Linaclotide in Chronic Idiopathic Constipation Patients with Moderate to Severe Abdominal Bloating: A Randomized, Controlled Trial by Brian E. Lacy (776932)

“…Approximately one-third of linaclotide patients (each group) had ≥50% mean decrease from baseline in abdominal bloating vs. 18% of placebo patients (<i>P</i><0.01). …”

Brg1 inhibition reduces KSHV lytic reactivation. by Praneet Kaur Sandhu (21156149)

Table_1_Case Report: A Novel Mutation in NFKB1 Associated With Pyoderma Gangrenosum.DOCX by Ran Fang (533948)

“…The functional analysis showed that the variant caused reduced phosphorylation of p105 and resulted in the decreased processing of p105 to p50. We conclude that the patient's symptoms were caused by dysregulation of the NF-κB signaling pathway.…”

Table_2_Case Report: A Novel Mutation in NFKB1 Associated With Pyoderma Gangrenosum.DOCX by Ran Fang (533948)

“…The functional analysis showed that the variant caused reduced phosphorylation of p105 and resulted in the decreased processing of p105 to p50. We conclude that the patient's symptoms were caused by dysregulation of the NF-κB signaling pathway.…”

Poly (I:C) intervention presented significantly beneficial on the liver lesion, liver inflammation and biliary injury caused by <i>C</i>. by Yuru Wang (846969)

AZ10606120 treatment significantly increased cytotoxicity and reduced cell number in a dose-dependent manner. by Matthew Drill (22258391)

“…Cell numbers were significantly decreased in cells after treatment with AZ10606120 (50µM) compared to both temozolomide (TMZ; 50µM) treatment and untreated controls. …”

Recognition of Double Strand Breaks by a Mutator Protein (MU2) in <em>Drosophila melanogaster</em> by Raghuvar Dronamraju (204100)

“…Studies pertaining to the generation, maintenance, and biological effects of telomere formation are limited in metazoans. A mutation, <em>mu2^a</em>, in <em>Drosophila melanogaster</em> decreases the rate of repair of double strand DNA breaks in oocytes, thus leading to chromosomes that have lost a natural telomere and gained a new telomere. …”

The METTL3 phosphorylation sites targeted by ERK2 are essential for PRV replication. by Lucai Wang (22050158)

Disruption of <i>shk-1</i> increases susceptibility to bacterial pathogens. by Longjun Pu (20685717)

TLR3 deficiency exacerbated liver inflammation and biliary damage caused by <i>C</i>. by Yuru Wang (846969)

Average distance of agents to the goal with signaling (top) and a control run with signaling switched off (bottom). by Olaf Witkowski (2633398)

table1_Species Quantification in Complex Herbal Formulas—Vector Control Quantitative Analysis as a New Method.doc by Bo Zhao (13553)

image1_Species Quantification in Complex Herbal Formulas—Vector Control Quantitative Analysis as a New Method.jpeg by Bo Zhao (13553)

Data_Sheet_1_Altered zinc homeostasis in a primary cell culture model of the retinal pigment epithelium.DOCX by Ana Álvarez-Barrios (15301603)

“…Zn cytoplasmic concentrations significantly decreased 0.2 times at 59 days, from 0.264 ± 0.119 ng·μg⁻¹ at 10 days to 0.062 ± 0.043 ng·μg⁻¹ at 59 days (p < 0.05). …”

Table_1_Central Multifocal Choroiditis: Platelet Granularity as a Potential Marker for Treatment With Steroid-Sparing Immunomodulatory Therapy.docx by Evianne L. de Groot (11937257)

Diversity and Composition of Demersal Fishes along a Depth Gradient Assessed by Baited Remote Underwater Stereo-Video by Vincent Zintzen (129134)

“…Species richness peaked in shallow depths, followed by a decrease beyond 100 m to a stable average value from 700 to 1200 m. …”

Rational Design of Suprastat: A Novel Selective Histone Deacetylase 6 Inhibitor with the Ability to Potentiate Immunotherapy in Melanoma Models by Satish Noonepalle (7344425)

Table_1_Intestinal metabolites and the risk of autistic spectrum disorder: A two-sample Mendelian randomization study.xls by Deyang Liu (12256569)

Tailored dose baclofen in patients with alcoholic liver disease: A case series with 2-year follow-up of hospitalisation by Mathis Heydtmann (820078)

STM2457 and PD98059 enhanced PRV replication <i>in vivo.</i> by Lucai Wang (22050158)