An osprey nest with a large chick and an unhatched egg (photo P. Saurola). by Matti Viluksela (321291)

Loss of Diva decreases cell number and viability. by Nicole Suyun Liu (311271)

Azurin decreases P-cadherin protein levels. by Nuno Bernardes (435240)

Blood meal decreases ROS levels in the midgut. by Jose Henrique M. Oliveira (150471)

Release-decreasing vs. release-increasing astrocytes. by Maurizio De Pittà (194237)

“…The nature of the change depends on the nature of presynaptic receptors. (<b>A</b>) For α = 0, the effect of the astrocytic glutamate is a global decrease of synaptic release, which fades away slowly from its onset at rate Ω_G (<i>green area</i>). …”

Microglia-conditioned medium decreases NPC viability. by Johanna Mäkelä (223358)

GKA23 decreases hepatic glucose production. by Min Lu (238723)

DataSheet_1_Transcriptional Profiling and Functional Analysis of N1/N2 Neutrophils Reveal an Immunomodulatory Effect of S100A9-Blockade on the Pro-Inflammatory N1 Subpopulation.doc... by Andreea C. Mihaila (11252988)

“…S100A9 inhibition with a specific small-molecule blocker, reduced CCL2, CCL3 and CCL5 chemokine expression and decreased MPO and MMP-9 activity, by interfering with the NF-kB signaling pathway. …”

Modafinil decreased EEG amplitude in the synchronized model. by Chang-Rui Chen (467755)

Regenerating axons are increased by ATRA and decreased by clodronate. by Valeria De La Rosa-Reyes (6658613)

“…(E) ATRA and clodronate liposome treatment, composite from 2 sections. Scale bar: 100 μm in A and B. (F) Bar and scatter plots of the number of axons per transverse section, sampled at approximately 200 μm distal to the cut site, showing mean ± SEM. …”

Increase of mitochondrial dysfunction and glycolysis by decreased NEFH. by Myoung Sook Kim (91321)

Matrix crosslinking decreases cell migration persistence. by Michael Pamonag (12295175)

Recombinant 3xK-C100Flag monomer increased longer Aβ peptides. by Joo In Jung (650746)

“…Molecular mass (m/z) of monomeric 3xK-C100Flag for Aβ40 is 4588.43 (calculated m/z: 4589.27), for Aβ42 is 4773.07 (calculated m/z: 4773.51), and for Aβ45 is 5084.52 (calculated m/z: 5086.90). 3xK-C100Flag dimer and trimer showed decreased Aβ levels compared to the monomer. …”

MicroRNA-138 Regulates Hypoxia-Induced Endothelial Cell Dysfunction By Targeting S100A1 by Anagha Sen (482673)

“…Bioinformatic analysis suggested that microRNA -138 (MiR-138) could target the 3′UTR of S100A1. Patients with critical limb ischemia (CLI) or mice subjected to femoral artery resection (FAR) displayed increased MiR-138 levels and decreased S100A1 protein expression. …”

Purified recombinant WT-C100Flag dimer and trimer showed reduced Aβ production. by Joo In Jung (650746)

“…<p>(A) The purified recombinant WT-C100Flag monomer, dimer, and trimer eluates were loaded on a SDS-PAGE gel. …”

GluN2A(D731N) reduces the agonist potency. by Kai Gao (120150)

“…(<b>C,E</b>) The composite glutamate (in the presence of 100 μM glycine) concentration-response curves reveal a significant decrease in glutamate potency in both di-heteromeric (<b>C</b>) and tri-heteromeric (<b>E</b>) GluN2A(D731N)-containing NMDARs compared to wild type receptors. …”

The substitution F447L is adaptive for J4_S52-HVR1, while it decreases infectivity of parental J4 and J4_ΔHVR1 HCVcc. by Christina Holmboe Olesen (11154333)

Table_2_PE_PGRS31-S100A9 Interaction Promotes Mycobacterial Survival in Macrophages Through the Regulation of NF-κB-TNF-α Signaling and Arachidonic Acid Metabolism.docx by Sheng Liu (279488)

“…Our results revealed that M. tb Rv1768 promotes mycobacterial survival in macrophages by regulating NF-κB-TNF-α signaling and arachidonic acid metabolism via S100A9. Disturbing the interaction between Rv1768 and S100A9 may be a potential therapeutic target for tuberculosis.…”

Image_4_PE_PGRS31-S100A9 Interaction Promotes Mycobacterial Survival in Macrophages Through the Regulation of NF-κB-TNF-α Signaling and Arachidonic Acid Metabolism.TIF by Sheng Liu (279488)

“…Our results revealed that M. tb Rv1768 promotes mycobacterial survival in macrophages by regulating NF-κB-TNF-α signaling and arachidonic acid metabolism via S100A9. Disturbing the interaction between Rv1768 and S100A9 may be a potential therapeutic target for tuberculosis.…”

Table_1_PE_PGRS31-S100A9 Interaction Promotes Mycobacterial Survival in Macrophages Through the Regulation of NF-κB-TNF-α Signaling and Arachidonic Acid Metabolism.docx by Sheng Liu (279488)

“…Our results revealed that M. tb Rv1768 promotes mycobacterial survival in macrophages by regulating NF-κB-TNF-α signaling and arachidonic acid metabolism via S100A9. Disturbing the interaction between Rv1768 and S100A9 may be a potential therapeutic target for tuberculosis.…”