DZNep-mediated sensitization to TRAIL correlates with enhanced activation of caspase signaling and involvement of the mitochondrial apoptosis pathway. by Frank K. Braun (698401)

“…(<b>C</b>) Activation of the mitochondrial apoptosis pathway was determined by TMRM staining for mitochondrial membrane potential (Δψ_m) in Z-138 cells treated with DZNep (0.2, 1, 3, or 5 μM) alone for 40 h. (<b>D, E</b>) Analysis of Δψ_m of cells (Z-138, BJAB, and SU-DHL-9) treated with DZNep (1 μM, 24 h) followed by TRAIL (10 ng/ml for 1–5 h or 20 ng/ml for 16 h). …”

αII-Spectrin silencing changes invadosome morphologies. by Aurélie Ponceau (716023)

“…Knockdown of αII-spectrin induces a significant decrease in ring diameters due in particular to an increase in the percentage of rings with a small size and a decrease number of large rings. …”

Immunohistochemical examination of MPO in liver tissue. by Rasha E. Mostafa (11767721)

“…<p>Liver tissues, immunohistochemically stained with anti-MPO antibodies, from <b>(A)</b> sham-operated rats, <b>(B)</b> ovariectomy-control rats didn’t show notable expression of NF-KB in the liver tissue, <b>(C, D)</b> TAA-control rats showing a robust positive result of the stain all over the lobule, <b>(E)</b> rats treated with <i>panax ginseng</i> (100 mg/kg) showing a mild decrease in the positively stained cells, and <b>(F)</b> rats treated with <i>panax ginseng</i> (300 mg/kg) showing a remarkable decrease in the positive result <b>(MPO immunohistochemical staining)</b>.…”

Table1_Nanotechnology boosts the production of clean energy via nanoparticle addition in anaerobic digestion.DOCX by J. Cunha de Castro (18567382)

“…In addition, we observed that concentrations of nanoparticles higher than 100 mg/L can have adverse effects, with an overall decrease in biogas production. …”

Micromolar ZnCl₂ reduces the amplitude of the time-dependent current. by Monica Bregante (3391766)

“…<p>A) The decrease of a typical inward time-dependent current induced by the addition of 100 μM ZnCl₂ to the bath solution. …”

CyclinD1 transcriptional repression by T3 implicates thyroid hormone receptor α1 (TRα1) by Zahra Hassani (31174)

“…</p><p>© 2007 The Author(s)</p> () Quantification of TRα1 and TRα2 mRNAs in 3T3 cells transfected by 5–100 nM of siTRα1 (500 µl per well). The total amount of TRα1 and TRα2 mRNA in each condition was normalized to that of 36B4 (a control gene) in the same group. …”

Response of ERK phosphorylation to cetuximab treatment stratified <i>KRAS</i> mutants into two groups ex vivo. by Takahiro Tashiro (827031)

“…Upper panels: relative ATP content of reconstituted spheroids cultured with the indicated doses of cetuximab for 7 days. Mean±SD is shown. N = 3–6. Significance of the decrease in relative ATP content. …”

Lineage-Through-Time (LTT) plot of Hyalospheniidae. by Omar Fiz-Palacios (457505)

“…The number of lineages (x axis) is plotted against time (y axis) in such way that each increase on the number of lineages represents a cladogenesis (a node) in one of the 100 phylogetic trees. …”

<i>In vitro</i> T2* measurement of macrophages labeled with iron oxide. by Hye Rim Cho (188703)

“…(B) The T2* of the macrophages was found to decrease from 100±6.40 ms in the absence of FIONs. …”

Effect of myricetin on <i>P</i>. <i>gingivalis</i>-induced NF-κB activation using the U937-3xκB-LUC cell line model. by Daniel Grenier (522918)

“…<i>gingivalis</i> (ATCC 33277) at MOI of 100. A value of 100% was assigned to NF-κB activation induced by <i>P</i>. …”

Data_Sheet_1_Acclimation History of Elevated Temperature Reduces the Tolerance of Coralline Algae to Additional Acute Thermal Stress.PDF by Tessa M. Page (9016694)

“…Average relative change in O₂ produced resulted in a 100–175% decrease, with the largest decrease found in algae acclimated to the combined treatment of elevated temperature and reduced pH. …”

Impact of KCNE1 expression on WT Kv7.1 and mutant R228C. by Liora Shamgar (44235)

“…(D) Representative traces of R228C+WT KCNE1 channels, when oocytes were bathed with ND96 containing 100 µM Cu-Phen. Currents were evoked by a train of step depolarization to +30 mV. …”

Effects of mifepristone and the Porsolt test on the survival of 1 week-old cells. by María Llorens-Martín (194343)

“…<p><b>A</b> Mifepristone prevented the decrease in the number of 1 week-old IdU⁺ cells induced by exposure to the Porsolt test (interaction p = 0.005). …”

Histological sections and Mankin score of rabbit cartilages also showed OA change at 2 weeks. by Kohei Nishitani (526108)

“…<p>A) OA change such as fibrillation of the surface and decrease of safranin/O stainingwas detected from 2 weeks and deteriorated overtime. …”

Effect of IL-12 and IL-18 on rheumatoid arthritis synovium cells by Masanori Kawashima (3349)

“…</p> Rheumatoid arthritis synovium cells (1 × 10/ml in RPMI 1640 medium with 10% fetal calf serum) were cultured in triplicate for 7 days with or without 1 ng/ml of IL-12, 5 ng/ml of IL-18, 2 μg/ml of IL-18 binding protein (IL-18BP), or a combination of these. …”

The number of infiltrated ANGPTL2-positive macrophages increases in ischemic brain. by Toshihiro Amadatsu (3352955)

“…After ligation of the right common carotid artery (CCAO), we observed a 40% drop in CBF. MCA occlusion promoted a further decrease to less than 80–90% of baseline CBF. …”

Figure 6 by Akihiro Horii (24061)

“…There is an increase in proliferation following the increase PRG % scaffold when increased from 0 to 40%. There was a decrease in cell proliferation at PRG 100% suggesting that there is an optimal ratio of PRG and RADA16 scaffolds.…”

Effects of telomestatin on Topo III signals and Topo III/TRF2/BLM protein levels in MRC5-V1/YFP-Topo III cells. by Nassima Temime-Smaali (260017)

“…Dapi staining of DNA is shown in blue. Telomestatin induced a decrease of Topo III foci number and intensity. …”

Antihyperglycemic and neuroprotective effects of Wattakaka volubilis (L.f.) Stapf root against streptozotocin induced diabetes by Hajira Banu Haroon (12847493)

“…All the alcohol extract treated animals, showed a significant decrease in serum glucose level (P<0.001), and overall decrease in the severity of diabetic neuropathy. …”

Response of the insulin signaling network to the Akt inhibitor UCN-01 in L6 cells. by Alessandro Bertuzzi (379953)

“…<p><b>(A- C)</b> Model predictions of , and at 1 and 100 nM insulin in control (white boxes) and in cells exposed to UCN-01 (black boxes), obtained by a tenfold decrease of the PDK1 parameter <i>a</i>₉. …”