Characterization of Cadherin-11 expression in the Tsk-1 mouse model of skin fibrosis. by Mesias Pedroza (212574)

Voxel-wise analysis of DTI and Tinetti mobility. by Nicola Moscufo (601838)

Examples of retinal venular assessment from two subjects with different diet quality. by Ling-Jun Li (729635)

Immunohistochemical staining at the limbus at post-exposure 3 hours. by Chun-Ting Lai (791855)

Effect of MNC hUCB cell administration on microglial cell density in the spinal cord of G93A mice. by Svitlana Garbuzova-Davis (81764)

“…A) In the cervical spinal cord, mice receiving 10×10⁶ MNC hUCB cells showed significantly (p<0.001) higher microglial cell density vs. mice with 25×10⁶ and 50×10⁶ cell doses. …”

Bone metabolism dynamics in the early post-transplant period following kidney and liver transplantation by Peter W. Schreiber (4042775)

“…Six months post-transplant median 1, 25-(OH)₂ vitamin D levels increased by >300% (from 9.1 to 36.5ng/l; <i>P</i><0.001) and median intact parathyroid hormone levels decreased by 68.4% (from 208.7 to 66.0 ng/l; <i>P</i><0.001). …”

Phenotypic deficits in the HIV-1 envelope are associated with the maturation of a V2-directed broadly neutralizing antibody lineage - Fig 3 by Lucia Reh (546554)

The Reversal Effects of 3-Bromopyruvate on Multidrug Resistance <i>In Vitro</i> and <i>In Vivo</i> Derived from Human Breast MCF-7/ADR Cells by Long Wu (655081)

“…Multidrug resistance reversal by 3-Bromopyruvate occurred through at least three approaches, namely, a decrease in the intracellular level of ATP and HK-II bioactivity, the inhibition of ATPase activity, and the slight decrease in P-glycoprotein expression in MCF-7/ADR cells.…”

Protein and mRNA noise are inversely correlated with abundance. by Roy D. Dar (816541)

PowerPoint Slides for: Urinary Periostin Excretion Predicts Renal Outcome in IgA Nephropathy by Hwang J.H. (3300987)

“…Histologically, group 3 patients were correlated with severe interstitial fibrosis/tubular atrophy (p = 0.004), interstitial inflammation (p = 0.007), hyaline arteriolosclerosis (p = 0.001) and glomerular sclerosis (p < 0.001). A higher initial uPOSTN/Cr level was associated with a greater decline in eGFR during follow-up (p = 0.043 when initial eGFR ≥60; p = 0.025 when eGFR <60 ml/min/1.73 m2), and the renal outcomes with end-stage renal disease (ESRD; p = 0.003), ESRD and/or eGFR decrease of >30% (p = 0.033) and ESRD and/or eGFR decrease of >50% (p = 0.046) occurred significantly more in group 3. …”

Trichopsistides A and B: Two Highly Oxygenated Pentacyclic Polyketides with Promising Inhibitory Effects on the NF-κB Signaling Pathway from the Fungus <i>Trichoderma koningiopsis<... by Li Feng (77923)

“…Two highly oxygenated pentacyclic polyketides with two new carbon skeletons, trichopsistide A (<b>1</b>) and trichopsistide B (<b>2</b>), were isolated from the plant endophyte <i>Trichoderma koningiopsis</i> WZ-196 derived from the leaf of <i>Rubia podantha</i> Diels. …”

Identification of ALDH6A1 as a Potential Molecular Signature in Hepatocellular Carcinoma via Quantitative Profiling of the Mitochondrial Proteome by Heon Shin (4559110)

“…Surprisingly, in ALDH6A1-O/E cells, NO was decreased nearly 50% but ROS was increased at a similar level, while the former was restored by treatment with <i>S</i>-nitroso-<i>N</i>-acetyl-penicillamine. …”

Discovery of PMSA Derivative <b>11</b> as a Novel Lead Compound for Therapeutic Treatment of Osteoporosis <i>In Vitro</i> and <i>In Vivo</i> by Zhihao Chen (513264)

“…Additionally, <b>11</b> blocked the formation of F-action belts and bone resorption in a concentration-dependent manner. Mechanistically, <b>11</b> decreased the expression of genes required for osteoclastogenesis by blocking NFATc1 translocation from the cytoplasm to nucleus. …”

Penidaleodiolides A and B, Cage-Like Polyketides with Neurotransmission-Regulating Activity from the Soil Fungus <i>Penicillium daleae</i> L3SO by Qing-Yuan Wang (11571890)

“…The hypothetical biosynthetic pathways for <b>1</b> and <b>2</b> were postulated and were supported by CRISPR/Cas9 genome editing results. Penidaleodiolide A (<b>1</b>) showed a significant inhibitory effect on the action potentials of murine hippocampal basket neurons and decreased the frequency of spontaneous excitatory postsynaptic currents in a concentration-dependent manner (the inhibition ratios were 0.30 ± 0.02 for 1 μM, 0.37 ± 0.03 for 10 μM, and 0.50 ± 0.07 for 20 μM) while being devoid of cytotoxicity against the nerve cells.…”

Demographic information of focus group participants. by Katie J. Shillington (16557695)

Inhibition of <i>in vitro</i> and <i>in vivo</i> inflammatory responses in rats by p30A peptide. by Jérôme Rambert (46851)

“…(D) Histopathologic analysis confirm p30A ability to decrease all components of AIA lesions: pannus formation and inflammation of the synovium (P), deformity of joint and bones (asterix), bone remodeling and destruction (arrowhead), bone neoformation (arrows) and cartilage destruction.…”

The prosocial behaviour and kindness of participants over time. by Katie J. Shillington (16557695)

Generation of CYP5122A1 half knock-outs. by Smriti Verma (204089)

“…<b>D:</b> Western blot analysis of cell lysates from WT and HKO parasites probed with anti-CYP5122A1 antibody showing decreased level of CYP5122A1 protein in the HKO parasites. …”

Flow diagram depicting shift in prosocial behaviour over the pandemic. by Katie J. Shillington (16557695)

Examples of participants’ prosocial behaviour described during focus groups (n = 42). by Katie J. Shillington (16557695)