Global assessment of methylation levels and confounders contributing to hypomethylation in common CNV regions. by Corey T. Watson (250356)

“…Each plot shows a 100 bp moving average. Although a small decrease in methylation level is evident within CNVs compared to flanking regions, overall mean methylation levels within CNV regions (69%) are very similar to the genome average (70%). …”

RANKL and RANK Protects Mouse Podocytes from Apoptosis. by Shuangxin Liu (314178)

“…(J) Exogenous RANKL protected podocytes from PA induction apoptosis. RANKL (40 ng/ml) decreased PA-induced apoptosis (15.5±2.2%). …”

Table 1_Trends in the burden of urolithiasis in China: an analysis from the global burden of disease study 2021.xlsx by Yangyang Lin (3797422)

“…</p>Result<p>The age-standardised prevalence rate of urolithiasis in China has decreased from 96.23 per 100,000 in 1992 to 50.78 per 100,000 in 2021 for males and from 34.44 per 100,000 in 1992 to 22.04 per 100,000 in 2021 for females. …”

Regulation of HBV replication by agarose gel analysis in cells treated with miRNA. by Sun O. Park (319202)

“…<p>For these studies, 2.2.15 cells were transfected with miRNA mimics or miRNA antagonists followed by administration to transduced cells of either 20 ng/ml TGF-β or 100 µM iron for 48 h. (A) Changes in iron-treated cells are shown after expression of miR-125a-5p or -151-5p mimics. …”

Cell death delay sensitivity to the change in ProCasp6 concentration and Casp3 degradation kinetics in the clustering scenario. by Anna Matveeva (7430492)

“…<p>(A) Dramatic increase in the cell death delay upon the increased Casp3 degradation rate constant (kcat) by XIAP mediated ubiquitination which is a function of proteasomal protein degradation capacity as well as Casp3 self-cleavage for the cells stimulated with lower DL doses (5, 7.5 ng/mL). (B) High sensitivity to the minor decrease in XIAP concentration from its mean estimated concentration in HeLa cell 63 nM will lead to dramatic decrease in cell death delay for the cells stimulated with lower DL doses.…”

Characterization of the hESC differentiation model. by Sri Kripa Balakrishnan (71670)

“…<p>A. 10X Phase contrast images of H9 pluripotent hESCs and H9 hESCs induced to differentiate with BMP4 for 5 days. 200 ng/ml BMP4 in TeSR was used in all panels. …”

Results of morpholino knockdown and RNA rescue experiments by Brian E. Walter (47936)

“…Note the smaller size of the eye and severe reduction in the ventral region of the optic cup, denoted by the arrow in . : The corresponding fluorescence image shows the distribution of the lissamine-tagged morpholino for the embryo shown in . -: The typical result is observed following the co-injection of 4.5 ng morpholino and 1000 pg synthetic altPsf2 RNA. : The normal control, uninjected side of the embryo shown in - is displayed. : Normal morphological development is observed following the co-injection of Psf2MO (equivalent to 4.5 ng/blastomere at the eight-cell stage) and 1000 pg rescue RNA (altPsf2 RNA). : The corresponding fluorescence image to that shown in shows the distribution of the lissamine-tagged morpholino. -: Typical severe eye defect is observed following unilateral injection of lissamine-tagged Psf2MO into single blastomeres at the two-cell and four-cell stages (equivalent to 6 ng/blastomere at the eight-cell stage). : The normal control, uninjected side of the embryo shown in and is shown. : The typical severe eye defect phenotype is displayed following Psf2MO injection. …”

Discovery of Dramatically Improved Ammonia Synthesis Catalysts through Hierarchical High-Throughput Catalyst Screening of the Fe(211) Surface by Jon Fuller (6919253)

“…At 673 K and 20 atm, we find a decrease, δ­(Δ<i>G</i>^∫) = −0.19 eV, in the overall reaction free-energy barrier for the Co-doped case. …”

Discovery of Dramatically Improved Ammonia Synthesis Catalysts through Hierarchical High-Throughput Catalyst Screening of the Fe(211) Surface by Jon Fuller (6919253)

“…At 673 K and 20 atm, we find a decrease, δ­(Δ<i>G</i>^∫) = −0.19 eV, in the overall reaction free-energy barrier for the Co-doped case. …”

Data_Sheet_1_Nitrogen Source Matters: High NH4/NO3 Ratio Reduces Cannabinoids, Terpenoids, and Yield in Medical Cannabis.pdf by Avia Saloner (12705275)

“…To evaluate the hypothesis we examined the impact of five supply ratios of NH₄/NO₃ (0, 10, 30, 50, and 100% N-NH₄⁺, under a uniform level of 200 mg L^–1 N) on plant response. …”

Table 1_Global patterns and health impact of unintentional injuries among children and adolescents, 1990–2021.docx by Wei Wei (21173)

“…</p>Findings<p>Globally, in 2021, unintentional injuries in children and adolescents resulted in 157,808,979 cases (95% UI: 138,280,367–179,472,942), 305,596 deaths (95% UI: 240,004–365,146), and 28,410,167 DALYs (95% UI: 23,100,433–33,513,238). Among the five socio-demographic index (SDI) regions, the low-middle SDI region exhibited the most significant decrease in injury incidence. …”

Table 3_Global patterns and health impact of unintentional injuries among children and adolescents, 1990–2021.docx by Wei Wei (21173)

“…</p>Findings<p>Globally, in 2021, unintentional injuries in children and adolescents resulted in 157,808,979 cases (95% UI: 138,280,367–179,472,942), 305,596 deaths (95% UI: 240,004–365,146), and 28,410,167 DALYs (95% UI: 23,100,433–33,513,238). Among the five socio-demographic index (SDI) regions, the low-middle SDI region exhibited the most significant decrease in injury incidence. …”

Image 1_Global patterns and health impact of unintentional injuries among children and adolescents, 1990–2021.tif by Wei Wei (21173)

“…</p>Findings<p>Globally, in 2021, unintentional injuries in children and adolescents resulted in 157,808,979 cases (95% UI: 138,280,367–179,472,942), 305,596 deaths (95% UI: 240,004–365,146), and 28,410,167 DALYs (95% UI: 23,100,433–33,513,238). Among the five socio-demographic index (SDI) regions, the low-middle SDI region exhibited the most significant decrease in injury incidence. …”

Table 1_Global, regional, and national epidemiology and risk factors of geriatric digestive system cancers from 1990 to 2021.docx by Congcong Xu (3135876)

“…</p>Results<p>Globally, the incidence of GDSC increased from 1,876,969 [age-standardized incidence rate (ASIR) 405.48/100,000] in 1990 to 3,854,209 (ASIR 360.89/100,000) in 2021, with a slight decrease in ASIR [−0.57% average annual percentage change (AAPC)]. …”

Table 2_Global patterns and health impact of unintentional injuries among children and adolescents, 1990–2021.docx by Wei Wei (21173)

“…</p>Findings<p>Globally, in 2021, unintentional injuries in children and adolescents resulted in 157,808,979 cases (95% UI: 138,280,367–179,472,942), 305,596 deaths (95% UI: 240,004–365,146), and 28,410,167 DALYs (95% UI: 23,100,433–33,513,238). Among the five socio-demographic index (SDI) regions, the low-middle SDI region exhibited the most significant decrease in injury incidence. …”

Table 4_Global patterns and health impact of unintentional injuries among children and adolescents, 1990–2021.docx by Wei Wei (21173)

“…</p>Findings<p>Globally, in 2021, unintentional injuries in children and adolescents resulted in 157,808,979 cases (95% UI: 138,280,367–179,472,942), 305,596 deaths (95% UI: 240,004–365,146), and 28,410,167 DALYs (95% UI: 23,100,433–33,513,238). Among the five socio-demographic index (SDI) regions, the low-middle SDI region exhibited the most significant decrease in injury incidence. …”

Ras Tyrosine 4 is important for Ras ubiquitination. by Chalita Washington (8997378)

“…Reproducibly, we see decreased ubiquitination for Ras^Y4A and Ras^V7A mutants (red boxes). …”

Table_1_The Effect of Early Life Exposure to Triclosan on Thyroid Follicles and Hormone Levels in Zebrafish.docx by Ning Tang (138218)

“…Exposure to TCS from 3 to 300 ng/mL reduced the thyroid hormones production. The mean TT₃ and FT₃ levels of zebrafish decreased in 300 ng/mL TCS at 14 dpf (300 ng/mL TCS vs. control : TT₃ , 0.19 ± 0.08 vs. 0.39 ± 0.06; FT₃, 19.21 ± 3.13 vs. 28.53 ± 1.98 pg/mg), and the FT₄ decreased at 120 dpf ( 0.09 ± 0.04 vs. 0.20 ± 0.14 pg/mg). …”

DataSheet1_Investigation of Chromosomal Structural Abnormalities in Patients With Undiagnosed Neurodevelopmental Disorders.docx by Ye Cao (849948)

“…</p><p>Method: In this study, we applied the mate-pair low pass (∼4X) genome sequencing with large DNA-insert (∼5 kb) in a cohort of 100 patients with neurodevelopmental disorders who did not receive informative results from a routine CNV investigation. …”

Data_Sheet_1_Low-Dose Vitamin D Protects Hyperoxia-Induced Bronchopulmonary Dysplasia by Inhibiting Neutrophil Extracellular Traps.xlsx by Cuie Chen (2372758)

“…</p><p>Methods: Newborn rats were exposed to 90% oxygen continuously for 7 days to mimic BPD, and rats under hyperoxia were injected with 1,25(OH)2D3 at different doses (0.5 ng/g, 3 ng/g). Alveolarization, pulmonary vascular development, inflammatory cytokines and NETs were assessed.…”