Synthesis and Antiproliferative Activity of a New Series of Mono- and Bis(dimethylpyrazolyl)‑<i>s</i>‑triazine Derivatives Targeting EGFR/PI3K/AKT/mTOR Signaling Cascades by Ihab Shawish (13015516)

Subjects:

N protein of SVCV decreases K48-linked ubiquitination of p53. by Shun Li (330132)

“…<b>(D)</b> N protein decreases the ubiquitination of p53. EPC cells were seeded in 10 cm² dishes and transfected with 5 μg p53-Myc, 5 μg N-Flag or empty vector, and 1 μg HA-Ub. …”

Mefunidone decreased collagen I, collagen III, α-smooth muscle actin (α-SMA) and fibronectin (FN) expression in the obstructive kidneys after UUO at 14 days. by Chunyan Liu (44864)

“…<p><b><i>A</i>.</b> Mefunidone affected collagen I (left) and collagen III (right) protein expression in the obstructed kidneys stained by immunohistochemistry (×200). …”

CGRP decreases LPS-induced IL-1β mRNA levels. by Aichurek Soultanova (3219459)

SRTCX1003 decreases LPS-stimulated cytokine production <i>in vivo</i>. by Hongying Yang (131218)

Cellular stress decreases TDP-43 levels in patient neurons with the TDP-43 A90V mutation. by Zhijun Zhang (315079)

Subjects:

ATG 5 down-regulation decreases human A53T ASYN-induced death in rat cortical neurons. by Maria Xilouri (264240)

miR-181b overexpression decreases cell mitochondrial membrane potential. by Samira Ghorbani (3843895)

EphA4 immunostaining is decreased adjacent to injury site in ephrin-A5-Fc treated mice. by Yona Goldshmit (205708)

“…<p>Immunohistochemical analysis of (A,B) GFAP, (C–F) EphA4 and (G,H) CSPG expression at 2 weeks after spinal cord hemisection and 2 weeks of ephrin-A5-Fc treatment indicated that there was robust GFAP staining in both treated and control mice (A,B). …”

MTT (A) and tryphan blue (B) assay for cell viability. by Tae Ik Chang (283829)

“…<p>HPMCs were incubated for 72 hr with 5.6 mM glucose (NG), NG+ mannitol (94.4 mM, NG+M), high glucose (100 mM, HG), or HG+0.1 µM, 1 µM, or 10 µM simvastatin (HG + statin). …”

AZA decreased AQP1protein content by promoting AQP1 degradation. by Jianzhao Zhang (133200)

Decreased muscle strength is associated with proinflammatory cytokines but not testosterone levels in men with diabetes by J.P. Ferreira (5550653)

Buprenorphine decreased plasma BDNF and serotonin content and altered signaling molecule expression. by Chih-Jen Hung (499000)

Expression of MHC I is decreased by P2X7R activation. by Alberto Baroja-Mazo (441935)

Cysteamine decreased metastasis and prolonged survival in an orthotopic pancreatic cancer mouse model. by Toshio Fujisawa (169513)

BCG-AS−Ndk has decreased intracellular survival due to increased phagolysosome fusion. by Jim Sun (367834)

DLS mGluR1/5 signaling activation in instrumental conditioning and differential behavioral sensitivity to A–O changes with training duration. by Vincent Paget-Blanc (21807763)

Human RBS cells showed severely slow proliferation and decreased protein translation. by Baoshan Xu (158726)

Inhibition of PARP-1 decreased the poly(ADP-ribosyl)ation of Sp1. by Liu Yang (23752)

Estrogen treatment decreases disease severity and the expression of pro-inflammatory cytokines and chemokines. by Lydia C. Cook (548045)