First-in-Class Hydrazide-Based HDAC6 Selective Inhibitor with Potent Oral Anti-Inflammatory Activity by Attenuating NLRP3 Inflammasome Activation by Kairui Yue (11874403)

“…Low-dose <b>35m</b> remarkably decreases LPS-induced IL-1β release both <i>in vitro</i> and <i>in vivo</i> by blocking the activation of NLRP3, indicating that <b>35m</b> can be a potential orally active therapeutic agent for the treatment of NLRP3-related diseases.…”

A decreased yield of RNP1, RNP2 and RNP5 formation in the presence of protein aGAR1 is counteracted by RNA-S by Bruno Charpentier (9519)

Whole sample storing experiment: Mean FECs of day 0, day 1 and day 2 for hookworm, <i>A</i>. <i>lumbricoides</i> and <i>T</i>. <i>trichiura</i>. by Felix Bosch (10024550)

Inhibition of ILK Decreases Bipolar and Multipolar Cytokinesis while Increasing Survival of Multinucleated Cells. by William K. A. Sikkema (574881)

Apoptosis is enhanced in DCE- or CS-treated keratinocytes. by Claudia Scarponi (205759)

Network of genes targeted by miR-6883-5p. by Sherin Bakhashab (3451835)

Regadenoson increases survival of SARS-CoV-2-infected K18-mice. by Joseph Rabin (7399436)

Subjects:

sAxl levels in relation to treatment outcomes. by Ioannis Parodis (2851211)

Total BAL cell numbers and cell differential counts. by Ana Fernandez-Bustamante (766266)

Definitions of social influence metrics (i.e., betweenness centrality or age category) network level indices (weighted (W) diameter, global efficiency and modularity, as well as un... by Maggie Wiśniewska (11965538)

Measurements of HO-1 and dephosphorylated p38-MAPK concentrations in alveolar macrophages. by Ana Fernandez-Bustamante (766266)

Changes of anti-oxidative enzyme and oxidative stress after in a mouse model of kidney fibrosis. by Wencheng Jin (13136262)

Subjects:

Changes related to kidney staining in UUO mouse model. by Wencheng Jin (13136262)

Subjects:

Changes associated with kidney fibrosis and effects of MN705 treatment on TGF- by Wencheng Jin (13136262)

Subjects:

The screening process of MN705. by Wencheng Jin (13136262)

Subjects:

Changes associated with kidney fibrosis in TGF- by Wencheng Jin (13136262)

Subjects:

Effect of MN705 treatment on TGF- by Wencheng Jin (13136262)

Subjects:

Validation of MN705 treatment effects in human proximal tubular epithelial cells during TGF- by Wencheng Jin (13136262)

Subjects:

Lung injury features. by Ana Fernandez-Bustamante (766266)

S2 File - by Yosuke Kameno (342665)

“…This initial increase and subsequent decrease in K6 and FCV-19S were more prominent in individuals with high trait anxiety (K6: B = 1.55, 95% CI = 1.18 to 1.91; FCV-19S: B = 4.27, 95% CI = 2.50 to 6.04) and in occupations other than physicians or nurses. …”