Peptides of AnxA2 R1 domain interfere with the PCSK9≡LDLR interaction. by Nabil G. Seidah (148050)

“…The AlphaScreen luminescence signal was measured at 580 nm emission wavelength. The competition of AnxA2 peptides with the PCSK9≡LDLR interaction was revealed by a decrease in luminescence signal and demonstrated that the longest AnxA2 peptide (aa 25–97) inhibits binding of PCSK9 to LDLR with an IC₅₀ of 0.6 µM. …”

Tryptophan end-tagging confers antifungal activity to a tick-derived antimicrobial peptide by Court Chiramba (19114972)

“…Although reduced, Os-C(W₅) retains some antibiofilm activity in RPMI-1640 supplemented with 50% foetal bovine serum and in a synthetic wound medium.…”

(A, B) The processes of DNA synthesis and maintenance of insulin content do not occur simultaneously. by Nidhi Rohatgi (409215)

“…(<b>C</b>) MSDC-0160 decreases Wnt signaling pathway by blocking β-catenin nuclear translocation. …”

S1P inhibits invasion and affects expression, secretion and activity of MMP2 and MMP9 in C643 cells. by Muhammad Yasir Asghar (423105)

S1P inhibits invasion and affects expression, secretion and activity of MMP2 and MMP9 in FTC-133 cells. by Muhammad Yasir Asghar (423105)

Development-specific <i>cyc</i> downregulation in <i>Pdf</i>+ cells prevents sLN_v fasciculation. by Grace Biondi (19924067)

Subclinical Left Atrial and Ventricular Dysfunction in Acromegaly Patients: A Speckle Tracking Echocardiography Study by Hasan Koca (10375963)

Efficacy and safety of a single radiofrequency ablation of solid benign non-functioning thyroid nodules by Roberto Cesareo (4676131)

Diastolic Left Ventricular Function in Relation to Urinary and Serum Collagen Biomarkers in a General Population by Zhen-Yu Zhang (458621)

“…We randomly recruited 782 Flemish (51.3% women; 50.5 years). We assessed diastolic LV function from the early and late diastolic peak velocities of the transmitral blood flow and of the mitral annulus. …”

Fluorescence time-lapse imaging of a single GPR3-HT-expressing CGN. by Tatsuhiro Miyagi (847543)

“…<p>(A-B) The CGNs were transfected with the pGPR3-HT expression vector and were plated onto 0.03% PEI-coated plates. …”

Toxic activity of AS56 on the larval feeding behavior of <i>S. exigua.</i> by Niayesh Shahmohammadi (21262234)

“…<p>(A) Median lethal concentration (LC50) and median lethal time (LT50) of AS56 across various developmental stages (L1, L3, and L5) of S. exigua using the leaf-dipping method. …”

(A) Schematic presentation of the human AID protein sequence along with the positions of the lysine residues mutated in the various constructs by Said Aoufouchi (49316)

“…(D) Stable BL2 clones expressing the indicated AID-EGFP lysine mutants, WT-AID-EGFP, or mutNLS-AID-EGFP were incubated with cycloheximide (CHX, 50 μg/ml) and LMB (10 ng/ml). The decay of the protein was followed by the decrease in fluorescence intensity. …”

Severity of anaemia status among pregnant women. by Donatus Nbonibe Abaane (15909683)

“…At 36 weeks, AIP prevalence was 44.8% (95%CI:39.2, 50.4) using a cut-off of 11.0g/dl. At p<0.05, registering after the first trimester (AOR = 1.87, 95%CI: 1.17, 2.98, P = 0.009) and at a regional hospital (AOR = 2.25, 95%CI: 1.02, 4.98, P = 0.044) were associated with increased odds of AIP but registering at a private hospital (AOR = 0.32, 95%CI: 0.11, 0.92, P = 0.035) was associated with decreased odds of AIP at booking. …”

Effects of bortezomib on OATP1B1-mediated [³H]pitavastatin and [³H]E₂17βG transport in HEK293-OATP1B1 cells and on [³H]pitavastatin accu... by Khondoker Alam (1443499)

Maternal Transfer of 2‑Ethylhexyl Diphenyl Phosphate Leads to Developmental Toxicity Possibly by Blocking the Retinoic Acid Receptor and Retinoic X Receptor in Japanese Medaka (Ory... by Yu Li (183836)

“…2-Ethylhexyl diphenyl phosphate (EHDPP) has been detected in wild fish with high concentrations, which may pose a risk in the embryo development considering its potential maternal transfer. …”

Expected changes in obesity after reformulation to reduce added sugars in beverages: A modeling study by Ana Basto-Abreu (5823866)

“…On average, 12.6% of the TEI was contributed by added sugars; we defined a 50% reduction in added sugars in SSBs over 10 years as a reformulation target. …”

Fiber cell ultrastructure near the bow region up to a depth of 300 μm. by M. Joseph Costello (3043893)

“…Note the nucleus is slightly irregular in shape but otherwise normal in appearance with portions of a nucleolus visible. Autophagosomes with double membranes are indicated (yellow arrows), although they decrease in number corresponding to a decrease in membranous organelles in the cytoplasm through this region. …”

The efficacy of topical 8% capsaicin patches for the treatment of postsurgical neuropathic pain: a systematic review by Brandon Goodwin (20328988)

“…All studies that investigated neuropathic pain area denote a decrease in pain size, with some denoting a continued reduction with subsequent application.…”

Prenatal medication use in a prospective pregnancy cohort by pre-pregnancy obesity status by Yassaman Vafai (10294851)

“…A total of 17 classes of medications were identified. …”

DataSheet_1_A phase I trial of SON-1010, a tumor-targeted, interleukin-12-linked, albumin-binding cytokine, shows favorable pharmacokinetics, pharmacodynamics, and safety in health... by Richard T. Kenney (15289313)

“…</p>Methods<p>SB102 (NCT05408572) focused on safety, tolerability, pharmacokinetic (PK), and pharmacodynamic (PD) endpoints. SON-1010 at 50-300 ng/kg or placebo administered subcutaneously on day 1 was studied at a ratio of 6:2, starting with two sentinels; participants were followed through day 29. …”