Flow chart for patients inclusion. by Haruka Imai (3703819)

“…Following this, antibiotic prescription was associated with a decreased 28-day mortality rate (2.3% vs. 3.6%) and in-hospital mortality rate (4.0% vs. 5.0%) compared with the control group. …”

The outcome measures in IPTW analysis. by Haruka Imai (3703819)

“…Following this, antibiotic prescription was associated with a decreased 28-day mortality rate (2.3% vs. 3.6%) and in-hospital mortality rate (4.0% vs. 5.0%) compared with the control group. …”

Locomotion and turning angle sizes of adult <i>D</i>. <i>melanogaster</i>, <i>D</i>. <i>simulans</i>, <i>D immigrans</i>, <i>D</i>. <i>subobscura</i> and <i>D pavani</i> in Petri d... by Jeannette Silva-López (16541854)

<i>F</i>. <i>oxysporum</i> f. sp. <i>albedinis</i> genome code for a large repertoire of secreted proteins. by Maryam Rafiqi (12647200)

Structure-Guided Discovery of Potent and Selective CLK2 Inhibitors for the Treatment of Knee Osteoarthritis by Yongqiang Sun (8226111)

“…CDC2-like kinase 2 (CLK2) could modulate Wnt signaling via alternative splicing of Wnt target genes and further affect bone differentiation, chondrocyte function, and inflammation, making CLK2 an attractive target for OA therapy. In this study, we designed and synthesized a series of highly potent CLK2 inhibitors based on <b>Indazole 1</b>. …”

Structure-Guided Discovery of Potent and Selective CLK2 Inhibitors for the Treatment of Knee Osteoarthritis by Yongqiang Sun (8226111)

“…CDC2-like kinase 2 (CLK2) could modulate Wnt signaling via alternative splicing of Wnt target genes and further affect bone differentiation, chondrocyte function, and inflammation, making CLK2 an attractive target for OA therapy. In this study, we designed and synthesized a series of highly potent CLK2 inhibitors based on <b>Indazole 1</b>. …”

Structure-Guided Discovery of Potent and Selective CLK2 Inhibitors for the Treatment of Knee Osteoarthritis by Yongqiang Sun (8226111)

“…CDC2-like kinase 2 (CLK2) could modulate Wnt signaling via alternative splicing of Wnt target genes and further affect bone differentiation, chondrocyte function, and inflammation, making CLK2 an attractive target for OA therapy. In this study, we designed and synthesized a series of highly potent CLK2 inhibitors based on <b>Indazole 1</b>. …”

Structure-Guided Discovery of Potent and Selective CLK2 Inhibitors for the Treatment of Knee Osteoarthritis by Yongqiang Sun (8226111)

“…CDC2-like kinase 2 (CLK2) could modulate Wnt signaling via alternative splicing of Wnt target genes and further affect bone differentiation, chondrocyte function, and inflammation, making CLK2 an attractive target for OA therapy. In this study, we designed and synthesized a series of highly potent CLK2 inhibitors based on <b>Indazole 1</b>. …”

The initiation region/matrix attachment region (IR/MAR) increased the homogeneously staining region (HSR) elongation rate and decreased the frequency of micronuclei after elevation... by Shun-suke Tanaka (604228)

Number of bars of length greater than <i>ℓ</i> = 4000 in the barcodes obtained via the binary model (left) and the fuzzy binary model (right) as a function of <i>τ</i>. by Samir Chowdhury (5715338)

Mucin deglycosylase activity of ChiA2. by Moumita Mondal (632557)

“…A 50-fold decrease in the % area density of the spot was observed for ChiA2-treated rabbit mucin compared to the untreated one. …”

GCase activity is significantly decreased in the brain and liver of the homozygous <i>GBA1</i> D409V KI mouse model at 4, 8, and 12 months of age. by Nicole K. Polinski (10947787)

“…In whole brain homogenate (A,C) and liver homogenate (B,D), GCase activity is significantly decreased in the <i>GBA1</i> D409V KI homozygous (HOM) mice as compared to C57Bl/6 wild type (WT) mice (n = 7/group). …”

FldP decreases the H₂O₂-induced mutation frequency in <i>mutT</i>-deficient <i>P. aeruginosa</i>. by Alejandro J. Moyano (186752)

Triclosan Dioxygenase: A Novel Two-component Rieske Nonheme Iron Ring-hydroxylating Dioxygenase Initiates Triclosan Degradation by Yiran Yin (19144130)

“…The highest amino acid identity of TcsA and the large subunits of other dioxygenases in the same family was only 35.50%, indicating that TcsAB is a novel dioxygenase. …”

Anti TK1-sdAb-Fc antibodies elicit ADCC responses against NCI-H460 cells expressing mTK1. by Edwin J. Velazquez (8724405)

Gossypol prevents bleomycin-induced pulmonary fibrosis. by Jennifer L. Judge (5278415)

Gossypol prevents TGF-β1 induced fibronectin expression. by Jennifer L. Judge (5278415)

Gossypol treats bleomycin-induced fibronectin expression. by Jennifer L. Judge (5278415)

LDHA is increased in bleomycin-induced pulmonary fibrosis. by Jennifer L. Judge (5278415)

Gossypol inhibits LDH activity and prevents TGF-β1 expression and activation. by Jennifer L. Judge (5278415)