TRα2 shows dominant negative activity on positively and negatively regulated T₃ target genes <i>in vivo</i>. by Hajer Guissouma (586934)

“…</b><i>ME-tk-luc</i> transcription was measured in hypothyroid (PTU) 2 days old mice treated with T₃ (2.5 µg/g b.w.) (PTU+T3) or saline (PTU), 18 h after hypothalamic injection of 1 µg reporter construct and 100 ng expression vector (empty pSG5 (Ct) or pSG5-TRα1 (TRα1) or pSG5-TRα2 (TRα2)). …”

Data_Sheet_1_The Sensitivity of Subsurface Microbes to Ocean Warming Accentuates Future Declines in Particulate Carbon Export.pdf by Emma Louise Cavan (6178583)

“…In line with observations from polar regions and the deep ocean we imposed an elevated temperature sensitivity (E_a = 1.0 eV) to cooler regions; firstly to the Southern Ocean (south of 40°S) and secondly where temperature at 100 m depth <13°C. …”

(a) Time-dependent activation (Tyr701 phosphorylation) of signal transducer and activator of transcription 1 (STAT1) by interferon-γ (IFN-γ) in J774 macrophages by Outi Sareila (66176)

“…</p><p></p> Cells were treated with IFN-γ (5 ng/mL) for different times as indicated. Proteins were extracted with modified RIPA-buffer, and the protein contents were measured. …”

Rspo3 inhibits the zygotic Wnt/β-catenin signaling in zebrafish embryos. by Xiaozhi Rong (576365)

“…(<b>E</b>) Rspo3 inhibited Wnt3a activity. Representative views of embryos. The pictures were taken at the 5-somite stage. …”

Role of voice therapy in adherence to voice rest (King et al., 2021) by Renee E. King (11409101)

“…</div><div><b>Results:</b> Talking decreased postprocedure by 63% in the therapy group and 65% in the counseling group, both significantly more than the 35% decrease measured in the evaluation group. …”

Supplementary Material for: Deranged Iron Status Evidenced by Iron Deficiency Characterizes Patients with Hidradenitis Suppurativa by Ponikowska M. (8280024)

“…<b><i>Results:</i></b> Compared with controls, patients with HS demonstrated a deranged iron status as evidenced by decreased levels of ferritin (91 ± 87 vs. 157 ± 99 µg/L), Tsat (21.5 ± 10.8 vs. 42.2 ± 11.7%) and hepcidin (31.3 ± 25.9 vs. 44.2 ± 22.0 ng/mL) (all <i>p</i> < 0.05 vs. controls). …”

Therapeutic Non-Toxic Doses of TNF Induce Significant Regression in TNFR2-p75 Knockdown Lewis Lung Carcinoma Tumor Implants by Sharath P. Sasi (541865)

“…Compared to 3 control groups, p75KD/LLC+TNF showed >2-5-fold decreases in tV (p<0.001) and tW (p<0.0001). …”

IL6/STAT3 modulates estrogen-induced GREB1 transcriptional activity in breast cancer cells. by Mingli Liu (304361)

“…To determine the best efficient concentration for IL-6, hormone-starved MCF-7 cells were treated with various concentrations of IL-6 (0∼100 ng/ml) for 24 h. <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0046410#pone-0046410-g005" target="_blank">Figure 5E</a> shows that the maximum reduction of E2-mediated GREB1 activity is seen at 10 ng/ml, the inhibitory effects are decreased regardless of whether the doses are further increased or decreased throughout the experiment. …”

Mechanisms involved in the regulation of CD36 expression by tumor necrosis factor (TNF)α by Jean Frédéric Boyer (32017)

“…Human monocytes were incubated with macrophage-serum-free medium (M-SFM) alone (control), or with M-SFM containing TNFα (10 ng/ml) for 5, 30 or 60 minutes, and then stimulated, or not, with a synthetic ligand of PPARγ, rosiglitazone (R; 5 μmol/l) for 45 minutes. …”

Bcl11b protein level is down-regulated in the presence of HDAC inhibitors. by Samira Chandwani (474607)

“…N = 3–5; +/− SEM (*p<0.05, **p<0.01, ***p<0.001).</p>…”

Influence of DMF and MMF on NO production of LPS stimulated microglia. by Darius Moharregh-Khiabani (212285)

“…<p>After stimulation for 24 h with 10 ng/ml LPS a dose dependent decrease of NO production in cells incubated with DMF (5, 10, 50µM/ml) could be observed. …”

Antigen-specific response is defective in lupus-prone mice. by Linda A. Lieberman (152611)

“…<p>Splenocytes were collected from infected mice 7 dpi and were stimulated 3 days in vitro with either IL-12 (5ng/ml), STAg (20 ug/ml), or IL-12+ STAg. Supernatants were assayed by ELISA for IFN-gamma production. …”

Search results of kinetic parameter space and prediction of MdmX effect. by Sohyoung Kim (253617)

“…</p>c<p>The presence of MdmX (upto 100 fold k15) decreased maximum value (peak of oscillations) by >30%.…”

Image_2_Influence of Step Frequency on the Dynamic Characteristics of Ventilation and Gas Exchange During Sinusoidal Walking in humans.TIF by Mako Fujita (12403201)

“…<p>We tested the hypothesis that restricting either step frequency (SF) or stride length (SL) causes a decrease in ventilatory response with limited breath frequency during sinusoidal walking. …”

Image_3_Influence of Step Frequency on the Dynamic Characteristics of Ventilation and Gas Exchange During Sinusoidal Walking in humans.TIF by Mako Fujita (12403201)

“…<p>We tested the hypothesis that restricting either step frequency (SF) or stride length (SL) causes a decrease in ventilatory response with limited breath frequency during sinusoidal walking. …”

Do changes in size class composition influence American alligator spatial distributions? by Abby Lawson (750688)

“…The decrease in juvenile size classes we detected may reflect reduced reproductive activity mediated by removal of adults through harvest programs. …”

Image_1_Influence of Step Frequency on the Dynamic Characteristics of Ventilation and Gas Exchange During Sinusoidal Walking in humans.TIF by Mako Fujita (12403201)

“…<p>We tested the hypothesis that restricting either step frequency (SF) or stride length (SL) causes a decrease in ventilatory response with limited breath frequency during sinusoidal walking. …”

Image_4_Influence of Step Frequency on the Dynamic Characteristics of Ventilation and Gas Exchange During Sinusoidal Walking in humans.TIF by Mako Fujita (12403201)

“…<p>We tested the hypothesis that restricting either step frequency (SF) or stride length (SL) causes a decrease in ventilatory response with limited breath frequency during sinusoidal walking. …”

Supermarket policies on less-healthy food at checkouts: Natural experimental evaluation using interrupted time series analyses of purchases by Katrine T. Ejlerskov (6095291)

“…This decrease was sustained at 1 year with 185,100 (121,700–248,500) fewer packages purchased per 4 weeks per percentage market share—equivalent to a 15.5% reduction. …”

Growth states before drug exposure affect survival. by Akihisa Seita (10063260)

“…<p>(A) Decrease of division rate upon drug exposure. …”