Image 2_Atractylenolide-I restore intestinal barrier function by targeting the S100A9/AMPK/mTOR signaling pathway.tif by Chen Chen (6544)

“…Mechanistically, recombinant human S100A9 protein was found to induce a decrease in intracellular Ca²⁺ concentration, while AT-1 regulated the expression of tight junction proteins via modulation of the AMPK/mTOR signaling pathway. …”

Image 1_Atractylenolide-I restore intestinal barrier function by targeting the S100A9/AMPK/mTOR signaling pathway.tif by Chen Chen (6544)

“…Mechanistically, recombinant human S100A9 protein was found to induce a decrease in intracellular Ca²⁺ concentration, while AT-1 regulated the expression of tight junction proteins via modulation of the AMPK/mTOR signaling pathway. …”

Decreased production of IL-12p70 and IL-23 in response to LPS+R848 stimulation in frail old individuals. by Nathalie Compté (418458)

Posterior mean year-stage detection probabilities (red circles) and 95% Bayesian Credible Intervals (BCI; vertical black lines) of the (A) ≤100 m radius, and (B) infinite radius da... by Taza D. Schaming (8911517)

Quantifications of SEMG1-2 combined with measurements of CpG methylation levels in the Svs2 and Svs3ab promoters. by Ludwig Stenz (779897)

“…(B) CpG methylation levels in both Svs2 and Svs3ab promoters were validated using a pre-mixed calibration standard (0, 5, 10, 25, 50, 75 and 100% Fig 5B and then measured in sperm-extracted DNA under each experimental conditions using bisulfite pyrosequencing in quintuplicates. …”

Strain-dependent alterations of fertility parameters in male offspring exposed in utero to DEHP. by Ludwig Stenz (779897)

“…Injections of 20 μl of 1.15 M DEHP diluted in corn oil corresponding to 300 mg/kg/day (D300) for 30 g mice estimates were compared with injections of 20 μl of corn oil as a vehicle for a fat-soluble compound, settled as the control condition (CTL). …”

Experimental outline. by Melissa A. MacIver (12850566)

S100A9: A Potential Biomarker for the Progression of Non-Alcoholic Fatty Liver Disease and the Diagnosis of Non-Alcoholic Steatohepatitis by Xiaolin Liu (403100)

“…We find that gene expression of s100a9 was higher in NAFL group compared with control, and was increased in NASH groups and decreased in NAFL + T2DM group compared with NAFL. …”

Microarray analysis of genes modulated by siRNA treatments. by Giorgia Urbinati (554921)

Susceptibility to COPD: Differential Proteomic Profiling after Acute Smoking by Lorenza Franciosi (600602)

“…SerpinB3 and Uteroglobin decreased after acute smoke exposure in young non-susceptible individuals exclusively, whereas Peroxiredoxin I, S100A9, S100A8, ALDH3A1 (Aldehyde dehydrogenase 3A1) decreased both in young susceptible and non-susceptible individuals, changes being significantly different between groups for Uteroglobin with iTRAQ and for Serpin B3 with iTRAQ and ELISA measures. …”

D452A, E464A, E470A, and E475A mutations decreased the calcium sensitivity. by Qinghuan Xiao (573411)

The biphasic effect of emodepside on hum KCNMA1 currents. by Anna Crisford (803573)

“…Data points are the mean ± s.e.mean. 100nM emodepside had a biphasic effect on hum KCNMA1 currents eliciting a significant increase between 4 and 8 min application (p<0.05) and a significant decrease after 20 min application (p<0.001); two-way ANOVA with Bonferroni post-hoc tests.…”

<i>In vitro</i> and <i>in vivo</i> anti-inflammatory active copper(II)-lawsone complexes by Ján Vančo (490366)

“…In addition, a strong intracellular pro-oxidative effect of all the complexes has been found at 100 nM dose <i>in vitro</i>. …”

Overall survival (OS) of patient with newly diagnosed AML in South Korea, from 2011 to2020 by subpopulation: (a) Overall population, (b) OS by Age group, (c) OS by Treatment, (d) O... by Hyun Jin Han (18592254)

Effect of H₂O₂ on caveolae isolated through flotation gradient and identification of caveolae in C₂C₁₂ myoblasts. by Alexis Mougeolle (709121)

Intensity-modulated proton therapy decreases dose to organs at risk in low-grade glioma patients: results of a multicentric <i>in silico</i> ROCOCO trial by Daniëlle B. P. Eekers (5560430)

TGFβ1 expression was increased, and RASAL1 expression was decreased in NTM cells in response to a hypoxic environment. by Fiona McDonnell (2636635)

“…A 0hr Control was set to 100%, and the normoxic and hypoxic results were presented as a percentage of this; Normoxic = 95.5%, Hypoxic = 159.4% (P<0.01). n = 3 *P<0.05, **P<0.01. …”

Decrease in proliferation after ENU-exposure as decrease in BrdU immunostaining. by Vivian Capilla-Gonzalez (336046)

“…<p>Micrograph of the BrdU+ cells immunolabeled with DAB showed a decrease in the proliferation in the SVZ (B) and DG (D) of treated animals, compared with control group (A and C, respectively). …”

Global number of meningitis deaths by etiology and age group in 1990(A) and 2021(B). by Jun Li (6494)

cMSC/Collagen Type I gel fabrication. by Melissa A. MacIver (12850566)