<b>Global pattern and drivers of disease heterogeneity in aging populations</b> by Chengcheng Jin (20326186)

Incidence of ancient variants associated with oncological diseases in modern populations by Draga Toncheva (264197)

GIP Receptor Agonism Attenuates GLP-1 Receptor Agonist Induced Nausea and Emesis in Preclinical Models by Tito Borner (9993148)

TolB is crucial for <i>P. aeruginosa</i> resistance and persistence. by Alessandra Lo Sciuto (610616)

“…(B) Lytic effect of SDS (0–5%), measured as decrease in cell suspension turbidity (OD₆₀₀), on PAO1 wild-type cells (WT, filled circles), TolB-deficient mutant cells (<i>tolB</i>, open diamonds) and TolB-proficient mutant cells (<i>tolB</i> TolB⁺, filled diamonds). …”

Expression of Sox2, Sox10, Gata3, Prox1 and Peripherin during primary auditory neuron development and maturation. by Koji Nishimura (2077804)

“…At E10.5, Sox10 was downregulated as neuroblasts delaminated from the otocyst. …”

Evaluation of emerging NASH therapies: the impact of treatment efficacy profiles on long-term health outcomes: Supplementary materials by William L Herring (14039541)

“…The fibrosis worsening profile reduced predicted 10-year LRC rates (F1:</p> <p>1.9%; F2: 6.5%; F3: 19.1%; F4/CC: 55.0%) more than the resolution and fibrosis improvement profiles</p> <p>(F1: 2.6%/2.6%; F2: 8.5%/8.3%; F3: 23.3%/23.0%; F4/CC: NA/59.0%). …”

Secondary metabolites from <i>Gentiana cruciata</i> L. and their anti-inflammatory and analgesic activities by Rima Konya (14075753)

“…<p>A previously unreported secoiridoid glycoside, cruciatoside (<b>1</b>) was isolated from the aerial parts of <i>Gentiana cruciata</i> L. along with ten known compounds eustomoside (<b>2</b>), eustomorusside (<b>3</b>), gentiopicroside (<b>4</b>), 6'-<i>O</i>-β-D-glucopyranosyl gentiopicroside (<b>5</b>), loganic acid (<b>6</b>), isoorientin (<b>7</b>), isovitexin (<b>8</b>), isovitexin 2''<i>-(E)-</i>ferulate (<b>9</b>), mangiferin (<b>10</b>), and 2-methyl-inositol (<b>11</b>). …”

MPs^PPARα+/+-induced EPC differentiation and <i>in vitro</i> angiogenesis of mature ECs involve NF-κB pathway activation. by Tarek Benameur (196206)

“…<p>(<b>A</b>) Western blot showing that MPs^PPARα+/+ induced I-κB phosphorylation on activator sites (Ser32/36) in EPCs, indicating that NF-κB pathway is activated. …”

Evolutionary dynamics of iPD-population consisting of two types of players: With WSLS and AllD strategies. by Anton M. Unakafov (5706560)

“…<p>(A) Initially, both types have the same frequency, but after 40 generations the fraction of WSLS-players <i>x</i>₁(<i>t</i>) converges to 0 for probabilities to see partner’s choice <i>p</i>_see = 0.0, 0.2 and to 1 for <i>p</i>_see = 0.4, 0.5. …”

Altered TRPV1 staining is observed in DRG obtained from STZ-induced diabetic mice by Reddy M Pabbidi (44094)

“…Summary graph showing increase in mean gray values of TRPV1 staining (n = 5 sections from 4 mice, p < 0.058) in hyperalgesic DRG and decrease in TRPV1 gray value in hypoalgesic diabetic mice (n = 6 sections from 4 mice, p < 0.05) as compared to control non-diabetic mice. . …”

Chemical composition and antioxidant capacity of coffee pulp by Graciela Munguía Ameca (5671427)

“…Ensiling and sun drying did not decrease (P>0.05) caffeine or tannins. No differences were found in caffeic acid (2.031±2.873, 5.103±0.391, 4.913±0.018 mg g-1 DM in FCP, ECP, EDCP, respectively). …”

Effect of Vitrification on the MicroRNA Transcriptome in Mouse Blastocysts by Xueming Zhao (400630)

“…Of these, the expression levels of five miRNAs differed significantly: in the vitrified blastocysts, four miRNAs (mmu-miR-199a-5p, mmu-miR-329-3p, mmu-miR-136-5p and mmu-miR-16-1-3p) were upregulated, and one (mmu-miR-212-3p) was downregulated. …”

FDG PET parameters and survival curves. by Julien Ganem (7490378)

“…<p>Survival curves using the Kaplan-Meier method. <b>(a)</b> PFS was longer for patients with low TLG₂ (HR = 2.8, 95%CI 1.3–5.9, p< 0.01). …”

Germination of fungal pathogen spores in calcium, copper, manganese and zinc chelated with aminoacids by Eloisa Lorenzetti (5021009)

“…For the second assay, the same pathogens had a mean reduction of 52%, 59%, 77%, 87%, 81% and 64% for P. sorghi and 40%, 33%, 17%, 18%, 4% and 2% for Cercospora sp., both at zero, 1, 2, 3, 4 and 5 hours after treatment, respectively. …”

Loss of FHL2 reduces intestinal polyp multiplicity. by Charlotte Labalette (365229)

“…<p>(A) Representative images of intestines from 11-month-old <i>Apc^Δ14/+FHL2^+/+</i> and <i>Apc^Δ14/+FHL2^−/−</i> mouse. …”

SF-E inhibits NMDA-induced ROS production without altering cell viability of primary cortical neurons. by Jinghua Jiang (527159)

“…<p>(A) Exposure of SF-E (0–7.5 µg/mL) to primary cortical neurons for 24 h did not alter neuronal viability as assayed by MTT. …”

Advanced assessment of ductile fracture in steel by X-ray computed tomography by Fabien Léonard (463224)

The proposed mechanism whereby PPi protects against early electrical failure in the course of LDVF. by Junko Shibayama (387144)

Methylation profiling in control and Tet tcKO retinas. Related to Fig 6. by Ismael Hernández-Núñez (10128242)

“…<p><b>(A)</b> Graphic displaying results of WGBS and bACE-seq to distinguish 5mC and 5hmC marks. …”

Experimental strategy and global gene expression dynamics. by Romuald Parmentier (4280983)

“…Note the rapid increase in the number of genes expressed per cell between 5 h and 24 h and the slow decrease after a plateau between 24 h and 72 h. …”