Minimal dataset. by Jennifer M. Kwan (3350321)

“…</p><p>Methods</p><p>We conducted a single center retrospective cohort study including 2165 cancer patients treated with ICIs between 2013 and 2020. …”

Role of the ACB domain and linker region in NMT2 activity. by Eric Soupene (64584)

“…Human NMT2 enzyme was added at a concentration of 50nM in the presence of 5μM C₁₄-CoA. …”

Defects in the conduction of somatosensory evoked potentials of median and tibial nerves in a healthy child and in H-ABC patient. by Jose R. Eguibar (8563227)

microRNA-34a-Mediated Down-Regulation of the Microglial-Enriched Triggering Receptor and Phagocytosis-Sensor TREM2 in Age-Related Macular Degeneration - Fig 6 by Surjyadipta Bhattacharjee (3181674)

“…After vacuum evaporation of HFIP, aliquoted peptide was re-suspended with DMSO to 5 mM and diluted to 5 μM into the cell culture media; <b>(B)</b> cells were treated with a scrambled miRNA-34a sequence (miRNA-34a-<b>sc</b>; 30 nM;, control, <b>a-d</b>, middle row); or <b>(C)</b> with an LNA-stabilized miRNA-34a (30 nM; miRNA-34a stressed; <b>a-d</b>; bottom row); treatments were for 24 hr before incubation with 5 uM of Aβ42 (made up as in [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0150211#pone.0150211.ref033" target="_blank">33</a>]) for another 24 hr before assay; MG cells were subsequently stained using a murine amyloid beta MABN10 (red fluorescence λ_max~650 nm; anti-Aβ antibody, clone W0-2; Millipore, Bellerica MA), a TREM-2 antibody (M-227): sc-48765 (green fluorescence; λ_max~510 nm; Santa Cruz, Santa Cruz CA) or DAPI nuclear stain (blue fluorescence; λ_max~470 nm) as in <b><a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0150211#pone.0150211.g003" target="_blank">Fig 3</a>;</b> arrows indicate Aβ42 uptake into MG cells; note decreased presence of TREM2 in miRNA-34a treated MG cells (bottom row, panel B) and decrease in ingested Aβ42 peptide within C8B4 cells (<b>C</b>; bottom row, panel <b>d</b>). …”

High-dose thiamine prevents brain lesions and prolongs survival of <i>Slc19a3</i>-deficient mice by Kaoru Suzuki (4217638)

“…To investigate the molecular mechanisms of neurodegeneration in SLC19A3 deficiency and whether administration of high-dose thiamine prevents neurodegeneration, we generated homozygous Slc19a3 E314Q knock-in (KI) mice harboring the mutation corresponding to the human SLC19A3 E320Q, which is associated with the severe form of THMD2. …”

Histological appearance and marker analysis in SV <i>vasa vasorum</i>. by Francesca Prandi (414376)

Hemodynamic and myocardial effects of EPO (open circles, n = 12) and vehicle control (closed circles, n = 12) in series <i>HS-50_BV</i>. by Vesna Borovnik-Lesjak (653673)

Aβ and 22C11 agonist decreased cholesterol uptake whereas the sAPP-derived peptide and SM-ϕ stimulated increased cholesterol uptake by Caco-2 cells. by Kendra L. Puig (334788)

SEM images of lattice scaffolds; A) 4 layers, B) 6 layers, C) 8 layers, D) 10 layers, and staggered scaffolds; E) 4 layers, F) 6 layers, G) 8 layers, H) 10 layers. by Zahra Yazdanpanah (10038944)

A complete set of mathematical model equations utilized in ILYCM software to develop S. <i>frugiperda</i> phenology for each life stage. by Marian Adan (16641634)

Fig 2 - by Muhammad Imran Nisar (10226212)

Individual serotype carriage rates over the study period. by Muhammad Imran Nisar (10226212)

The carriage rate of VT serotypes by number of doses of vaccine. by Muhammad Imran Nisar (10226212)

Serotype specific carriage rate from 2014–18 in Matiari, Pakistan. by Muhammad Imran Nisar (10226212)

Serotype-specific carriage rate by vaccination status. by Muhammad Imran Nisar (10226212)

Physio-Biochemical Composition and Untargeted Metabolomics of Cumin (<i>Cuminum cyminum</i> L.) Make It Promising Functional Food and Help in Mitigating Salinity Stress by Sonika Pandey (834285)

“…Relative water content remained unchanged up to 50 mM NaCl stress, and thereafter decreased significantly. …”

Colletopeptides A–D, Anti-inflammatory Cyclic Tridepsipeptides from the Plant Endophytic Fungus <i>Colletotrichum</i> sp. S8 by Li Feng (77923)

“…Four new hybrid peptide-polyketide cyclic tridepsipeptides, colletopeptides A–D (<b>1</b>–<b>4</b>), were isolated and characterized from the endophytic fungus <i>Colletotrichum</i> sp. …”

Colletopeptides A–D, Anti-inflammatory Cyclic Tridepsipeptides from the Plant Endophytic Fungus <i>Colletotrichum</i> sp. S8 by Li Feng (77923)

“…Four new hybrid peptide-polyketide cyclic tridepsipeptides, colletopeptides A–D (<b>1</b>–<b>4</b>), were isolated and characterized from the endophytic fungus <i>Colletotrichum</i> sp. …”

L1 overexpressing SENAs show increased neuronal differentiation and neurite outgrowth and decreased astrocytic differentiation after transplantation into the lesioned spinal cord w... by Yi-Fang Cui (227234)

Discovery of the Diphenyl 6‑Oxo-1,6-dihydropyridazine-3-carboxylate/carboxamide Analogue J27 for the Treatment of Acute Lung Injury and Sepsis by Targeting JNK2 and Inhibiting the... by Jing Liao (193197)

“…The optimal compound <b>J27</b> decreased the release of TNF-α and IL-6 in mouse and human cells J774A.1 and THP-1 (IL-6 IC₅₀ = 0.22 μM) through the NF-κB/MAPK pathway. …”