Simulation results of MR-PL. by Anyi Yang (16643634)

“…The error bar represents twice variance in type I error rate over 100 replications. Notably, the error bar tends to degenerate to a point for those settings with too small variance. …”

SREBP-1 is dispensable but not required for neuritogenic effect of SIM. by Varshiesh Raina (457377)

“…FAS transcripts showed a small decrease at 12 hrs whereas ACC2 transcript showed a significant (<i>p</i> < 0.05^*) decrease at 2 hrs and 12 hrs. …”

Complementary changes in CS duration and firing rate. by Akshay Markanday (11442518)

“…Solid horizontal lines in A and B represent the mean values during the baseline period (−200 to −100 ms from saccade onset), and horizontal dashed lines represent the threshold (3×SD around the mean). …”

Changes to chromatin state with PRMT5 inhibition. by Shelby L. Sloan (10803222)

“…(D) Immunoblot analysis indicates a time dependent decrease in MYC protein after treatment with C220 in 17–71 (100 nM) and CLBL-1 (20 nM). …”

FigureS4 from Early Evaluation of Circulating Tumor DNA as Marker of Therapeutic Efficacy in Metastatic Colorectal Cancer Patients (PLACOL Study) by Fanny Garlan (3153183)

(NZ)CH...O Contacts assist crystallization of a ParB-like nuclease-3 by Neil Shaw (33464)

Kinetic Characterization of the <i>in vitro</i> GST-E6/E6AP-BAP Binding Assay. by Jonathan J. Cherry (501180)

Nuclear import of Avian Sarcoma Virus integrase is facilitated by host cell factors-2 by Mark D Andrake (95479)

“…Quantitative analysis of nuclear import of various GST fusion proteins with (+ comp) and without (no comp) competitor. More than 100 cells were counted for each experimental condition and the percentage of cells that had a mostly nuclear staining for the fusion protein was calculated. …”

supplementary figure: Osimertinib inhibits the MYLK4-mediated phosphorylation of CDKAL1 to suppress stemness and chemoresistance in rhabdomyosarcoma by Takuto Itano (16830105)

“…<p dir="ltr">Supplementary Figure: Identification of osimertinib as an inhibitor of the MYLK4–CDKAL1–SALL2 axis a (left): RT‒qPCR and immunoblotting of RD cells treated with 40 ng/mL epidermal growth factor (EGF) and 2.5 µM osimertinib for 24 h revealed that osimertinib inhibits SALL2 expression in a translation-dependent manner. …”

Quantitative determination of loss of MMP in SH-SY5Y cells in response to Grx1 knockdown. by Uzma Saeed (49670)

“…Cells were treated with vehicle after transfecting them with empty vector, or with vehicle, α-lipoic acid (100 µM) or cyclosporine A (10 µM), 6 hr post transfection with shRNA to Grx1 and MMP was measured using TMRM as the indicator dye. …”

Sequence gaps exclusive to both Archaea and Microsporidia 16S rRNAs. by Chaitanya Muralidhara (223748)

“…(<i>a</i>) The 100 gaps conserved in both the Archaea and Microsporidia map to the entire substructures I–III in the secondary structure model of the bacterium <i>E. coli</i> <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0018768#pone.0018768-Cannone1" target="_blank">[14]</a>. …”

PDBu (1 µM) increases the amplitude of outward K⁺ currents. by Sébastien Hayoz (5656207)

“…<p>Panel A: K⁺ currents elicited by linear voltage ramps varying from −100 to 100 mV. …”

Combined treatments of GTPs and SFN sensitize ERα-negative breast cancer cells for tamoxifen therapy. by Syed M. Meeran (321543)

“…For a comparison, DNMTs inhibitor, AZC (2.5 µM), and HDAC inhibitor, TSA (100 ng), also administrated to MDA-MB-231 cells. …”

Intracellular GSH and GSH/GSSG ratio in monolayer cultures upon induced oxidative stress. by Mireille M. J. P. E. Sthijns (12245491)

“…<p>A) Exposing the monolayer cultures of 0:100, 50:50 and 100:0 INS1E:alphaTC1 cells to 500 μM H₂O₂ only induced a significant decrease in intracellular GSH compared to a monolayer culture not exposed to H₂O₂ in the ratios of 50:50 and 0:100 INS1E:alphaTC1. …”

Acute reduction of Ezh2 induces apoptosis in NSCs. by Falak Sher (151989)

“…Immunostaining of dissociated neurospheres in proliferation medium shows a decrease in proliferation and increase in cell death after using Ezh2-shRNA compared to the control (nc-shRNA). …”

SETD2 mediates the binding of MALAT1 and pSmads. by Jinqiang Zhang (709289)

“…<b>B,</b> RNA immunoprecipitation of MALAT1 by using anti-Smad2/3 or anti-SETD2 antibodies in Hep3B cells (with siSETD2 or siControl transfection) treated with 5ng/mL TGF-β1 or vehicle for 2 hours. The precipitated MALAT1 was assessed by qRT-PCR. …”

Confirmation of Functionality of Constructs and Model System Used by Maarten F Bijlsma (380371)

“…</p> <p>(C) Shh concentration in medium is below the detection limit (5 ng/ml) of Western blotting. Medium was spiked with decreasing concentrations of recombinant Shh, and blotted along with a 4× concentrated medium sample obtained from C3H/10T1/2 fibroblasts (incubated for 16 h at a volume-to-surface ratio identical to the mix-and-match and medium transfer experiments).…”

(A) Schematic presentation of the human AID protein sequence along with the positions of the lysine residues mutated in the various constructs by Said Aoufouchi (49316)

“…(D) Stable BL2 clones expressing the indicated AID-EGFP lysine mutants, WT-AID-EGFP, or mutNLS-AID-EGFP were incubated with cycloheximide (CHX, 50 μg/ml) and LMB (10 ng/ml). The decay of the protein was followed by the decrease in fluorescence intensity. …”

Concentration dependent reduction of IL-6 and CXCL8 by BET inhibitors. by Younis M. Khan (554747)

“…These parameters were used to assess cell viability following treatment with JQ1 (0.5 µM) and PFI-1 (1 µM) for 16 hours. DMSO/Control (<1%) alone, PFI-1, JQ1(-) or JQ1 resulted in only 5% decrease of overall cell viability. …”

Long-term trends of potential years of life lost due to main causes of death in the Slovak population, 2004-2013 by Martin Samohyl (10388448)

“…The PYLL rate is age-standardized and expressed as a sum of all deaths per 100,000. In the period 2004-2013, the highest mean PYLL rates were observed in neoplasms in the whole population (2,103 per 100,000), as well as in females (2,088 per 100,000), with a permanent high significant increase of AAPC of PYLL in both genders. …”