DataSheet_1_A cyclic peptide-based PROTAC induces intracellular degradation of palmitoyltransferase and potently decreases PD-L1 expression in human cervical cancer cells.docx by Yu-Ying Shi (15975992)

“…Introduction<p>Our previous research has found that degradation of palmitoyltransferase in tumor cells using a linear peptide PROTAC leads to a significant decrease in PD-L1 expression in tumors. …”

Decreasing rates of disorganised attachment in infants and young children, who are at risk of developing, or who already have disorganised attachment. A systematic review and meta-... by Barry Wright (313307)

Inflammatory conditions decrease CD36 expression and CD36-mediated <i>Pf</i>PEs phagocytosis through downregulation of PPARγ. by David Olagnier (205583)

Effect of the stabilized MetA on the persister cell frequency under acidic conditions. by Elena A. Mordukhova (646403)

Exposure of HOB to chemotherapeutic agents or rTGF-β1 decreased the expression of CXCL-12 and diminished support of pro-B cell chemotaxis. by Stephanie L. Rellick (182765)

Five compounds significantly decrease MAPK1 phosphorylation in K562 cells. by Pamela Y. Ting (713174)

Effect of L-methionine on the frequency of persisters at different temperatures. by Elena A. Mordukhova (646403)

Effect of specific inhibitors on CYP-mediated CK (50 μM) metabolism in HLMs. by Jian Xiao (253329)

IL-6-induction of Nox2 and subsequent decrease of parvalbumin and GAD67 expression in PV-positive interneurons is NFκB-dependent. by Laura L. Dugan (264427)

“…(b) Application of IL-6 to neurons in culture induced Nox2 expression (b, top panel) and DHE oxidation (b, bottom panel and c) that was blocked by the NFκB inhibitor SN50. Dissociated primary neuronal cultures were treated with IL-6 (10 ng/ml) for 24 h in the absence or presence of SN50 (5 µM), an inhibitor of NFκB nuclear translocation. …”

Assays of TUNEL revealed a decreased number of apoptotic cell after oroxylin A treatment. by Shu-Fang Lin (4167091)

<i>T. cruzi</i> PCM abrogates MAP kinase activation and decreased MAP kinase signaling results in inhibition of ctgf/ccn2 expression. by G. Adam Mott (198973)

5-hmC is increased during THP1 macrophage differentiation. by Fangfang Sun (2410654)

Mean and standard deviation values for the Impulse during the first 50 ms of stance (Imp50) during running shod (SH) and barefoot (BF), in both PRE and POST training, where (<sup>a... by Ana Paula da Silva Azevedo (3373688)

Ara-C treatment caused a decrease in microglia, NG2+ progenitors, oligodendrocytes, astrocytes and T cells in the spinal cord of SOD1^G93A mice. by Jean-Nicolas Audet (326107)

PSD-95 decreased ASIC2a acid-evoked current. by Anne Marie S. Harding (546425)

Impact of 8-MOP concentration (0 ng/ml, 200 ng/ml, or 300 ng/ml) on cellular response after a 2 J/cm² UVA dose. by Marie Laulhé (6416483)

Two-Arm Randomized Pilot Intervention Trial to Decrease Sitting Time and Increase Sit-To-Stand Transitions in Working and Non-Working Older Adults by Jacqueline Kerr (785884)

Evaluation of ethanol extract of Punica granatum (Pomegranate) peel decrease in viral replication of BoHV-1 in Colorado murine embryos experimentally infected by Eduardo Gimenes Palazzi (5671100)

“…The murine embryos treated with PgEE showed satisfactory results: no morphological changes, cleavage rate similar to controls, despite the detection of the presence of virus by nested PCR and TEM, there was a decrease of the viral titer after the treatment with this extract, which suggests interference of this treatment in the viral cycle BoHV-1 Colorado without altering the embryo development.…”

Extracellular vesicles isolated from patients undergoing remote ischemic preconditioning decrease hypoxia-evoked apoptosis of cardiomyoblasts after isoflurane but not propofol expo... by Frederik Abel (8452101)

“…Hypoxia increased apoptosis of H9c2 cells (hypoxia: 8.4%±0.6; normoxia: 2.5%±0.1; p<0.0001). RIPC-EVs decreased H9c2 cell apoptosis compared to control (apoptotic ratio: 0.83; p = 0.0429) while Sham-EVs showed no protection (apoptotic ratio: 0.97). …”

The blood plasma, kidney, and brain concentration levels (ng/ml) of GSK360A presented for 5 and 24 hours after GSK360A (30 mg/kg) was administered orally by gavage. by Jin Zhou (90734)