EBNA3C down-regulated RASSF1A mRNA expression by enhancing RASSF1A promoter methylation. by Shengwei Zhang (321384)

“…(I) The methylation levels of the RASSF1A promoter was specifically increased in BJAB7, BJAB10, LCL1, and LCL2 cells. 5 million BJAB, BJAB7, BJAB10, LCL1, and LCL2 cells were harvested and genomic DNA was extracted as described in materials and methods. 1 μg genomic DNA was used for bisulfite conversion and purification via the EZ DNA Methylation Gold Kit. 100 ng and 50 ng bisulfite-modified DNA was used in 15 μl methylation-specific PCR (MSP) reaction to amplify methylated (M) and unmethylated (U) DNA fragments. …”

Effectiveness of a Closed-System Transfer Device in Reducing Surface Contamination in a New Antineoplastic Drug-Compounding Unit: A Prospective, Controlled, Parallel Study by Nicolas Simon (1835062)

“…Gemcitabine amounts were 220.6 and 283.6 ng for the Standard and Phaseal isolators (NS), and ganciclovir amounts were 179.9 and 2.4 ng (p<0.0001).…”

DataSheet1_Dynamics of Dietary Mercury Determined by Mercury Speciation and Isotopic Composition in Dicentrarchus labrax.docx by Marianna Pinzone (8113781)

“…Each group was fed with pellets containing environmentally relevant MeHg concentrations (Control, 200 and 500 ng g⁻¹ dw). We monitored the evolution of MeHg and iHg concentrations as well as Hg isotopic values in liver and muscle. …”

A Single Arm Pilot Study of Effects of Berberine on the Menstrual Pattern, Ovulation Rate, Hormonal and Metabolic Profiles in Anovulatory Chinese Women with Polycystic Ovary Syndro... by Lin Li (28817)

“…The ovulation rate was 25.0% over four months in the whole group, 22.5% in the normal weight group and 31.0% in the overweight/obese group. …”

DataSheet_2_Nitrification and denitrification processes in a zero-water exchange aquaculture system: characteristics of the microbial community and potential rates.pdf by Shuhui Niu (15351196)

“…<p>​The zero-water exchange aquaculture has been identified as a promising method of farming to decrease the environment pressure of aquaculture and to increase profits. …”

(-)-Oleocanthal treatment inhibits HGF-induced Met activation, stabilizes the epithelial phenotype, and reduces mesenchymal phenotype in breast cancer cells. by Mohamed R. Akl (566987)

“…Cells were then washed twice with PBS and starved in control or treatment medium containing 0.5% FBS for 72 h and stimulated with 100 ng/ml human recombinant HGF for 10 min before cell lysis. …”

DataSheet_1_Nitrification and denitrification processes in a zero-water exchange aquaculture system: characteristics of the microbial community and potential rates.docx by Shuhui Niu (15351196)

“…<p>​The zero-water exchange aquaculture has been identified as a promising method of farming to decrease the environment pressure of aquaculture and to increase profits. …”

Th17 level is higher in severe and poor-responder patients, Treg level is higher in responder patients. by Takuya Furuhashi (276955)

“…Horizontal bar indicates mean value. (<b>B</b>) Psoriasis patients were grouped in each treatment group achieving 50%, 75% improvement PASI score from baseline (PASI 50, PASI 75). …”

Intense reelin IR neurons synthesize reelin whereas punctate reelin IR neurons are characterized by the presence of receptor-bound reelin. by Cecilia Gonzalez Campo (264260)

“…GST-RAP was used at 25, 40 and 50 µg/ml. A significant decrease of punctate reelin IR was observed with 40 and 50 µg/ml of GST-RAP (4.5±1.5% and 3.1±0.7%; n = 3 and 3) whereas no effect was detected with a concentration of 25 µg/ml compared to untreated (22.2±1.4% and 21.3±2.2%; n = 3 and 3; F_(3,8) = 45.7, ***P<0.001). …”

Silence of ST6GAL1 gene enhances the chemosensitivity of K562/ADR cell both in vitro and in vivo. by Hongye Ma (424073)

“…IC₅₀ represents the drug concentration producing 50% decrease of cell growth. …”

Transcriptional expression of Nrf1 and its reporter is unaffected by SREBP1 or rapamycin. by Keli Liu (5937368)

“…<p>(A to D) Two cell lines of HepG2 (<i>A</i>, <i>B</i>) and L7702 (<i>C</i>, <i>D</i>), that had been transfected with: (<i>A</i>, <i>C</i>) siNC (a negative control) or siSREBP1; (<i>B</i>, <i>D</i>) a pSREBP1 expression construct or empty plasmid, were subjected to real-time qPCR analysis of mRNA expression levels of <i>SREBP1</i> and <i>Nrf1</i> (n = 3×3; with significant decreases (*, <i>p</i><0.01), significant increases ($, <i>p</i><0.01), or no significances (NS)). …”

Decline in SHP2 leads to increases in phospho-p38 to total p38 ratio, nuclear MITF, GPNMB promoter activity, and GPNMB in HepG2 cells. by Sumit Bhattacharyya (14205)

“…Increase was greatest following CASHP2, increasing to 30.9 ± 1.7 ng/mg protein from control level of 5.13 ± 0.13 ng/mg protein. …”

Involvement of p38MAPK activation in IL-17A-mediated hypercontractility in primary cultured murine SI SMCs. by Hirotada Akiho (559455)

“…RGS4 activity was evaluated by Celaview analysis as described in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0092960#pone-0092960-g005" target="_blank">Fig. 5D</a> (n = 4). Numerical data represent means ± s.e.m. …”

Efficacy and selectivity of the shSNP <i>in vitro</i>. by Valérie Drouet (3179907)

“…The mismatched shRNA conditions were not significantly different from the control condition except for 50T+sh50C (**P<0.01), 67T+sh67C and 67C+sh67T (***P<0.001) and they were all significantly different from the matched shRNA conditions showing the selectivity of this approach <i>in vitro</i> (sh39A, sh39C, sh67C (***P<0.001), sh60G (**P<0.01), sh50C, sh50T, sh60A and sh67T (*P<0.05). …”

Involvement of mitochondrial pathway in AG–4 induced apoptosis. by Deepak Kumar (63095)

“…Results are expressed as IC₅₀ (mean ± SEM) from three independent experiments (***p<0.001, compared to only AG–4 treated cells). …”

Supplementary Material for: A New Era in the Management of Cardiorenal Syndrome: The Importance of Cardiorenal Units. by León-Román J. (20602337)

“…A total of 45 (83%) and 16 (30%) patients completed follow-up in the CRU at 6 and 12 months, respectively. The mean age was 70 years±1.6, and 65% were men. Almost 50% of patients had ischemic heart disease-related HF. …”

Efficacy and safety of a single radiofrequency ablation of solid benign non-functioning thyroid nodules by Roberto Cesareo (4676131)

Datasheet1_Outcomes among patients undergoing transcatheter aortic valve replacement with very low baseline gradients.docx by Faisal Rahman (11048519)

“…At baseline, <30% of VLG patients had an excellent or good (50–100) KCCQ-12, whereas more than 75% and 50% had an excellent or good KCCQ-12 at 30-day and 1-year follow-up, respectively.…”

Activity coupling between V2 and the CPu. by Anett J. Nagy (5447606)

“…<p>(A) Experimental schematics showing the simultaneous recording of the LFPs and SUA in both the V2 and the dorsomedial CPu. (B) Mean raw spectra of the V2 (left) and CPu (right) are almost identical when the animals are running in both the uniformly gray (blue lines) and the striped (red) environments (mean power spectra of <i>N</i> = 30 and 175 LFP sessions, respectively). …”

Period of latency, progression and duration of blockade of epidural anesthesia with lidocaine, bupivacaine or its association in dogs by S.J. Ronchi (8143470)