Effects of insulin and IGF-I stimulation on the expression levels of bisecting GlcNAc <i>N</i>-glycans, in general and specifically on E-cadherin. by Julio Cesar Madureira de-Freitas-Junior (489189)

“…MDA-MB-435+E-cad cells stimulated with insulin (100 ng/mL) and IGF-I (50 ng/mL) showed a significant decrease of the overall levels of bisecting GlcNAc N-glycans. …”

DataSheet_1_Gold complex compounds that inhibit drug-resistant Staphylococcus aureus by targeting thioredoxin reductase.pdf by Nagendran Tharmalingam (6408629)

“…In an S. aureus enzymatic assay, AU1 inhibited TrxR enzymatic activity in a dose-dependent manner causing a decrease in intracellular free thiols. …”

Table_1_Habenular Involvement in Response to Subcallosal Cingulate Deep Brain Stimulation for Depression.DOCX by Gavin J. B. Elias (12044813)

“…Clinical response to treatment (≥50% decrease in HAMD-17 from baseline to 12 months post-operation) was significantly associated with longitudinal Hb volume change: responders tended to have increased Hb volume over time, while non-responders showed decreased Hb volume (t = 2.4, p = 0.021). …”

Image_1_NM23-H1 Expression of Head and Neck Squamous Cell Carcinoma in Association With the Response to Irradiation.pdf by Yi-Fen Wang (531758)

“…Knockdown of NM23-H1 decreased the radio-sensitivity of SAS cells, possibly associated with a decrease in the radiation-induced G2/M-phase accumulation and upregulation of cyclin B1. …”

Supplementary Material for: Burden of Neurological disorders in children and adolescents (<20 years old) in North Africa and the Middle East (NAME) from 1990 to 2021 by figshare admin karger (2628495)

“…Idiopathic epilepsy remained a leading cause of mortality, although it had a decrease of -50.9% in YLLs compared to 1990. …”

DataSheet_2_Overfishing Increases the Carbon Footprint of Seafood Production From Small-Scale Fisheries.csv by Erica M. Ferrer (12455388)

“…<p>Small-scale fisheries (SSFs) and the foods they produce are extremely important, contributing 25–50% of global seafood landed for direct consumption. …”

Pyrvinium inhibits Wnt signaling. by Sarika Saraswati (236578)

“…<p>(<b>A</b>) Pyrvinium inhibits TOPflash activation with an EC₅₀ of ∼10 nM in contrast to the structurally related compound VU-WS211. …”

SS- and AGEs-induced simultaneous increases in proliferation and apoptosis of VSMCs are closely associated with selective activation of three members the MAPK subfamily. by Suning Ping (172755)

“…<b>(A, E, I, M)</b> Either SS or AGEs could induce simultaneous increases in proliferation (Ki-67 positive, red, arrows) and apoptosis (TUNEL positive, green, arrowheads), and combined stimulation with both had a synergistic effect. …”

VER-155008 abrogated viral protein synthesis pre-translationally in TREx BCBL1-RTA cells. by Belinda Baquero-Pérez (706834)

“…(C) Immunoblot analysis showing that reactivated cells treated with non-cytotoxic inhibitor concentrations (1 to 2.5 μM) for 24 h revealed a decrease in viral proteins compared with DMSO-treated samples while cellular proteins remained unaffected. …”

Lagged biodiversity recoveries. by Roberto Latorre (282007)

“…Notably, the figure illustrates cases where biodiversity loss is driven by reduced speciation rather than increased extinction (e.g., the event indicated by the arrow, where a prior burst of speciation reaching nearly 50% is followed by a sharp drop in speciation, while extinction rates remain nearly constant or even decrease). …”

Physiological and transcriptomic data for <i>sdc</i>, <i>dc</i> and <i>sdc/dc</i> mutants. by Diego H. Sanchez (230286)

“…Right: Relative mean aerial biomass as percentage of controls obtained from the data shown on the left, denoting a decrease of at least 30% in relative biomass after treatment of genetic backgrounds harboring the <i>sdc</i> mutation. …”

Spatial-temporal variation in litterfall in seasonally dry tropical forests in Northeastern Brazil by V. F. P. Araújo (7141901)

“…The inter- and intra-annual variation in litterfall production was positively correlated with precipitation and evapotranspiration rates, and four months after the highest precipitation rates, there was a marked decrease in litterfall occurred during the dry season. …”

Expression of MP does not interfere with the silencing pathway. by Hannes Vogler (272256)

“…In the presence of MP, the GFP siRNA levels are reduced by about 50% compared to the empty vector control, whereas dMP causes a slight increase. …”

DataSheet_2_Unveiling drug-tolerant and persister-like cells in Leishmania braziliensis lines derived from patients with cutaneous leishmaniasis.xlsx by Marlene Jara (774474)

“…</p>Results and discussion<p>We demonstrated in vitro that a variable proportion of cells remained viable, showing all the criteria of DT and not of DR: i) signatures of quiescence, under drug pressure: reduced proliferation and significant decrease of rDNA transcription; ii) reversibility of the phenotype: return to low IC₅₀ after removal of drug pressure; and iii) absence of significant genetic differences between exposed and unexposed lineages of each strain and absence of reported markers of DR. …”

Table 1_Preliminary clinical activity of TP-0903 in relapsed or refractory acute myeloid leukemia with FLT3-ITD mutations.docx by Bhavana Bhatnagar (11016429)

“…Three heavily treated relapsed/refractory AML patients with FLT3-ITD were treated with TP-0903 50 mg daily, on a phase 1b/2 clinical trial, for as long as disease response or clinical benefit was observed. …”

Effect of rotenone on the striatum, VTA, and SNc TH immunoreactivity. by Nian Xiong (218611)

“…The TH immunoreactivity on the ipsilateral side of the striatum was decreased by 66.4% (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0007878#pone-0007878-g004" target="_blank">Figure 4I–J</a>; *P<0.05, as compared to the contralateral side). …”

Image_1_Habenular Involvement in Response to Subcallosal Cingulate Deep Brain Stimulation for Depression.TIF by Gavin J. B. Elias (12044813)

“…Clinical response to treatment (≥50% decrease in HAMD-17 from baseline to 12 months post-operation) was significantly associated with longitudinal Hb volume change: responders tended to have increased Hb volume over time, while non-responders showed decreased Hb volume (t = 2.4, p = 0.021). …”

Data_Sheet_1_Cu5FeS4 Nanoparticles With Tunable Plasmon Resonances for Efficient Photothermal Therapy of Cancers.docx by Lei Yuan (713591)

“…After surface modification with polyethylene glycol (PEG), the CFS nanoparticles with a plasmon resonance absorption peak at 764 nm can serve as promising photothermal agents, showing good biocompatibility and excellent photothermal performance with a photothermal conversion efficiency of up to 50.5%, and are thus used for photothermal therapy of cancers under the irradiation of an 808-nm laser. …”

CM inhibits adhesion of U937s and adhesion molecule expression in PECs. by Shibani Pati (208746)

“…After gentle washing, bound cells were quantitatively and qualitatively assessed. <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0025171#pone-0025171-g002" target="_blank">Figure 2A</a> shows decreased binding of U937 (green dots) in CM treated cultures. …”

Antibodies of the PGT121 family compete with sCD4, but not PGV04, for binding to gp120 in solution and on the cell-surface. by Jean-Philippe Julien (135641)