Descriptive statistics. by Mireia Jofre-Bonet (728653)

Attributes and levels used in the DCE. by Mireia Jofre-Bonet (728653)

Phosphatidylserine and pridopidine increase IKAP levels in FD cells through the same mechanism. by Sivan Yannai (3594626)

Description of the studied population (N = 710). by Maryo Baakliny (20910279)

“…<div><p>The emergence of the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the subsequent coronavirus disease 2019 (COVID-19) pandemic with the continuous evolution of the virus into variants such as Alpha, Beta, Delta, Omicron and others necessitates an on-going surveillance and evaluation of vaccine effectiveness (VE).This study focuses on assessing the real-world performance of the Pfizer-BioNTech (BNT162b2) vaccine against the Omicron variant. This study employs a test-negative, case-control design, a methodology commonly utilized for estimating the VE in influenza studies. …”

Preventive measures during COVID-19 pandemic. by Maryo Baakliny (20910279)

“…<div><p>The emergence of the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the subsequent coronavirus disease 2019 (COVID-19) pandemic with the continuous evolution of the virus into variants such as Alpha, Beta, Delta, Omicron and others necessitates an on-going surveillance and evaluation of vaccine effectiveness (VE).This study focuses on assessing the real-world performance of the Pfizer-BioNTech (BNT162b2) vaccine against the Omicron variant. This study employs a test-negative, case-control design, a methodology commonly utilized for estimating the VE in influenza studies. …”

Probability of identity (PI) combining 83 autosomal SNPs. by Ida-Maria Blåhed (5318195)

Boron Nitride Nanotubes: Force Field Parameterization, Epoxy Interactions, and Comparison with Carbon Nanotubes for High-Performance Composite Materials by Swapnil S. Bamane (14664978)

Hybrid Molecules of Benzothiazole and Hydroxamic Acid as Dual-Acting Biofilm Inhibitors with Antibacterial Synergistic Effect against Pseudomonas aeruginosa Infections by Zhen-Meng Zhang (20874497)

“…This study synthesized benzothiazole-conjugated hydroxamic acid derivatives as dual-acting biofilm inhibitors, and compound <b>JH21</b> was identified as the hit compound with potent submicromolar biofilm inhibitory activity (IC₅₀ = 0.4 μM). Further mechanistic studies demonstrated not only that the production of virulence was decreased through mainly inhibiting QS system but also that <b>JH21</b> competed for iron with the high-affinity siderophore pyoverdine, inducing iron deficiency and inhibiting biofilm. …”

Development and testing of AAV-delivered single-chain variable fragments for the treatment of methamphetamine abuse by Charles E. Hay (5470526)

“…These results suggest that AAV-delivered scFv could be a promising therapy to treat methamphetamine abuse.…”

The food consumption quantity. by Bingtao Su (4740009)

Selexipag: An Oral and Selective IP Prostacyclin Receptor Agonist for the Treatment of Pulmonary Arterial Hypertension by Tetsuo Asaki (1366140)

Selexipag: An Oral and Selective IP Prostacyclin Receptor Agonist for the Treatment of Pulmonary Arterial Hypertension by Tetsuo Asaki (1366140)

Nampt overexpression attenuated cell senescence in MSCs obtained from the old group. by Cao Ma (3710134)

Determinants for Substrate Recognition in the Glycyl Radical Enzyme Benzylsuccinate Synthase Revealed by Targeted Mutagenesis by Iryna Salii (10219821)

Discovery of Novel Pyrimidine-Based Capsid Assembly Modulators as Potent Anti-HBV Agents by WooChan Kim (10690503)

“…Moreover, treatment with compound <b>23h</b> for 5 weeks significantly decreased serum levels of HBV DNA levels (3.35 log reduction) in a human liver-chimeric uPA/SCID mouse model, and these effects were significantly increased when <b>23h</b> was combined with tenofovir, a nucleotide analogue inhibitor of reverse transcriptase used for the treatment of HBV infection.…”

Isoindolin-1-ones Fused to Barbiturates: From Design and Molecular Docking to Synthesis and Urease Inhibitory Evaluation by Houman Kazemzadeh (12742141)

“…In vitro urease inhibitory results indicated that all the compounds had higher inhibitory activity than the standard inhibitor, thiourea, and compound <b>5b</b> proved to be the most potent inhibitor (IC₅₀ = 0.82 ± 0.03 μM). A molecular docking study was performed to understand the interaction between compounds <b>5a–n</b> and Jack bean urease enzyme. …”

GFP+ NPC Implant Apoptosis. Implants were sectioned and immunostained for the early effector caspase, cleaved caspase-3 (red, GFP = green, DAPI = blue) and area of fluorescence rel... by Cicely Williams (291856)

“…<p>This initially higher rate of apoptosis significantly decreased by day 5 (0.036±0.050, p = 0.0063) to a rate comparable to that of the NPC∶BEC implants. …”

<i>In silico</i> screening identifies doxazosin as a novel agonist for EphA2 receptor. by Aaron Petty (143170)

“…Note decreasing amount of EphA2 following ephrin-A1 and doxazosin treatment. …”

Zwitterion-Functionalized Cuprous Oxide Nanoparticles for Highly Specific and Enzymeless Electrochemical Creatinine Biosensing in Human Serum by R. K. Rakesh Kumar (14241205)

“…A linear response to creatinine concentration from 10 to 200 μM (<i>R</i>² = 0.9876 and LOD = 5.0 μM) was observed, which covers the entire range of physiological creatinine in human serum. …”

CRISPR-Cas9-mediated mutation analysis of T₀ Stmc7 mutants. by Bikram Poudel (15989201)