Understanding the Scales Formation Inhibition Mechanism on C-Steel in a Sour Media by Al-Qahtani, Noora

“…In this work, the electrochemical behaviour of C-steel in sour (i) de-ionised water (DIW) and (ii) in different NaCl solutions were examined in an H2S system. A series of experiments were conducted at ambient (RT), 50 oC and at 80 oC using different combinations of inhibitors (A and B). …”
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Increased RhoA activity does not account for the phenotype of double-KD cells. by Laurent Guillemot (284520)

“…<p>(<b>A</b>) RhoA activation assay (GST pulldown assay using the rhotekin-binding-domain, see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0055873#pone.0055873-Guillemot3" target="_blank">[19]</a>), showing that RhoA activity is increased at confluence in double-KD cells, similarly to both CGN and CGNL1 single-KD cells. …”

<i>NDE1</i> plays a critical role in the action of binaphthoquinones. by Ashkan Emadi (248270)

“…Spot assays of wild-type, <i>nde1nde2</i>Δ, <i>nde1</i>Δ, <i>nde2</i>Δ and wild type yeast overexpressing <i>NDE1</i> driven by a GPD promoter (P<i>_GPD</i>-<i>NDE1</i>) were spotted in five fold serial dilutions on plates containing glycerol or glucose and either DMSO or BiQ7, BiQ11 or BiQ3 at their IC₅₀ concentrations. …”

A high content imaging approach was used to identify compounds that cause JLA. by Magdalena L. Circu (846722)

“…The drugs that yield an NPI score of more than 50% and a Z score of less than -4 (right lower quadrant as indicated by the red arrow) were designated as ‘hit’ compounds.…”

<i>Xbp1</i> is a genetic interactor of <i>DmManf</i>. by Riitta Lindström (453311)

“…The amounts of both total and spliced <i>Xbp1</i> transcripts were clearly decreased indicating a successful knockdown of <i>Xbp1</i> gene. …”

The impact of a CTL-based vaccine is dependent upon the extent to which it affects transmission potential. by Helen R. Fryer (194033)

“…Our simulations are based upon an epidemic in a sub-saharan community, thus we assume a basic reproductive number of 2 in the absence of vaccination (,,years⁻¹). …”

Missing puzzle pieces of time-restricted-eating (TRE) as a long-term weight-loss strategy in overweight and obese people? A systematic review and meta-analysis of randomized contro... by Jie-Hua Chen (11471484)

“…Pooled results showed that subjects on TRE regimen (> 4 weeks) achieved a significant weight loss in comparison with unrestricted time regimen (weighted mean difference: −2.32%; 95% CI: −3.50, −1.14%; <i>p</i> < 0.01); however, weight loss was mainly attributed to the loss of lean mass rather than fat mass. …”

Educational outcomes of a new curriculum on interproximal oral prophylaxis for dental students by Denis Bourgeois (225227)

“…At one week, 89.6% of subjects reported using IDBs. Individual use decreased significantly from one week to one month (-26%, p <i>=</i> 0.006) while a non-significant upward trend occurred between one month and three months. …”

Protein-protein docking for Parkin and a charged E2∼Ub complex. by Thomas R. Caulfield (655752)

“…<b>C</b>) Following unbiased MD (>200 ns), the E2-Ub complex moves towards the Parkin's active center. The decreased distance is shown after 50 ns. <b>D</b>) Overall re-orientation of the UBL domain and the E2-Ub complex is shown after 200 ns.…”

RIPK3 enhances innate anti-viral immunity against Influenza A virus. by Jeffrey Downey (3927356)

<i>miR-146a</i> expression in tissue and plasma of OSCC patients. by Pei-Shi Hung (489732)

Bleeding Risk and Mortality of Edoxaban: A Pooled Meta-Analysis of Randomized Controlled Trials by Shuang Li (146392)

Statins and Hip Fracture Prevention – A Population Based Cohort Study in Women by Arja Helin-Salmivaara (123653)

“…When women with poor (<40%), moderate (40 to 80%), and good adherence (≥80%) to statins were compared to those with good adherence to hypertension drugs (≥80%) or to the population cohort, the protective effect associated with statin use attenuated with the decreasing level of adherence.</p> <h3>Conclusions</h3><p>5-year exposure to statins is associated with a reduced risk of low-energy hip fracture in women aged 50–80 years without prior hospitalizations for fractures.…”

Neoadjuvant chemotherapy for muscle invasive bladder cancer: a nationwide investigation on survival by Beth Russell (5095202)

“…This study calculated 5-year survival and risk of bladder cancer (BC)-specific and overall death by Cox proportional hazard models for the study cohort and a propensity score (PS) matched cohort.</p> <p><b>Results:</b> Those who had received NAC had higher 5-year survival proportions and decreased risk of both overall and BC specific death (HR = 0.71, 95% CI = 0.52–0.97 and HR = 0.67, 95% CI = 0.48–0.94), respectively, as compared to patients who did not receive NAC. …”

Antimycin A has broad spectrum antiviral activity against RNA viruses. by Avi Raveh (493231)

“…The calculated IC₅₀ value for antimycin A in the HCV replicon system is shown on the graph. …”

Synthesis and Preclinical Validation of Novel Indole Derivatives as a GPR17 Agonist for Glioblastoma Treatment by Phung Nguyen (230474)

“…The <b>CHBC</b>–GPR17 interaction leads to a rapid decrease of cAMP and Ca²⁺. <b>CHBC</b> exhibits the cytotoxicity effect on GBM cells in a dose-dependent manner with an IC₅₀ of 85 μM, whereas the known agonist MDL29,951 showed a negligible effect. …”

Disease course of Chronic Relapsing Inflammatory Optic Neuropathy (CRION) in a single care center by Luis Enrique MOLINA-CARRIÓN (12687286)

“…Objective: To describe the clinical course during long-term follow-up of patients with a diagnosis of CRION. Methods: From a cohort of 1,735 patients with demyelinating disorders, we selected patients aged over 16 years with CRION according to current criteria. …”

Data_Sheet_1_Effect of a High Fat Diet vs. High Carbohydrate Diets With Different Glycemic Indices on Metabolic Parameters in Male Endurance Athletes: A Pilot Trial.docx by Denise Zdzieblik (12399730)

“…The purpose of this trial was to investigate the effect of a 4-week high fat low carbohydrate (HFLC-G: ≥65% high glycemic carbohydrates per day; n = 9) vs. high carbohydrate low glycemic (LGI-G: ≥65% low glycemic carbohydrates daily; n = 10) or high glycemic (HGI-G: ≥65% fat, ≤ 50 g carbohydrates daily; n = 9) diet on fat and carbohydrate metabolism at rest and during exercise in 28 male athletes. …”

Measuring and Reducing Chemical Spills by Students: A Randomized Controlled Trial of Providing Feedback by Aimilia M. Tsokou (7272506)

“…A Hodges–Lehmann estimator for the median change in volume spilled during the second experiment due to providing feedback on spillage during first experiment was a 50% decrease in volume spilled (95% confidence range: 0 to 80% decrease, Mann–Whitney <i>U</i> test <i>p</i> = 0.05). …”

A prospective study of the influence of the skeleton on calcium mass transfer during hemodialysis by Patricia Taschner Goldenstein (5570870)

“…</p><p>Results</p><p>Calcium mass transfer varied widely among patients in each study phase with a median of -89.5, -76.8 and -3 mmol using d[Ca] 1.25 mmol/L, -106, -26.8 and 29.7 mmol using d[Ca] 1.50 mmol/L, and 12.8, -14.5 and 38 mmol using d[Ca] 1.75 mmol/L during pre-PTX, early post-PTX and late post-PTX, respectively, which was significantly different among d[Ca] (p = 0.0001) and among phases (p = 0.040). …”