Discovery of Novel Acridane-Based Tubulin Polymerization Inhibitors with Anticancer and Potential Immunomodulatory Effects by Xiaopeng Peng (9136955)

“…Importantly, the combination of <b>NT-6</b> with a small-molecule PD-L1 inhibitor NP-19 decreased tumor burden significantly (TGI% = 77.6%). …”

Discovery of Novel Acridane-Based Tubulin Polymerization Inhibitors with Anticancer and Potential Immunomodulatory Effects by Xiaopeng Peng (9136955)

“…Importantly, the combination of <b>NT-6</b> with a small-molecule PD-L1 inhibitor NP-19 decreased tumor burden significantly (TGI% = 77.6%). …”

Evolutionary transitions of gamete dimorphism and gametogenesis induction cues in volvocine algae. by Hiroko Kawai-Toyooka (382362)

Excel Sheets for Graphs. by Chunxia Wang (766713)

The average accuracy (across all specialties) for the highest performing classifiers (when optimized for <i>F</i>₁Score) by different lengths of the referral notes (as m... by Mohamed Abdalla (10100115)

Distinct characteristics and outcomes in elderly-onset IgA vasculitis (Henoch-Schönlein purpura) with nephritis: Nationwide cohort study of data from the Japan Renal Biopsy Registr... by Hiroyuki Komatsu (2292505)

“…Significantly more elderly than adult patients developed a 50% increase in sCr during a mean observation period of 3.9 years (21.7% vs. 4.7%, p = 0.012), and significantly fewer elderly, than adult patients achieved clinical remission (23.9% vs. 46.2%, p = 0.016). …”

Lead Optimization of Androgen Receptor-HSP27 Disrupting Agents in Glioblastoma by Yaxin Li (312731)

“…Compounds <b>4</b> and <b>6</b> exhibit IC₅₀s of 35 and 23 nM, respectively, to inhibit cell proliferation and also show significant activity to decrease the tumor growth <i>in vivo</i>.…”

Simulated treatments with 4–way, 3–way, 2–way regimen comparison from HRZEM. by Maral Budak (6680351)

DataSheet1_The Variants at APOA1 and APOA4 Contribute to the Susceptibility of Schizophrenia With Inhibiting mRNA Expression in Peripheral Blood Leukocytes.pdf by Yao Fan (1977274)

“…After the SZ patients received an average of 27.50 ± 9.90 days of antipsychotic treatment, the median (interquartile) of serum apoA1 in the SZ episode significantly increased from 1.03 (1.00.1.20) g/L to 1.08 (1.00.1.22) g/L with the p-value of 0.044.…”

DataSheet_1_DNA N6-Methyladenine (6mA) Modification Regulates Drug Resistance in Triple Negative Breast Cancer.pdf by Xianneng Sheng (10076839)

Enhanced Reaction Kinetics in Stationary Two-Phase Flow through Porous Media by Xueyi Zhang (2019148)

The infected silkworm ovarioles on the fifth day of pupation. by Chunxia Wang (766713)

<i>N</i>. <i>bombycis</i> bound with BmVg domains VWD and DUF1943. by Chunxia Wang (766713)

Chemical composition of the surface layer of the original cork and of the cork samples after outdoor exposure and soil burial, regarding extractives soluble in dichloromethane (DCM... by Isabel Miranda (8055)

Characterization of recent and minimally passaged Brazilian dengue viruses inducing robust infection in rhesus macaques by Maria Beatriz Borges (5142965)

Discovery of 2‑Ethoxy-5-isobutyramido‑<i>N</i>‑1-substituted Benzamide Derivatives as Selective Kv2.1 Inhibitors with In Vivo Neuroprotective Effects by Jie Zhou (28945)

“…In this work, a series of novel benzamide derivatives were designed and synthesized as Kv2.1 inhibitors, and extensive structure–activity relationships led to highly potent and selective Kv2.1 inhibitors having IC₅₀ values of 10^–8 M. …”

Discovery of 2‑Ethoxy-5-isobutyramido‑<i>N</i>‑1-substituted Benzamide Derivatives as Selective Kv2.1 Inhibitors with In Vivo Neuroprotective Effects by Jie Zhou (28945)

“…In this work, a series of novel benzamide derivatives were designed and synthesized as Kv2.1 inhibitors, and extensive structure–activity relationships led to highly potent and selective Kv2.1 inhibitors having IC₅₀ values of 10^–8 M. …”

Discovery of 2‑Ethoxy-5-isobutyramido‑<i>N</i>‑1-substituted Benzamide Derivatives as Selective Kv2.1 Inhibitors with In Vivo Neuroprotective Effects by Jie Zhou (28945)

“…In this work, a series of novel benzamide derivatives were designed and synthesized as Kv2.1 inhibitors, and extensive structure–activity relationships led to highly potent and selective Kv2.1 inhibitors having IC₅₀ values of 10^–8 M. …”

S5 File - by Marian Adan (16641634)

S3 File - by Marian Adan (16641634)