Validation of selected genes associated with p53 connection pathway was carried out using quantitative real-time polymerase chain reaction (qRT-PCR) and western immunoblotting. by Mei Yi Sim (4067998)

Tuning Magnetic and Structural Transitions through Valence Electron Concentration in the Giant Magnetocaloric Gd_5–<i>x</i>Eu_<i>x</i>Ge₄ Phases by Jinlei Yao (1712740)

“…A decrease in the valence electron concentration achieved through the substitution of Eu²⁺ for Gd³⁺ leads to the formation of the interslab Ge–Ge dimers, phase transitions to the Gd₅Si₂Ge₂- and Gd₅Si₄-type structures, and a ferromagnetic ordering in the Gd_5–<i>x</i>Eu_<i>x</i>Ge₄ system. …”

Doxycycline modulates VEGF-A expression: Failure of doxycycline-inducible lentivirus shRNA vector to knockdown VEGF-A expression in transgenic mice - Fig 5 by Mari Merentie (4781907)

Box and dot plots show the distribution of TSH concentrations in the different groups. by Martina Schlipf (14498388)

DataSheet1_Zebrafish EEG predicts the efficacy of antiepileptic drugs.pdf by Jun-Nyeong Shin (14234054)

“…We propose a novel method for pharmacological evaluation of AEDs based on EEG from adult zebrafish, which allows researchers to select more clinically valuable drugs at the early stage of AED screening.…”

Potent 5‑Cyano-6-phenyl-pyrimidin-Based Derivatives Targeting DCN1–UBE2M Interaction by Wenjuan Zhou (115285)

“…After finding a novel inhibitor <b>DC-1</b> with IC₅₀ = 1.2 μM, we performed a series of chemical optimizations, which finally led to the discovery of a potent thiazole containing 5-cyano-6-phenylpyrimidin-based inhibitor <b>DC-2</b> (IC₅₀ = 15 nM). …”

Synthesis and Biological Evaluation of New Chalcogen Semicarbazone (<i>S</i>, <i>Se</i>) and Their Azole Derivatives against Chagas Disease by Mercedes Rubio-Hernández (20036142)

“…Seleno-compounds demonstrated enhanced activity and selenazoles showed a decrease in selenium-associated toxicity. Compound 4-methyl-2-(2-(1-(3-nitrophenyl)­ethylidene)­hydrazineyl)-1,3-selenazole (<i><b>Se</b></i><b>2h</b>) emerged as a promising candidate, and its binding to cruzain was investigated. …”

Synthesis and Biological Evaluation of New Chalcogen Semicarbazone (<i>S</i>, <i>Se</i>) and Their Azole Derivatives against Chagas Disease by Mercedes Rubio-Hernández (20036142)

“…Seleno-compounds demonstrated enhanced activity and selenazoles showed a decrease in selenium-associated toxicity. Compound 4-methyl-2-(2-(1-(3-nitrophenyl)­ethylidene)­hydrazineyl)-1,3-selenazole (<i><b>Se</b></i><b>2h</b>) emerged as a promising candidate, and its binding to cruzain was investigated. …”

Design, Synthesis, and Biological Evaluation of Covalent Inhibitors of Focal Adhesion Kinase (FAK) against Human Malignant Glioblastoma by Bo Li (112195)

“…Herein, we report the structure-guided development of a series of covalent inhibitors of FAK. …”

Solvent accessible surface area. by Jingran Wen (4047724)

Solvent-polyQ hydrogen bond count. by Jingran Wen (4047724)

Table_11_Tramadol’s Inhibitory Effects on Sexual Behavior: Pharmacological Studies in Serotonin Transporter Knockout Rats.PDF by Diana C. Esquivel-Franco (5455082)

Exploring the Impacts of Conformer Selection Methods on Ion Mobility Collision Cross Section Predictions by Felicity F. Nielson (10170218)

“…Based on our analyses, we found Boltzmann weighting to be a good trade-off between precision and theoretical accuracy. …”

Solvent-polyQ hydrogen bond count at the atomic level. by Jingran Wen (4047724)

Intra-polyQ hydrogen bonding. by Jingran Wen (4047724)

BRSV RNA detected in nasal swabs of cows that were naturally re-infected four years after a previous natural BRSV infection (n = 7, reinfection) and cows that were naturally infect... by Sara Hägglund (580500)

Data_Sheet_3_Exploring the active ingredients and pharmacological mechanisms of the oral intake formula Huoxiang Suling Shuanghua Decoction on influenza virus type A based on netwo... by Ruying Tang (14036640)

Data_Sheet_14_Exploring the active ingredients and pharmacological mechanisms of the oral intake formula Huoxiang Suling Shuanghua Decoction on influenza virus type A based on netw... by Ruying Tang (14036640)

Data_Sheet_2_Exploring the active ingredients and pharmacological mechanisms of the oral intake formula Huoxiang Suling Shuanghua Decoction on influenza virus type A based on netwo... by Ruying Tang (14036640)

Number of intra-polyQ hydrogen bonds vs. the number of solvent-polyQ hydrogen bond. by Jingran Wen (4047724)