Mangiferin Decreases Plasma Free Fatty Acids through Promoting Its Catabolism in Liver by Activation of AMPK by Yucun Niu (186774)

“…Wistar rats were fed a high-fat diet and administered mangiferin simultaneously for 6 weeks. Mangiferin (50, 100, 150 mg/kg BW) decreased dose-dependently FFA and triglycerides (TG) levels in plasma, and their accumulations in liver, but increased the β-hydroxybutyrate levels in both plasma and liver of hyperlipidemic rats. …”

Data from the behavioural experiments described in the paper: Decreased olfactory discrimination is associated with impulsivity in healthy volunteers by Aleksandra Herman (4465258)

“…<b>Data for paper appearing in Scientific Reports</b><div><br></div><div>Excel workbooks containing data collected and analysed in the paper: "Decreased olfactory discrimination is associated with impulsivity in healthy volunteers". …”

miR-105 results in decreased Cdk6 expression at both the mRNA and protein levels. by D. Rice Honeywell (442714)

“…Blots were reprobed for levels of β-actin as a loading control for total protein. We observed a significant decrease in both Cdk6 mRNA and protein expression in miR-105 overexpressing as compared to control mimic-transfected PC3 cells. …”

Loss of Slfn3 induces a gender-dependent repair vulnerability after 50% bowel resection by Emilie DeKrey (9389738)

Dynamic characteristics of (A) FIB and (B) PCT between the survival and deceased groups of SFTS patients with HLH. by Bo Zhang (6559)

Lysine 50 of Tat regulates expression of C5, CRLF2, APBA1, and BDNF genes. by Loreto Carvallo (4167607)

“…Quantification is expressed in arbitrary units, relative to THP-1-luciferase set to 1, and target mRNA levels were normalized to 18S expression using the method of Pfaffl. The K50ATat-Flag mutant decreased Tat-Flag complex mediated C5 expression, and its expression is similar to the control at 24 hours. …”

Disrupting Glycolysis-promoting Genes Extends <i>C</i>. <i>elegans</i> Healthspan, Whereas High Glucose and Gluconeogenic Gene Disruptions Shorten Healthspan. by Brian Onken (86790)

“…<i>elegans</i> ORF designations indicated). We note that, in our hands, disruption of C50F4.2 (<i>pfk-1</i>.…”

Urine cytokines levels and renal histology (n = 69). by Pintip Ngamjanyaporn (5618255)

μCT analysis of organotypic cultured embryonic femurs (E13) in basal and TGF-β3 conditions. by Emma L. Smith (716897)

“…^#<i>P</i> < 0.05, ^###<i>P</i> < 0.001 increase/decrease in μCT bone morphometric indices of TGF-β3 (5 ng/mL and 15 ng/mL) cultured embryonic femurs compared to basal cultured embryonic femurs. …”

Heart rate variability in type 2 diabetes mellitus: A systematic review and meta–analysis by Thomas Benichou (5047928)

“…Measurements of HRV retieved were: RR–intervals (or Normal to Normal intervals—NN), standard deviation of RR intervals (SDNN), percetange of adjacent NN intervals differing by more than 50 milliseconds (pNN50), square root of the mean squared difference of successive RR intervals (RMSSD), total power, Low Frequency (LF), High Frequency (HF) and LF/HF ratio, as per Task Force recommendations.…”

The p50 Subunit of NF-κB Orchestrates Dendritic Cell Lifespan and Activation of Adaptive Immunity by Paola Larghi (131929)

“…A key factor in this equilibrium is the lifespan of DC, as its reduction restrains antigen availability leading to termination of immune responses. Here we show that lipopolysaccharide-driven DC maturation is paralleled by increased nuclear levels of p50 NF-κB, an event associated with DC apoptosis. …”

μCT analysis of organotypic cultured embryonic femurs (E11) in basal and TGF-β3 conditions. by Emma L. Smith (716897)

“…<i>***P</i> < 0.01 increase in μCT bone morphometric indices of basal cultured femurs compared to non-cultured femurs ^#<i>P</i> < 0.05, ^###<i>P</i> < 0.001 increase/decrease in μCT bone morphometric indices of TGF-β3 (5 ng/mL and 15 ng/ml) cultured embryonic femurs compared to basal cultured embryonic femurs. …”

Identification of Genes that Elicit Disuse Muscle Atrophy via the Transcription Factors p50 and Bcl-3 by Chia-Ling Wu (114083)

“…To identify direct targets of p50 and Bcl-3 we performed chromatin immunoprecipitation of selected genes previously shown to have roles in atrophy. …”

Inhibition of pan- and HDAC isoform activities. by Mira Jung (1277502)

“…Cellular growth inhibition studies show that SP-1-303 differentially inhibits growth of estrogen receptor positive breast cancer (ER+ BC) cells with effective growth inhibition concentrations (EC₅₀) for MCF-7 and T47D cells ranging from 0.32 to 0.34 μM, compared to 1.2–2.5 μM for triple negative breast cancer cells, and ~12 μM for normal breast epithelial cells. …”

Down-regulation of pol III activity in hypoxia is not due to a decrease in the abundance of TFIIIB, TFIIIC or pol III subunits by Isabelle Ernens (13462)

Pretreatment of β-cells with recombinant CXCL12 improves viability and induces a decrease in PARP-1 activity. by Nevena Grdović (394542)

Benchmarking DEWÄKSS on a predefined benchmark test [29]. by Andreas Tjärnberg (3438332)

IFNγ increases PRL immunoreactivity in the hair follicle, whilst TNFα decreases follicular PRL immunoreactivity. by Ewan A. Langan (405804)

“…Results were pooled from 3 ♀ subjects (Aged 44–68), 14–16 HFs per group in total. In contrast, TNFα 5 ng/ml significantly decreased PRL IR (E). PRL IR is shown in (F) control hair follicles and those treated with (G) TNFα 0.5 ng/ml and (H) TNFα 5 ng/ml. …”

NKCC1 knockdown decreases the net contractile moment and projected area in primary human GB cell lines. by Tomas Garzon-Muvdi (168470)

Exposure to EtBr decreases mtRNA in rat striatal co-cultures, purified neuronal cultures, and astrocytes. by Emily Booth Warren (4276333)

“…Error bars reflect delta-method propagated +/-SEM, with level of significance determined following Dunn’s post-hoc test. 2D[<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0190456#pone.0190456.ref005" target="_blank">5</a>] = 5ng/ml EtBr for 2 days, 4D[<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0190456#pone.0190456.ref005" target="_blank">5</a>] = 5ng/ml EtBr for 4 days, 2D[<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0190456#pone.0190456.ref050" target="_blank">50</a>] = 50ng/ml EtBr for 2 days, 4D[<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0190456#pone.0190456.ref050" target="_blank">50</a>] = 50ng/ml EtBr for 4 days. …”