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ng decrease » _ decrease (Expand Search), a decrease (Expand Search), we decrease (Expand Search)
nn decrease » _ decrease (Expand Search), a decrease (Expand Search), mean decrease (Expand Search)
ng decrease » _ decrease (Expand Search), a decrease (Expand Search), we decrease (Expand Search)
nn decrease » _ decrease (Expand Search), a decrease (Expand Search), mean decrease (Expand Search)
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2601
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2602
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2603
Downregulation of Blood-Brain Barrier Phenotype by Proinflammatory Cytokines Involves NADPH Oxidase-Dependent ROS Generation: Consequences for Interendothelial Adherens and Tight J...
Published 2014“…</p><p>Results</p><p>In response to treatment with either TNF-α or IL-6 (0–100 ng/ml, 0–24 hrs), our studies consistently demonstrated significant dose- and time-dependent decreases in the expression of all interendothelial junction proteins examined, in parallel with dose- and time-dependent increases in ROS generation and HBMvEC permeability. …”
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2604
HMGB1 Attenuates Cardiac Remodelling in the Failing Heart via Enhanced Cardiac Regeneration and miR-206-Mediated Inhibition of TIMP-3
Published 2011“…HMGB1 also enhanced MMP2 and MMP9 activity and decreased TIMP-3 levels. Importantly, miR-206 expression 3 days after HMGB1 treatment was 4-5-fold higher than in control hearts and 20–25 fold higher that in sham operated hearts. …”
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2605
Table_1_Patient-Specific Assays Based on Whole-Genome Sequencing Data to Measure Residual Disease in Children With Acute Lymphoblastic Leukemia: A Proof of Concept Study.docx
Published 2022“…Limit of quantifiability (LoQ) and limit of detection (LoD) for the ddPCR assays (n = 15) were up to 10<sup>−5</sup> and 10<sup>−6</sup>, respectively. All targets were readily detectable in a multiplexed ddPCR with minimal DNA input (1 ng of gDNA) at a 10<sup>−1</sup> dilution, and targets for half of the patients were also detectable at a 10<sup>−2</sup> dilution. …”
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2606
Table_3_Patient-Specific Assays Based on Whole-Genome Sequencing Data to Measure Residual Disease in Children With Acute Lymphoblastic Leukemia: A Proof of Concept Study.xlsx
Published 2023“…Limit of quantifiability (LoQ) and limit of detection (LoD) for the ddPCR assays (n = 15) were up to 10<sup>−5</sup> and 10<sup>−6</sup>, respectively. All targets were readily detectable in a multiplexed ddPCR with minimal DNA input (1 ng of gDNA) at a 10<sup>−1</sup> dilution, and targets for half of the patients were also detectable at a 10<sup>−2</sup> dilution. …”
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2607
Supplementary file 1_Proof-of-concept of a prior validated LC-MS/MS method for detection of N-lactoyl-phenylalanine in dried blood spots before, during and after a performance diag...
Published 2025“…</p>Results<p>Lac-phe concentrations increased from 31.5 ± 10 nmol/L at baseline to a maximum of 101.0 ± 40.1 nmol/L at time-to-exhaustion after the second incremental test. 15 min after exercise, lac-phe concentration decreased to 89.7 ± 30.4 nmol/L. …”
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2608
Table_2_Patient-Specific Assays Based on Whole-Genome Sequencing Data to Measure Residual Disease in Children With Acute Lymphoblastic Leukemia: A Proof of Concept Study.xlsx
Published 2023“…Limit of quantifiability (LoQ) and limit of detection (LoD) for the ddPCR assays (n = 15) were up to 10<sup>−5</sup> and 10<sup>−6</sup>, respectively. All targets were readily detectable in a multiplexed ddPCR with minimal DNA input (1 ng of gDNA) at a 10<sup>−1</sup> dilution, and targets for half of the patients were also detectable at a 10<sup>−2</sup> dilution. …”
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2609
The metoclopramide-induced reestablishment of PRL synthesis in infected mice prevents thymus atrophy.
Published 2013“…Intrathymic levels of corticosterone were increased in MET-treated mice whereas PRL decreased, as demonstrated in <b>G</b>. Uninfected and infected mice received daily MET (2.5 mg/kg/100 µl, s.c.) from 10 to 14 dpi, or PBS as negative control. …”
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2610
Table_2_Patient-Specific Assays Based on Whole-Genome Sequencing Data to Measure Residual Disease in Children With Acute Lymphoblastic Leukemia: A Proof of Concept Study.xlsx
Published 2022“…Limit of quantifiability (LoQ) and limit of detection (LoD) for the ddPCR assays (n = 15) were up to 10<sup>−5</sup> and 10<sup>−6</sup>, respectively. All targets were readily detectable in a multiplexed ddPCR with minimal DNA input (1 ng of gDNA) at a 10<sup>−1</sup> dilution, and targets for half of the patients were also detectable at a 10<sup>−2</sup> dilution. …”
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2611
Table_3_Patient-Specific Assays Based on Whole-Genome Sequencing Data to Measure Residual Disease in Children With Acute Lymphoblastic Leukemia: A Proof of Concept Study.xlsx
Published 2022“…Limit of quantifiability (LoQ) and limit of detection (LoD) for the ddPCR assays (n = 15) were up to 10<sup>−5</sup> and 10<sup>−6</sup>, respectively. All targets were readily detectable in a multiplexed ddPCR with minimal DNA input (1 ng of gDNA) at a 10<sup>−1</sup> dilution, and targets for half of the patients were also detectable at a 10<sup>−2</sup> dilution. …”
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2612
Native protein splicing in <i>Cne</i> is inhibited by copper.
Published 2019“…Lanes are as follows: (+), 2.5 ng of overexpressed pET47b <i>Cne</i> Prp8 intein in <i>E</i>. …”
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2613
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2614
DataSheet_1_Hsp90 Levels in Idiopathic Inflammatory Myopathies and Their Association With Muscle Involvement and Disease Activity: A Cross-Sectional and Longitudinal Study.docx
Published 2022“…</p>Results<p>Hsp90 plasma levels were increased in IIM patients compared to HC (median [IQR]: 20.2 [14.3–40.1] vs 9.8 [7.5–13.8] ng/mL, p<0.0001). Elevated Hsp90 was found in IIM patients with pulmonary, cardiac, esophageal, and skeletal muscle involvement, with higher disease activity or damage, and with elevated muscle enzymes and crucial cytokines/chemokines involved in the pathogenesis of myositis (p<0.05 for all). …”
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2615
OVA cross-presentation is inhibited in most matured DCs.
Published 2013“…<p>(A) Immature DCs were activated for 22h with 1µg/ml CD40L, 1µM CpG, 0.1µg/ml LPS or 20ng/ml TNF-α or left untreated (UT). Then, OVA-coated beads were added for 5h. …”
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2616
DataSheet1_Inflammation-related pathways involved in damaged articular cartilage of rats exposed to T-2 toxin based on RNA-sequencing analysis.xlsx
Published 2022“…Also, Mmp3, Tnf, Mapk10, Ccl11, Creb5, Cxcl2, and Cebpb were significantly enriched in the two pathways. …”
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2617
Expression Rescue of HS1 Mutants in HS1-depleted NK Cells.
Published 2015“…Immunoblots probed with anti-Phospho-Tyr397 and anti-HS1. NK cells (5 x 10<sup>6</sup>) treated with SDF-1α (30 ng/mL) for the indicated times (min). …”
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2618
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2619
Anti-TNF therapy can reverse the age-associated increase in circulating Ly6C<sup>high</sup> monocytes.
Published 2016“…<p>(A-B) Young mice were give 200 ng/ml of TNF intraperitoneally every other day for 3 weeks. …”
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2620
Table_1_Patient-Specific Assays Based on Whole-Genome Sequencing Data to Measure Residual Disease in Children With Acute Lymphoblastic Leukemia: A Proof of Concept Study.docx
Published 2023“…Limit of quantifiability (LoQ) and limit of detection (LoD) for the ddPCR assays (n = 15) were up to 10<sup>−5</sup> and 10<sup>−6</sup>, respectively. All targets were readily detectable in a multiplexed ddPCR with minimal DNA input (1 ng of gDNA) at a 10<sup>−1</sup> dilution, and targets for half of the patients were also detectable at a 10<sup>−2</sup> dilution. …”