Runx1 attenuates PM proliferation. by Kfir Baruch Umansky (783699)

“…(G) IF analysis of infected PM using anti- Runx1 and MHC Abs (scale bars, 50 μm and 20 μm for x200 or x630 magnification, respectively). …”

Increased Autophagy in <i>daf-2/</i>insulin/IGF Receptor Mutants Is Independent of the <i>daf-16</i>/FOXO and <i>pha-4</i>/FOXA Transcription Factors by Malene Hansen (10367)

“…The mean lifespan of <i>daf-2(e1370)</i> animals was shortened 12.5% by <i>pha-4</i> RNAi ([<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.0040024#pgen-0040024-b028" target="_blank">28</a>] and data not shown), and we measured an 11% decrease in puncta in <i>daf-2(e1370)</i> animals fed <i>pha-4</i> RNAi. …”

Requirement of viral DNA replication for sT-mediated late gene reporter activation in MCV reporter viral genomes. by Kyle Rapchak (13833941)

“…<b>(B)</b> Quantification of late gene-driven ZsG positive cells (top panel) and mean fluorescence intensity (bottom panel). Cells obtained from 6 independent transfections were analyzed by flow cytometry. sT deletion does not significantly decrease ZsG positive cells whereas introducing a mutation into the NCCR (MCVΔsT.L-ZsG_rep-) decreased percent positivity by 50%. …”

Ketamine reduces cell adhesion. by Claire E. Hills (452020)

“…<p>AFM-single-cell force spectroscopy was used to measure the detachment energy (fJoules) and maximum unbinding force (nN) required to uncouple two HK2 cells. The energy required to separate the cells; grey area in panel A (control cells), panel B (0.1 mg/mL Ketamine treated cells), panel C (0.5 mg/mL Ketamine treated cells), and panel D (1 mg/mL Ketamine treated cells), and maximum force of detachment (red circle) was measured. …”

Iron Supplementation and Mortality in Incident Dialysis Patients: An Observational Study by Emanuel Zitt (228284)

“…Increasing ferritin concentrations in patients with normal CRP were associated with a decreasing mortality, whereas in patients with elevated CRP values ferritin levels>800 ng/mL were linked with increased mortality.…”

The concentration dependence of toxicogenomic responses and the synergistic effects of low doses by Lixin Yang (41431)

“…</p><p></p> Embryos were exposed to decreasing concentrations of Cd (a, lane 1, 5 mg/l: lane 2, 2.5 mg/l; lane 3, 0.5 mg/l), or MeHg (b, lane 1, 60 μg/l; lane 2, 30 μg/l; lane 3, 6 μg/l) or TCDD (c, lane 1, 500 ng/l; lane 2, 250 ng/l; lane 3, 50 ng/l). …”

An early Env engineered to have weak, medium, or tight binding to CD4 becomes progressively more promiscuous in its use of primate CD4 receptors. by Cody J. Warren (563898)

“…Error bars are not plotted in instances in which the size of the error bar is less than the symbol size. IC₅₀ values are listed on each panel, for which the mean and SD values reflect the variation of the IC₅₀ calculations from two independent experiments. …”

TPMP inhibits mitochondrial respiration and increases glycolytic activity in intact C2C12 cells. by Moustafa Elkalaf (441286)

“…The inhibitory effect following TPMP treatment is demonstrated by a gradual dose-dependent decrease in cellular OCR. Data is expressed as the percentage of basal OCR (OCR%) and is presented as means ±95% CI, n = 4, measured in triplicate. …”

Low Cardiac Output Leads Hepatic Fibrosis in Right Heart Failure Model Rats by Yoshitaka Fujimoto (849634)

“…Hepatic fibrosis ratio and serum hyaluronic acid, an index of hepatic fibrosis, were significantly increased in the PAB group than those in the control group (7.8±1.7 and 1.0±0.2%, P<0.01, 76.2±27.5 and 32.7±7.5 ng/ml, P<0.01). Notably, the degree of hepatic fibrosis significantly correlated a decrease in CO. …”

<i>myh9</i> expression in the context of <i>apol1</i>/<i>APOL1</i> modulation. by Blair R. Anderson (765261)

“…Total RNA at 5 dpf or 3 dpf (<i>APOL1</i> G2/<i>atpif1α</i>-MO embryos did not survive to 5 dpf) was extracted and reverse-transcribed with random primers to obtain whole-embryo cDNA. …”

The RA and FGF/MAPK pathways control the AP patterning of <i>Ciona</i> tail epidermis. by Andrea Pasini (17809)

“…(<b>Q–T</b>): Epidermal expression of a dominant-negative form of the <i>Ciona</i> FGF receptor leads to the ectopic expression of <i>Ci-hox1</i> (arrowhead in Q) and to the loss or decrease of <i>Ci-hox12</i> (R), <i>Ci-wnt5</i> (S) and <i>Ci-fgf8/17/18</i> (T). …”

Supplementary Material for: Carpal Tunnel Surgery as Proxy for Dialysis-Related Amyloidosis: Results from the Japanese Society for Dialysis Therapy by Hoshino J. (4145806)

“…<b><i>Methods:</i></b> The cohort consisted of 166,237 patients on dialysis (mean age 66.1 ± 12.4 years; mean dialysis vintage 7.2 ± 6.4 years) who could be followed for a year between 2010 and 2011. …”

Fitness of the ligases and their relationships in crude evolutionary time. by Carolina Díaz Arenas (504034)

“…Populations where poly-A mutants (<i>e.g</i>., A27) are present in high frequency decrease in size, and are at risk of extinction, due to the low mean fitness value of the population, which keeps decreasing as adenylation tracks are extended. …”

(a) Western blot for G- and F-actin levels in MDA-MB 435 breast cancer cells cultured on fibronectin for 4 hours by Robert F. Klees (62686)

“…</p><p></p> Positive control (lanes 1 and 2) and ethanol control (lanes 3 and 4) were compared to cells in the presence of 36 ng/μl of compound 5 (lanes 5 and 6) and 36 ng/μl of compound 9 (lanes 7 and 8) by probing with an antibody for G-actin. …”

Neuronal complexity was greatly reduced by neuronal GALC depletion. by Conlan Kreher (13001753)

“…All data are presented as mean values +<i>/−</i> SEM. Two-way ANOVA with Tukey multiple comparison tests were used. …”

Table1_Positive short term effects of an integrative korean medicine treatment package for low back pain caused by motor vehicle accidents: A retrospective chart review of real – w... by Hye-Rin Park (13966560)

“…</p><p>Results A total of 50 patients, 30 males and 20 females, were included in the analysis. …”

Significant Reductions in Mortality in Hospitalized Patients with Systemic Lupus Erythematosus in Washington State from 2003 to 2011 by Louisa B Goss (757328)

“…</p><p>Results</p><p>There were a total of 18,905 patients in this study with a diagnostic code for lupus. The mean age of the group was 51.5 years (95% CI: 50.6-52.3) in 2003 and 51.3 years (95% CI: 50.6-52.0) in 2011. …”

Changes of the normalized volume V/V₀ in glioblastoma cell lines in response to sucrose- and inositol-substituted solutions of different osmolalities (LHS and RHS column... by Simon Memmel (518138)

“…Each data point represents the mean ± SE of 50–120 individual cells. Continuous curves in <i>A</i> show best least-square fits of the Lúcio-model <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0087052#pone.0087052-Lcio1" target="_blank">[50]</a> to the data. …”

Involvement of CFTR-mediated HCO₃⁻ transport in FSH-stimulated cAMP production and CREB regulation. by Wen Ming Xu (221689)

“…Adult rat germ cell (GC) sample shows predominatly exression of 50 kD, with another unidentified band. (<b>C</b>) Effect of HCO₃⁻, CFTR and sAC inhibitors on 50 ng FSH-stimulated cAMP production, with presence of 25 mM HCO₃⁻ potentiating FSH-stimulated cAMP production in Sertoli cells, which is abolished by 10 µM CFTRinh172 and 10 µM sAC inhibitor KH7. …”

Injection of PGE₂ reversed the immunosuppression induced by RNA interference (RNAi) of POX-F (A) and POX-H (B). by Jiyeong Park (626261)

“…<p>Immunosuppression was recorded as decreased nodule formation induced by injection of dsRNA, in which ‘dsPOX-F’ specific to POX-F or dsPOX-H specific to POX-H, was injected in a dose of 500 ng per larva and subsequently incubated for 48 h at 25°C. …”