QD-BDNF probes activate TrkB signaling and induce neuronal survival. by Anke Vermehren-Schmaedick (551619)

“…(C) QD-BDNF-dependent survival is TrkB specific as pre-block with anti-TrkB receptors and subsequent QD-BDNF treatment decreased NG neurons survival (ANOVA, p<0.0001, Dunnett's post-hoc test, n = 5). …”

Rosiglitazone inhibited TGF-β1-induced collagen type I expression in ADPKD cyst-lining epithelial cells through PPARγ. by Yawei Liu (171534)

“…Then cells were pretreated with 10 µmol/L rosiglitazone for 1 h and incubated with TGF-β1 (5 ng/mL) for 24 h. (B) Cells were transfected with a PPARγ siRNA for 48 h, then pretreated with 10 µmol/L rosiglitazone for 1 h and incubated with TGF-β1(5 ng/mL) for 24 h. …”

Chp function is required for epibolic movements. by Hwee Goon Tay (250690)

“…Co-injection of 25 pg Chp mRNA with 5 ng Chp MO1/2 efficiently reduced the number of yolk plug defects at 8 hpf. …”

Diploid sexual populations evolve mutational robustness at lower mutation rate. by Kerry J. Kim (266640)

“…<p>Plots show results of 38 simulations to 5,000 generations with μ = 0.005, smoothed with a sliding window of 100 generations. (A) Robustness to point mutations shows diploid sexual populations evolve greater robustness, while diploid asexual populations have a transient decrease in robustness. …”

TNFα promotes proliferation of human synovial MSCs while maintaining chondrogenic potential by Mikio Shioda (4033967)

“…The expressions of 12 surface antigens were also examined in 3 donors.2.5 ng/ml and higher concentration of TNFα significantly increased cell number/dish and cell number/colony in both donors. …”

The catalytic activity of IP₃ 3-KA opposes NGF-driven neurite outgrowth from PC12 cells. by Richard Eva (331788)

“…IP₃ 3-KA 66-459-GFP expression results in a decrease in both indices of neurite outgrowth. …”

Phenotypic enfuvirtide resistance of full Env and HR1–HR2 recombinant viruses. by Franky Baatz (214467)

“…<p>U87.CD4.CCR5 and U87.CD4.CXCR4 were infected with HR1–HR2 and full Env recombinant viruses in the presence of decreasing concentrations of enfuvirtide, ranging from 15×10³ ng/ml to 0.04 ng/ml). …”

Time since the Population Collapse by Benoît Goossens (5103)

“…The thin and thick lines correspond to S1 and S2, respectively. The prior is shown as a dashed line, its median being 100,000 y ago (see text). …”

Apical CCP maturation is enhanced in PIP5KIβ-overexpressing cells. by Christina M. Szalinski (102971)

“…Scale bar: 100 nm. (B) Analysis of data from 33 control cells and 35 PIP5KIβ-overexpressing cells shows a decrease in the frequency of type III CCPs upon overexpression of PIP5KIβ.…”

Reduction in TB incidence and mortality achievable from shorter-course regimens over time. by Mariam O. Fofana (562254)

“…<p>Assuming TB incidence of 125 per 100,000/year, and 7% overall treatment default, the implementation of a four-month regimen vs. a six-month regimen results in a 1.9% reduction in incidence at 10 years (vertical line marks year 10 after introduction of a new regimen). …”

Biomass-diversity relationship. by Andrea S. Downing (131132)

“…The total biomass made up by 100 species decreases with increasing interspecific competition strength (left hand panel). …”

Capillary density. by Yeong-Hoon Choi (286493)

“…<p>A) Representative micrographs of left ventricular cross-sections (6 µm thickness) showing capillary vessels in all groups (as visualized by FITC-labeled lectin, scale bar represents 100 µm). …”

Effects of PP on the proliferation of liver cancer cell lines. by Wenwen Xu (175846)

“…<p><b>A.</b> MTT assay was taken to evaluate the liver cancer cell (Huh7, Hep3B, HepG2 and SMMC-7721) viability after the treatment with different concentrations of PP (0, 25, 50, 100, 200 or 400 µg/ml respectively) for up to 96 hr. …”

Bufalin exerted potent anti-osteosarcoma activity <i>in vitro</i>. by Xian-biao Xie (302694)

“…<p>(A) Bufalin induced a dose- and time-dependent decrease in osteosarcoma cell growth. …”

Supplementary Table 1 - Additional PSD Results by David Aguilar (7148330)

“…Summary of Additional Power Spectral Density Differences during Recovery Sleep. </b>Arrows represent a significant increase (↑) or decrease (↓) in normalized mGluR5 KO spectral power compared to WT controls in the same condition. …”

Immunohistochemistry of Adult OC1 Knockout Retinas. by Jillian J. Goetz (644028)

“…However, anti-Calb28k-staining shows a decrease in horizontal cells in OC1-KO retinas as compared to a wildtype littermate (F,F'). …”

Antiprotease activity of HE-4 at different concentration and at different condition against various serine, cystine and aspartic proteases. by Nirmal Chhikara (124762)

“…<p>(<b>A</b>) Percentage inhibition of various proteases like: trypsin, chymottrypsin, PSA, proteinase K, pepsin and papain by HE-4. …”

Application of Circulating Tumor DNA as a Non-Invasive Tool for Monitoring the Progression of Colorectal Cancer by Jiaolin Zhou (3147249)

“…The tumor loads appeared a sudden decrease upon surgery or other adjuvant treatments and then generally maintained at low levels (0.092ng/mL) until disease recurred. ctDNA increased by 13-fold when disease relapsed in one patient while the CEA and CA 19–9 levels remained normal. …”

Figure S4 from Exome Sequencing of Plasma DNA Portrays the Mutation Landscape of Colorectal Cancer and Discovers Mutated VEGFR2 Receptors as Modulators of Antiangiogenic Therapies by Rodrigo A. Toledo (14996709)

Associations among Erythroferrone and Biomarkers of Erythropoiesis and Iron Metabolism, and Treatment with Long-Term Erythropoiesis-Stimulating Agents in Patients on Hemodialysis by Hirokazu Honda (2964768)

“…Twenty patients who were injected with either CERA (N = 10) or DA (N = 10) at the end of the dialysis week (day 0), who had ferritin ≥ 100 ng/mL and/or transferrin saturation ≥ 20%, and hemoglobin > 9 g/dL were selected from among the 59 patients. …”