Penidaleodiolides A and B, Cage-Like Polyketides with Neurotransmission-Regulating Activity from the Soil Fungus <i>Penicillium daleae</i> L3SO by Qing-Yuan Wang (11571890)

“…The hypothetical biosynthetic pathways for <b>1</b> and <b>2</b> were postulated and were supported by CRISPR/Cas9 genome editing results. Penidaleodiolide A (<b>1</b>) showed a significant inhibitory effect on the action potentials of murine hippocampal basket neurons and decreased the frequency of spontaneous excitatory postsynaptic currents in a concentration-dependent manner (the inhibition ratios were 0.30 ± 0.02 for 1 μM, 0.37 ± 0.03 for 10 μM, and 0.50 ± 0.07 for 20 μM) while being devoid of cytotoxicity against the nerve cells.…”

Neutrophil Gelatinase Associated Lipocalin Is an Early and Accurate Biomarker of Graft Function and Tissue Regeneration in Kidney Transplantation from Extended Criteria Donors by Vincenzo Cantaluppi (92814)

“…In the non DGF group, NGAL discriminated between slow or immediate graft function and decreased more rapidly than serum creatinine. NGAL increased after Tac introduction, suggesting a role as marker of drug toxicity. …”

Dietary or gavaged TU-100 and the ginger component decrease enteropooling stimulated by anti-CD3 antibody treatment in specified pathogen free (SPF) and germ free (GF) C57Bl6 mice. by Nobuhiro Ueno (346397)

Flow diagram depicting shift in prosocial behaviour over the pandemic. by Katie J. Shillington (16557695)

Examples of participants’ prosocial behaviour described during focus groups (n = 42). by Katie J. Shillington (16557695)

Behavioral evaluations in 5 dpf morphants showing the reduction of swimming ability. by De-Fen Shih (441898)

“…<p>Both total distance and average velocity in swimming behavior were decreased in <i>ddc</i> morphants. (<b>A</b>) Swimming routes of a 5 dpf larva with injection of none, 1x injection buffer, 5 ng tMO1,100 pg mRNA and 5ng tMO1 and 100 pg <i>ddc</i> mRNA mixture to rescue, respectively. …”

Knockdown of CRT suppressed VEGF-A expression and mRNA stability through ARE in AGS cells. by Po-Chu Lee (438366)

“…VEGF-A mRNA was significantly less stable in the CRT-knockdown cells with lower half-life and 50% mRNA remaining time. …”

Participants’ prosocial behaviour over time. by Katie J. Shillington (16557695)

Participants’ engagement in deliberate acts of kindness over time. by Katie J. Shillington (16557695)

Participants’ view of kindness as crucial over time. by Katie J. Shillington (16557695)

Participants’ awareness of kindness around them over time. by Katie J. Shillington (16557695)

Analysis of Research Activity in Gastroenterology: Pancreatitis Is in Real Danger - Fig 2 by Andrea Szentesi (3239193)

Effects of the selective TrkA agonist gambogic amide on pigmentation and growth of human hair follicles <i>in vitro</i> - Fig 4 by Remo Campiche (3714208)

“…Hair follicles treated with lower concentrations of Gambogic Amide kept their anagen-like appearance. Bars = 50 μm. <b>E: Immunohistochemical quantification of melanocytes with p16, a marker for mature and senescent melanocytes</b>. …”

QS signaling over <i>V. cholerae</i> biofilm development. by Grace E. Johnson (21376787)

“…<p><b>(A)</b> Average per-cell-volume <i>qrr</i>4 (<i>mNG</i>) and <i>hapR</i> fluorescence signal across <i>n </i>= 10 replicate WT <i>V. cholerae</i> biofilms as a function of the average biofilm biovolume. …”

Box plot displaying the distributions of the deconvolution derived proportions of cell types. by Arttu Autio-Kimura (20454681)

Fig 3 - by Belinda Kweka (9931483)

“…Compared to those without G6PD deficiency, heterozygous females had decreased odds of PD/DM diagnosis (adjusted OR 0.47, 95% CI: 0.22, 0.99, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0244782#pone.0244782.t003" target="_blank">Table 3</a>). …”

Quantification of fasting glucose, random glucose, and insulin levels. by Jessica C. M. Hui (20370522)

Demographic information of survey participants. by Katie J. Shillington (16557695)

Cell type-specific expression of <i>mif</i>, <i>cd74a</i>, and <i>cd74b</i>. by Safia A. Essien (20108379)

A Decomposition analysis of iNTS change in incidence by SDI, 1990 to 2021. Fig 6B. SDI-related health inequality regression for the incidence rate of iNTS worldwide, 1990 and 2021. by Yunjuan He (7107446)