Downregulation of Blood-Brain Barrier Phenotype by Proinflammatory Cytokines Involves NADPH Oxidase-Dependent ROS Generation: Consequences for Interendothelial Adherens and Tight J... by Keith D. Rochfort (592433)

“…</p><p>Results</p><p>In response to treatment with either TNF-α or IL-6 (0–100 ng/ml, 0–24 hrs), our studies consistently demonstrated significant dose- and time-dependent decreases in the expression of all interendothelial junction proteins examined, in parallel with dose- and time-dependent increases in ROS generation and HBMvEC permeability. …”

Tyramine exerts hypolipidemic and anti-obesity effects in vivo by Thamires Maria Fontenele Morais (14343099)

“…Tyramine increased adiponectin at 5 mg/L (1.02 ± 0.02 vs. 0.83 ± 0.02 ng/mL) and 10mg/L (0.96 ± 0.04 ng/mL). …”

Modulation of human monocytes by exposure to mitochondrial DNA. by Irene Fernández-Ruiz (5653951)

“…<p>(<b>A</b>) Workflow diagram: MΦs from HV were pre-exposed to mitochondrial DNA isolated from HeLa (mtDNA, 5 µg/ml, white bars), LPS (10 ng/ml, gray bars) or left untreated (black bars) for 5 days, then stimulated for 24 h with LPS, as described in the scheme. …”

Fig 5 - by Alexander M. Dreyer (11785896)

“…Colored sensors denote significant changes (blue = decrease, red = increase) lasting for at least 100 ms in the 2 s windows of interest. …”

Inhaled fluticasone propionate impairs GATA-3 nuclear localization in PBMCs. by Kittipong Maneechotesuwan (372725)

“…(C) Immunoblotting analyses of PBMCs demonstrated a time-dependent decrease in nuclear expression of GATA-3, and increased cytoplasmic GATA-3 expression after inhalation of FP. …”

Stem peptides interact with the dengue virus membrane. by Aaron G. Schmidt (173976)

“…<p>Decrease in pyrene-excimer fluorescence intensity, as a function of the concentration of stem peptide added to pyrene-labeled virions, normalized to its complete loss upon addition of TX100.…”

Effectiveness of a Closed-System Transfer Device in Reducing Surface Contamination in a New Antineoplastic Drug-Compounding Unit: A Prospective, Controlled, Parallel Study by Nicolas Simon (1835062)

“…Gemcitabine amounts were 220.6 and 283.6 ng for the Standard and Phaseal isolators (NS), and ganciclovir amounts were 179.9 and 2.4 ng (p<0.0001).…”

DataSheet1_Dynamics of Dietary Mercury Determined by Mercury Speciation and Isotopic Composition in Dicentrarchus labrax.docx by Marianna Pinzone (8113781)

“…Each group was fed with pellets containing environmentally relevant MeHg concentrations (Control, 200 and 500 ng g⁻¹ dw). We monitored the evolution of MeHg and iHg concentrations as well as Hg isotopic values in liver and muscle. …”

A Single Arm Pilot Study of Effects of Berberine on the Menstrual Pattern, Ovulation Rate, Hormonal and Metabolic Profiles in Anovulatory Chinese Women with Polycystic Ovary Syndro... by Lin Li (28817)

“…The ovulation rate was 25.0% over four months in the whole group, 22.5% in the normal weight group and 31.0% in the overweight/obese group. …”

DataSheet_2_Nitrification and denitrification processes in a zero-water exchange aquaculture system: characteristics of the microbial community and potential rates.pdf by Shuhui Niu (15351196)

“…<p>​The zero-water exchange aquaculture has been identified as a promising method of farming to decrease the environment pressure of aquaculture and to increase profits. …”

DataSheet_1_Nitrification and denitrification processes in a zero-water exchange aquaculture system: characteristics of the microbial community and potential rates.docx by Shuhui Niu (15351196)

“…<p>​The zero-water exchange aquaculture has been identified as a promising method of farming to decrease the environment pressure of aquaculture and to increase profits. …”

DataSheet_1_Vitamin D Supplementation Improves Handgrip Strength in Postmenopausal Women: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.doc by Jia-Li Zhang (112180)

“…Introduction<p>In postmenopausal women, vitamin D deficiency (as defined by the circulating level of 25(OH)D being below 20 ng/ml (50 nmol/L)) is a regular occurrence. The effect of vitamin D supplementation on the muscle function of postmenopausal women has been controversial. …”

Image1_Total flavonoids extracted from Penthorum chinense Pursh mitigates CCl4-induced hepatic fibrosis in rats via inactivation of TLR4-MyD88-mediated NF-κB pathways and regulatio... by Sujuan Wang (1865149)

“…Subsequently, rats were randomly assigned to a control group (Control), a carbon tetrachloride (CCl₄)-induced hepatic fibrosis model group (Model), a positive control group [0.2 mg/(kg∙day)] of Colchicine), and three TFPCP treatment groups [50, 100, and 150 mg/(kg∙day)]. …”

Image2_Total flavonoids extracted from Penthorum chinense Pursh mitigates CCl4-induced hepatic fibrosis in rats via inactivation of TLR4-MyD88-mediated NF-κB pathways and regulatio... by Sujuan Wang (1865149)

“…Subsequently, rats were randomly assigned to a control group (Control), a carbon tetrachloride (CCl₄)-induced hepatic fibrosis model group (Model), a positive control group [0.2 mg/(kg∙day)] of Colchicine), and three TFPCP treatment groups [50, 100, and 150 mg/(kg∙day)]. …”

Lack of tau prevents impaired adult hippocampal progenitor cell proliferation in AICD-Tg mice. by Kaushik Ghosal (244754)

“…Compared to wild-type (left) there is a significant decrease in the number of DCX+ cells in the SGZ of AICD-Tg mice (right). …”

Figure S1 - The Mu Opioid Receptor Promotes Opioid and Growth Factor-Induced Proliferation, Migration and Epithelial Mesenchymal Transition (EMT) in Human Lung Cancer by Frances E. Lennon (541593)

“…<p><b>The MOR antagonist, naltrexone, inhibits epithelial mesenchymal transition (EMT) in human lung cancer cells.</b> <b>Panel A</b>: H358 human NSCLC cells were either untreated, treated with 100 nM morphine, DAMGO, fentanyl or 100 ng/ml EGF for 96 hours with or without pretreatment of cells with the MOR antagonist, naltrexone (100 nM). …”

Decline in SHP2 leads to increases in phospho-p38 to total p38 ratio, nuclear MITF, GPNMB promoter activity, and GPNMB in HepG2 cells. by Sumit Bhattacharyya (14205)

“…Increase was greatest following CASHP2, increasing to 30.9 ± 1.7 ng/mg protein from control level of 5.13 ± 0.13 ng/mg protein. …”

Down-regulation of caveolin-1 expression enhanced Rac1 activity, which was abolished by NSC-23766. by Min Shao (137894)

“…<p>A.Primary PMVECs transfected with control or caveolin-1 shRNA were challenged with TNF-α(100 ng/ml) for 2 hours. …”

SIRT (1–7) mRNA reductions with increasing passage number is augmented with HG treatment in HUVECs. by Rokhsana Mortuza (102995)

“…[*p<0.05 compared to NGP11]. (NG = 5 mM; HG = 25 mM glucose, P = passage number).…”

Effect of apigenin intake on NF-κB activation in the dorsolateral prostate of TRAMP mice. by Sanjeev Shukla (106046)

“…A significant decrease in NF-κB/p65 and NF-κB/p50 is observed after apigenin intake. …”