TLR3 deficiency promoted the activation of TGF-β1/Smad2/3 pathway and myofibroblast caused by <i>C</i>. by Yuru Wang (846969)

<i>C. sinensis</i> ESPs facilitated ferroptosis in AML12 cells. by Haoyang Zhang (1706815)

Supplementary Material for: Should Colorectal Cancer Screening in Portugal Start at the Age of 45 Years? A Cost-Utility Analysis by Currais P. (10117210)

“…<b><i>Results:</i></b> In Portugal, in 1993–2010, there was an increase in CRC incidence of 17% (from 25 to 30/100,000), 35% (from 39 to 54/100,000), and 71% (from 52 to 97/100,000) in patients aged 45–49 years, 50–54 years, and 55–59 years, respectively. The mortality rate of patients aged 45–54 years remained stable between 2003 and 2016 (12/100,000) as a counterpoint to a moderate decrease in those aged 55–64 years (from 38 to 35/100,000) and a sharp reduction in those aged 65–75 years (from 93 to 75/100,000). …”

Image_1_Hsa_circ_0000479 as a Novel Diagnostic Biomarker of Systemic Lupus Erythematosus.TIF by Gangqiang Guo (3278922)

“…Western blotting revealed that the expression of Wnt-16 protein was significantly decreased in SLE.</p><p>Conclusion: Our results suggest that hsa_circ_0000479 has potential as a novel biomarker for the diagnosis of SLE.…”

Image_2_Hsa_circ_0000479 as a Novel Diagnostic Biomarker of Systemic Lupus Erythematosus.TIF by Gangqiang Guo (3278922)

“…Western blotting revealed that the expression of Wnt-16 protein was significantly decreased in SLE.</p><p>Conclusion: Our results suggest that hsa_circ_0000479 has potential as a novel biomarker for the diagnosis of SLE.…”

S1 Graphical abstract - by Lefei Yu (12274846)

“…<div><p>A number of studies demonstrate the therapeutic effectiveness of <i>Radix Bupleuri</i> (RB) and <i>Hedysarum Multijugum Maxim</i> (HMM) in treating liver fibrosis, but the exact molecular mechanisms remain unclear. …”

The top 10 hub targets. by Lefei Yu (12274846)

“…<div><p>A number of studies demonstrate the therapeutic effectiveness of <i>Radix Bupleuri</i> (RB) and <i>Hedysarum Multijugum Maxim</i> (HMM) in treating liver fibrosis, but the exact molecular mechanisms remain unclear. …”

Original images for blots and gels requirements. by Lefei Yu (12274846)

“…<div><p>A number of studies demonstrate the therapeutic effectiveness of <i>Radix Bupleuri</i> (RB) and <i>Hedysarum Multijugum Maxim</i> (HMM) in treating liver fibrosis, but the exact molecular mechanisms remain unclear. …”

The top 10 active ingredients. by Lefei Yu (12274846)

“…<div><p>A number of studies demonstrate the therapeutic effectiveness of <i>Radix Bupleuri</i> (RB) and <i>Hedysarum Multijugum Maxim</i> (HMM) in treating liver fibrosis, but the exact molecular mechanisms remain unclear. …”

PEG10-derived VLPs are naturally released by human cells. by Will Campodonico (20485651)

The flow chart. by Lefei Yu (12274846)

“…<div><p>A number of studies demonstrate the therapeutic effectiveness of <i>Radix Bupleuri</i> (RB) and <i>Hedysarum Multijugum Maxim</i> (HMM) in treating liver fibrosis, but the exact molecular mechanisms remain unclear. …”

The active ingredients in RB-HMM. by Lefei Yu (12274846)

“…<div><p>A number of studies demonstrate the therapeutic effectiveness of <i>Radix Bupleuri</i> (RB) and <i>Hedysarum Multijugum Maxim</i> (HMM) in treating liver fibrosis, but the exact molecular mechanisms remain unclear. …”

Brg1 inhibition reduces KSHV lytic reactivation. by Praneet Kaur Sandhu (21156149)

Poly (I:C) intervention presented significantly beneficial on the liver lesion, liver inflammation and biliary injury caused by <i>C</i>. by Yuru Wang (846969)

Early mobilization of critically ill patients in the intensive care unit: A systematic review and meta-analysis by Lan Zhang (90951)

“…</p><p>Conclusions</p><p>Early mobilization appears to decrease the incidence of ICU-AW, improve the functional capacity, and increase the number of ventilator-free days and the discharged-to-home rate for patients with a critical illness in the ICU setting.…”

Linaclotide in Chronic Idiopathic Constipation Patients with Moderate to Severe Abdominal Bloating: A Randomized, Controlled Trial by Brian E. Lacy (776932)

“…Approximately one-third of linaclotide patients (each group) had ≥50% mean decrease from baseline in abdominal bloating vs. 18% of placebo patients (<i>P</i><0.01). …”

The METTL3 phosphorylation sites targeted by ERK2 are essential for PRV replication. by Lucai Wang (22050158)

Table_1_Case Report: A Novel Mutation in NFKB1 Associated With Pyoderma Gangrenosum.DOCX by Ran Fang (533948)

“…The functional analysis showed that the variant caused reduced phosphorylation of p105 and resulted in the decreased processing of p105 to p50. We conclude that the patient's symptoms were caused by dysregulation of the NF-κB signaling pathway.…”

Table_2_Case Report: A Novel Mutation in NFKB1 Associated With Pyoderma Gangrenosum.DOCX by Ran Fang (533948)

“…The functional analysis showed that the variant caused reduced phosphorylation of p105 and resulted in the decreased processing of p105 to p50. We conclude that the patient's symptoms were caused by dysregulation of the NF-κB signaling pathway.…”

AZ10606120 treatment significantly increased cytotoxicity and reduced cell number in a dose-dependent manner. by Matthew Drill (22258391)

“…Cell numbers were significantly decreased in cells after treatment with AZ10606120 (50µM) compared to both temozolomide (TMZ; 50µM) treatment and untreated controls. …”