinetic Behavior of Vincristine and Safety Following Intravenous Administration of Vincristine Sulfate Liposome Injection in Chinese Patients With Malignant Lymphom... by Fen Yang (287005)

“…VCR elimination from the circulation after injection of VSLI was characterized by a significantly increased maximum concentration (C_max, 86.6 ng/mL) and plasma area under the plasma concentration-time curve from zero to infinity (AUC_0-Inf, 222.1 ng/mL h), markedly decreased distribution volume (V_z, 224.1 L) and plasma clearance (CL, 8.9 L/h) compared to lower C_max (26.6 ng/mL) and AUC_0-Inf (95.1 ng/mL h), larger V_z (688.8 L) and CL (22.1 L/h) for VSI. …”

Image_6_Pharmacokinetic Behavior of Vincristine and Safety Following Intravenous Administration of Vincristine Sulfate Liposome Injection in Chinese Patients With Malignant Lymphom... by Fen Yang (287005)

“…VCR elimination from the circulation after injection of VSLI was characterized by a significantly increased maximum concentration (C_max, 86.6 ng/mL) and plasma area under the plasma concentration-time curve from zero to infinity (AUC_0-Inf, 222.1 ng/mL h), markedly decreased distribution volume (V_z, 224.1 L) and plasma clearance (CL, 8.9 L/h) compared to lower C_max (26.6 ng/mL) and AUC_0-Inf (95.1 ng/mL h), larger V_z (688.8 L) and CL (22.1 L/h) for VSI. …”

Image_7_Pharmacokinetic Behavior of Vincristine and Safety Following Intravenous Administration of Vincristine Sulfate Liposome Injection in Chinese Patients With Malignant Lymphom... by Fen Yang (287005)

“…VCR elimination from the circulation after injection of VSLI was characterized by a significantly increased maximum concentration (C_max, 86.6 ng/mL) and plasma area under the plasma concentration-time curve from zero to infinity (AUC_0-Inf, 222.1 ng/mL h), markedly decreased distribution volume (V_z, 224.1 L) and plasma clearance (CL, 8.9 L/h) compared to lower C_max (26.6 ng/mL) and AUC_0-Inf (95.1 ng/mL h), larger V_z (688.8 L) and CL (22.1 L/h) for VSI. …”