Effect of ACE inhibitors on the binding of a set of anti-ACE mAbs to blood ACE. by Maxim N. Petrov (118931)

“…<p>The binding of a set of 17 mAbs to the N and C domains of human sACE to the human serum ACE was determined using plate precipitation assay <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0049290#pone.0049290-Danilov4" target="_blank">[32]</a>, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0049290#pone.0049290-Danilov9" target="_blank">[49]</a> with ZPHL as a substrate. …”

In-Car Nocturnal Blue Light Exposure Improves Motorway Driving: A Randomized Controlled Trial by Jacques Taillard (125714)

“…<div><p>Prolonged wakefulness greatly decreases nocturnal driving performance. The development of in-car countermeasures is a future challenge to prevent sleep-related accidents. …”

Water interaction and bond strength to dentin of dye-labelled adhesive as a function of the addition of rhodamine B by Linda WANG (5765354)

“…No significance in µTBS between MP and MP-RB for seven days or one year was observed, whereas for SE a decrease in the µTBS means occurred in both storage times. …”

Conflicting selection pressures prevent the outgrowth of TIP-resistant HIV mutants in a host population. by Luke I. Rast (2735782)

Removal of nitrate in raw water using a vertical roughing filter with an external carbon source by Lekhooa Mohobane (14082033)

“…The data shows the residual carbon measured in the filtrate when employing a filter with a carbon source at carbon to nitrogen (C/N) ratio of 1.05, 1.08 and 1.1 and inflow nitrate concentration of 15 mg/L-N, 25 mg/L-N and 50 mg/L-N respectively.…”

Optimized TMS recapitulates DNA methylation levels measured with the EPIC array and WGBS. by Amy Longtin (21409957)

Inflammation and Gli2 Suppress Gastrin Gene Expression in a Murine Model of Antral Hyperplasia by Milena Saqui-Salces (126581)

“…Using a mouse model of constitutively active epithelial GLI2 expression, we found that activated GLI2 repressed <em>Gast</em> expression but induced <em>Il-1β</em> gene expression and proliferation in the gastric antrum, along with a reduction of the number of G-cells. …”

Failure of Passive Immune Transfer in Calves: A Meta-Analysis on the Consequences and Assessment of the Economic Impact by Didier Raboisson (2833616)

“…FPT is associated with an increased risk of mortality and decreased health and longevity. Despite the known management practices associated with low FPT, it remains an important issue in the field. …”

Number of captured on-target sites and average site-based coverage for each plexing strategy. by Amy Longtin (21409957)

Endocrine Determinants of Changes in Insulin Sensitivity and Insulin Secretion during a Weight Cycle in Healthy Men by Judith Karschin (696523)

“…Weight regain-induced decrease in postprandial IS correlated with increases in adiponectin, fT3, TSH, GL of the diet and a decrease in ghrelin levels (r-values between -0.40 and 0.83, p<0.05) whereas increases in early and total insulin secretion were associated with a decrease in leptin/adiponectin-ratio (r = -0.52 and r = -0.46, p<0.05) and a decrease in fT4 (r = -0.38, p<0.05 for total insulin secretion only). …”

Phenology and Seed Yield Performance of Determinate Soybean Cultivars Grown at Elevated Temperatures in a Temperate Region by Doug-Hwan Choi (3330894)

“…Heat stress conditions induced a decrease in pod number to a greater degree than in seed number per pod. …”

ITR calculation for hypothetical cases of typing a 10 character sequence with error correction in 10 minutes. by William Speier (475066)

Performance of CNN models. by Fang-Rong Hsu (13983021)

Early mobilization of critically ill patients in the intensive care unit: A systematic review and meta-analysis by Lan Zhang (90951)

“…Early mobilization decreased the incidence of ICU-acquired weakness (ICU-AW) at hospital discharge (three studies, 190 patients, relative risk (RR): 0.60, 95% confidence interval (CI) [0.40, 0.90]; <i>p</i> = 0.013, <i>I</i>^<i>2</i> = 0.0%), increased the number of patients who were able to stand (one study, 50 patients, 90% vs. 62%, <i>p</i> = 0.02), increased the number of ventilator-free days (six studies, 745 patients, standardized mean difference (SMD): 0.17, 95% CI [0.02, 0.31]; <i>p</i> = 0.023, <i>I</i>^<i>2</i> = 35.5%) during hospitalization, increased the distance the patient was able to walk unassisted (one study, 104 patients, 33.4 (0–91.4) meters vs. 0 (0–30.4) meters, <i>p</i> = 0.004) at hospital discharge, and increased the discharged-to-home rate (seven studies, 793 patients, RR: 1.16, 95% CI [1.00, 1.34]; <i>p</i> = 0.046). …”

Image_1_Oat polar lipids and sunflower lecithin similarly improve cardiometabolic risk markers and appetite controlling hormone responses after breakfast and a subsequent lunch. A... by Mohammad Mukul Hossain (20128593)

“…Dietary intake of bioactive compounds found in foods are linked to a decrease likelihood of these disorders. For this purpose, a randomized crossover meal study was performed to compare the postprandial metabolic effects of lecithin and oat polar lipids in healthy subjects.…”

HS induces a rapid degeneration of the nuclei of the MB neurons in the absence of dPGAM5. by Yosuke Ishida (185168)

“…The genotypes are <i>c739-GAL4/+; UAS-mCD8::GFP/+</i> (Control) and <i>PGAM5¹</i>/<i>Y; c739</i>-<i>Gal4</i>/+; <i>UAS</i>-<i>mCD8::GFP</i>/+ (<i>PGAM5¹</i>). Scale bar (<b>A</b>–<b>H</b>) = 50 µm. Representative images of the KC nuclei visualized by Histone2B::ECFP (<b>I</b>–<b>L</b>; scale bar = 20 µm) and the total number of KC nuclei (<b>M</b>) are shown. …”

Bone Morphogenetic Protein for the Healing of Tibial Fracture: A Meta-Analysis of Randomized Controlled Trials by Jiezhi Dai (500546)

“…For acute tibial fracture, BMP group was associated with a higher rate of union (RR, 1.16; 95% CI, 1.04 to 1.30) and a lower rate of revision (RR, 0.68; 95% CI, 0.54 to 0.85) compared with control group. …”

DataSheet_1_Serum C-Reactive Protein and Periodontitis: A Systematic Review and Meta-Analysis.docx by Vanessa Machado (5516684)

“…Intensive NSPT induced an immediate increase of hs-CRP followed by a progressive decrease whilst non-intensive NSPT consistently decreased hs-CRP after treatment up to 180 days (p<0.001). …”

Efficacy of inhibition depends on spatial and temporal features of GABA_AR input. by Nicolas Doyon (344567)

“…Note that this is the optimal frequency for activation of a single “test” synapse; optimal input frequency would necessarily decrease as the number of activated synapses increased, although the exact relationship would depend on the spatial distribution of those active synapses (see <b>A</b>) as well as the level of background synaptic activity.…”

Unique challenges required reassessment and alterations to critical reagents to rescue a neutralizing antibody assay by Blake A Rowe (19589318)

“…</p> <p><b>Results & conclusion:</b> A larger dynamic range, high inhibition and higher drug tolerance were achieved by adding an acid dissociation step to the assay, performing atypical biotin labeling of Drug 1 and switching to a detection target that contained an Fc linker to increase steric hinderance and decrease its binding affinity to Drug 1.…”