HDAC and Proteasome Inhibitors Synergize to Activate Pro-Apoptotic Factors in Synovial Sarcoma by Aimée N. Laporte (3617987)

Subjects:

High-throughput drug screen reveals HDAC and proteasome inhibitors as potent drug classes against synovial sarcoma. by Aimée N. Laporte (3617987)

Subjects:

HDAC and proteasome inhibition leads to apoptosis via pro-apoptosis protein activation, ROS production and caspase activation. by Aimée N. Laporte (3617987)

Subjects:

Overexpression of wild-type and mutant ALDH3A1 retards hTCEpi cell proliferation. by Vindhya Koppaka (845151)

“…After 4 d, cells were trypsinized and viable cells were counted using trypan blue exclusion on a hemocytometer. Consecutively, 2.0 x 10⁵ cells were transferred to a new dish and this process repeated for a total of 8 passages, i.e., for 32 d until treated cells showed decreasing cell numbers. …”

The top 100 TCs with highest RR for all-cause, CVDs, and RDs mortality. by Wenzhong Huang (538470)

Effect of 1N11 on cultured endothelial cell migration impairment by 3F8 or aPL, and on aPL blunting of carotid artery reendothelialization in vivo. by Chieko Mineo (725831)

Expression of coilin decreases neurite outgrowth. by Benjamin Förthmann (498522)

“…For statistical evaluation, averaged relative neurite lengths of n>100 cells were compared, pooled from three individual experiments (means ± SEM; n.s.; A: **, p<0.01; Mann-Whitney test; B: n.s., non-significant; *, p<0.05; **, p<0.01; ***, p<0.001; Dunn’s test for comparison of multiple groups).…”

Heatmaps from relative expression of miRNAs, using as a metric the euclidean distance calculated between each PC bag and storage periods for hierarchical cluster construction. by Thaís Brilhante Pontes (762387)

“…(A) A sample of the relative expression of 100 PC bags were hierarchically clustered and scored as statistically significant p <0.001 for six periods of storage, showing that miR-127, was shown to be down-regulated in most PC bags experimentally validated. …”

Impairment of PFC decreases learning performance. by William H. Barnett (14822620)

GSK343 decreased tumor stemness. by Laura V. Bownes (10276762)

“…Treatment with GSK343 significantly decreased tumorsphere formation by both the COA3 (A) and COA6 (B) cells, representing a decrease in stem cell-like phenotype. …”

MVK activates microglia and decreases phagocytosis. by Ren Y. Sato (16914027)

Fungal infection decreases cell proliferation. by Mariem Ben-Abdallah (181235)

Tetrandrine decreases Mtb antigen presentation. by Elham Karamooz (2584474)

(R)-Albuterol decreases pulmonary inflammation after OVA sensitization and aerosol challenge by Marcela A Ferrada (41716)

“…</p><p></p> On the first day of OVA challenge (day 14, see Methods) a miniosmotic pump (Alzet) containing (R)- or (S)- albuterol was inserted subcutaneously (200 μg/100 μl) and delivered a constant dose of 1 mg/kg/day (25 μl/day). …”

DJA2 decreases maturation of CFTR. by Patrick Kim Chiaw (7224539)

Conditional stabilization of β-catenin decreases frequency of Tbr2-expressing cells. by Christopher A. Mutch (243132)

“…This analysis also resulted in a markedly decreased Tbr2+ intermediate progenitor population in cortices (<b>F</b>) when compared to NesCre- control. …”

Eliminations of dorsal projections in DOM and DOM-A downregulation were due to reduced number of sLNvs and decrease of PDF. by Zhenxing Liu (399809)

Table_1_High Migration and Invasion Ability of PGCCs and Their Daughter Cells Associated With the Nuclear Localization of S100A10 Modified by SUMOylation.DOCX by Qi Zhao (124612)

“…After SUMO1 was inhibited, the nuclear S100A10 in PGCCs and daughter cells decreased, and their proliferation and migration abilities significantly decreased. …”

Table_6_High Migration and Invasion Ability of PGCCs and Their Daughter Cells Associated With the Nuclear Localization of S100A10 Modified by SUMOylation.DOCX by Qi Zhao (124612)

“…After SUMO1 was inhibited, the nuclear S100A10 in PGCCs and daughter cells decreased, and their proliferation and migration abilities significantly decreased. …”

Table_5_High Migration and Invasion Ability of PGCCs and Their Daughter Cells Associated With the Nuclear Localization of S100A10 Modified by SUMOylation.DOCX by Qi Zhao (124612)

“…After SUMO1 was inhibited, the nuclear S100A10 in PGCCs and daughter cells decreased, and their proliferation and migration abilities significantly decreased. …”