Simvastatin alters actin organization, cell morphology, and Rac1 activity in endothelial monolayers. by Marsha C. Lampi (845609)

“…Cell circularity, where a perfectly circular cell has a value of 1, decreases with increasing simvastatin concentration (n = 3, 50–54 cells per condition). …”

Classification of inactive compounds. by MohammedBashar Al-Qazzan (22439236)

“…</p><p>Results</p><p>Glyoxalase I inhibition revealed that 4-hydroxy-estradiol exhibited the highest efficacy with an IC₅₀ value of 0.226 µM. Trichostatin A demonstrated a significant anti-proliferation effect in colorectal cancer cells (CACO2, HCT116, SW620, HT29) with IC₅₀ values ranging from 14.0 µM to 27.0 µM. …”

I.p. injection of LPS induces inflammation in the brain A. by Fionä Caratis (12759506)

Analysis of protein interaction networks by STRING. by Masaya Nagaya (13851123)

ODE model fit is average of many DS simulations. by Apeksha Singh (8174256)

BEZ235 decreases p-AKT(Thr308), p-S6 ribosomal protein (Ser235/236), caspase-3, and retards the growth of ATC flank xenograft tumors without significant toxicity in nude mice. by Shu-Fu Lin (126854)

Structural and geometric features of connectivity modes. by Justine Y. Hansen (17041502)

Summary of the framework for the computation of the brain transition cost from EEG data. by Giacomo Barzon (19832364)

Population fraction of risk-deniers affects epidemics in synthetic networks models. by Valeria d’Andrea (12095838)

“…Each dot represents the average measure across 50 dynamical samples of a single network realization, box-plots show quartiles of distributions across 50 network realizations. …”

Effect of thalidomide on CUL5 and NEDD8 localization in control and si-transfected HUVEC at 24 hours after treatment. by Bryan Kunkler (5204327)

PDS5B is mutated in a case of familial CdLS. by Bin Zhang (64682)

“…The father, two affected children, and one unaffected child carry the R1292Q mutation (depicted by blackened symbol or small black dot). (E) The PDS5B(R1292Q) mutant has decreased DNA binding. EMSA using the T5-8-T5 AT-rich probe showed decreased DNA binding by mutant PDS5B compared to wildtype PDS5B. …”

Referenced studies with functional connectivity correlations with intensity and/or duration of chronic pain. by Peter A. Pahapill (8468607)

LTP modulates steady-state inactivation of A-type K⁺ currents. by Sung-Cherl Jung (261358)

“…Scale bars, 200 pA, 50 ms. The A-current available for activation at −60 mV was significantly decreased only in the neurons receiving paired stimulation 10 min after conditioning stimulation (a red arrow). …”

MAF1 protein expression by stage and tumor histology. by Stephanie Cabarcas-Petroski (9631636)

Binding of PregOBP56a to <i>N</i>-phenyl-1-naphthylamine (1-NPN) and potential ligands derived from chicken meat. by Yuko Ishida (104789)

“…Due to low binding to PregOBP56a, the IC₅₀ of other test competitors was not obtained.…”

The flow diagram of study selection. by Qianqian Liu (381114)

Shooting an Arrow against Convulsion: Novel Triazole-Grafted Benzenesulfonamide Derivatives as Carbonic Anhydrase II and VII Inhibitors by Mohamed A. Zeidan (21099628)

“…Evaluations of toxicity showed no neurotoxic effects and a high safety margin (LD₅₀ > 2000 mg/kg). …”

Shooting an Arrow against Convulsion: Novel Triazole-Grafted Benzenesulfonamide Derivatives as Carbonic Anhydrase II and VII Inhibitors by Mohamed A. Zeidan (21099628)

“…Evaluations of toxicity showed no neurotoxic effects and a high safety margin (LD₅₀ > 2000 mg/kg). …”

Shooting an Arrow against Convulsion: Novel Triazole-Grafted Benzenesulfonamide Derivatives as Carbonic Anhydrase II and VII Inhibitors by Mohamed A. Zeidan (21099628)

“…Evaluations of toxicity showed no neurotoxic effects and a high safety margin (LD₅₀ > 2000 mg/kg). …”

Shooting an Arrow against Convulsion: Novel Triazole-Grafted Benzenesulfonamide Derivatives as Carbonic Anhydrase II and VII Inhibitors by Mohamed A. Zeidan (21099628)

“…Evaluations of toxicity showed no neurotoxic effects and a high safety margin (LD₅₀ > 2000 mg/kg). …”