IRF7 expression modulates HIV-1 replication in primary macrophages. by Mélissa Sirois (195202)

“…<p>A) Level of <i>IRF7</i> gene expression in macrophages treated with siRNA targeting <i>IRF7</i> (50 nM) [n = 3] compared to a control non-targeted siRNA [n = 3] resulted in a 55% reduction in <i>IRF7</i> gene expression. …”

Bifurcated Halogen Bonding Involving Diaryliodonium Cations as Iodine(III)-Based Double-σ-Hole Donors by Irina S. Aliyarova (9981605)

“…An XB with the iodine­(III) center of a diaryliodonium cation can be formed even when ∠(C–I···X) is much less than 180° (decrease by 55° in our experiments). …”

Age-Associated Lipidome Changes in Metaphase II Mouse Oocytes by Hyuck Jun Mok (600066)

“…To investigate if aged oocytes display an altered lipidome compared to young oocytes, we performed a global lipidomic analysis between oocytes from 4-week-old and 42 to 50-week-old mice. …”

Image_1_Loss of DEK Expression Induces Alzheimer’s Disease Phenotypes in Differentiated SH-SY5Y Cells.TIF by Allie N. Greene (9644915)

Influence of Gravity on the Sliding Angle of Water Drops on Nanopillared Superhydrophobic Surfaces by Hao Li (31608)

File contains the zipped set of figures for this paper in PNG format. by Piotr Borkowski (15195012)

“…S4_14_Fig.png: Effects of similarity perturbation within a class of data. Upper line represents the maximal quotient and the lower line represents the minimal quotient of eigenvalues after and before perturbing the similarity matrix, as described in the text, depending on the maximal similarity decrease factor. …”

Concordant and discordant read coverage reveal extensive similarity between the tumor and control. by Cem Sievers (584576)

“…In contrast, heterozygous events contain both a wildtype allele and an acquired SV, and are therefore characterized by a decrease within the concordant coverage to 50% (III). …”

Electrophysiological response of Be2C cells in response to stimulation with morphine. by Marino Convertino (247429)

“…<b>B)</b> Morphine stimulation of Be2C cells transfected with the 6TM-mOR leads to a decrease in an outward current with a reversal potential near -80 mV, suggesting that K⁺ conductance is reduced. …”

CPF alone prevented ability of adipogenic cocktail (DMI) towards differentiation of C₃H₁₀T½ cells to adipocytic lineage. by Harkirat Singh Sandhu (3836335)

“…Increasing concentrations of CPF (0.01, 0.1, 1, 10, 25, 50 and 100 μM) caused a gradual decrease in lipid vesicle accumulation of DMI-treated cells (e-k). …”

Double immunohistostaining of alpha-synuclein and TH. by Nian Xiong (218611)

“…The last graph of the three rows was obtained by the overlapping the first three graphs (Scale bars = 50 µm). Compared with the contralateral side of the ST models (A-D), a dose-dependent increase in alpha-synuclein expression in the lesioned brain and a decrease in the number of TH-positive neurons are shown in E–H (3-µg group) and I–L (12-µg group). …”

The proportion of homomeric GluR1 AMPA receptors in the post-synaptic sites is not altered following LTP induction. by Agnès Villers (316323)

“…<p>In these experiments, slices were treated with a 1-hour perfusion of NASPM (50 µM), an inhibitor of GluR2-lacking AMPA receptors. …”

Efflux of ethidium bromide. by Helen E. McNeil (8190873)

“…Data presented is the time taken for the fluorescence to decrease by 25% +/- SE. (Data for 10% and 50% drop can be seen in <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1008101#ppat.1008101.s011" target="_blank">S1 Table</a>). …”

Clomiphene citrate effect in obese men with low serum testosterone treated with metformin due to dysmetabolic disorders: A randomized, double-blind, placebo-controlled study by Carla Pelusi (4422919)

“…Compared to baseline levels, T levels increased significantly after 3 months of CC treatment (3.03±0.80 to 5.99±1.67 ng/mL P<0.001) but not after the Plac treatment (2.87±0.78 to 3.09±0.84 ng/mL P<0.001 between the treatments). …”

Supplementary Material for: Impact of Simulated Hyperventilation and Periodic Breathing on Sympatho-Vagal Balance and Hemodynamics in Patients with and without Heart Failure by Spiesshoefer J. (7139138)

“…<b><i>Results:</i></b> In healthy subjects, voluntary hyperventilation led to a 50% decrease in the mean BRS slope and a 29% increase in CI compared to baseline values (<i>p</i> < 0.01 and <i>p</i> < 0.05). …”

(a) Western blot of MDA-MB 435 breast cancer cells cultured on fibronectin for 1 hour by Robert F. Klees (62686)

“…Positive control (lane 1) and ethanol control (lane 2) were compared to cells treated with 36 ng/μl of either compound A5, A8, 5, or 9 (lanes 3, 4, 5, and 6, resp) by probing with a monoclonal antibody for Cdc42. …”

Cell death and JNK activation in SH-SY5Y cells stimulated with H₂O₂ overnight or for 3 h. by Marco Feligioni (287395)

“…<b>D</b>) Cell viability assay was performed employing MTT colorimetric method. A concentration dependent decrease in cell viability is observed following 3 h stimulation with H₂O₂ (50 mM: ∼30%; 75 mM: ∼50%). …”

Astrocytic volume changes in the cortex of GFAP/EGFP and GFAP/EGFP/α-Syn^−/− mice during hyperosmotic stress. by Miroslava Anderova (155561)

Hit expansion around chloroxine. by Sam Barker (4832121)

“…This modification causes a significant decrease in this compound’s activity as a co-treatment with ceftazidime, with a <i>p</i>IC50 ≈ 3.4. 5,7-dichloro-2-methyl-8-quinolinol differs from chloroxine by addition of a methyl group in the 2-position (B). …”

Effect of BC-819 on cell growth in different lung cancer cell lines. by Günther Hasenpusch (350166)

“…The influence of BC-819 on bioluminescent A549-C8-luc was examined as well and revealed decreased luciferase and therefore reduced cell growth (more than 50%) as early as after 24 hours (C). …”

Dissociation, and not specific actions of Trypsin-EDTA, acts to suppress neurectoderm formation. by James N. Hughes (319868)

“…Error bars represent sem. (a) denotes a decrease compared to MEDII⁻/Dissociation⁻ where p<0.01. …”