Table_2_The Impact of the COVID-19 Pandemic on Women’s Reproductive Health.docx by Niamh Phelan (10450682)

“…</p>Results<p>1031 women completed the survey. Mean age was 36.7 ± 6.6 years (range, 15–54). 693/70% reported recording their cycles using an app or diary. 233/23% were using hormonal contraception. 441/46% reported a change in their menstrual cycle since the beginning of the pandemic. 483/53% reported worsening premenstrual symptoms, 100/18% reported new menorrhagia (p = 0.003) and 173/30% new dysmenorrhea (p < 0.0001) compared to before the pandemic. 72/9% reported missed periods who not previously missed periods (p = 0.003) and the median number of missed periods was 2 (1–3). 17/21% of those who “occasionally” missed periods pre-pandemic missed periods “often” during pandemic. 467/45% reported a reduced libido. …”

Table_2_The Impact of the COVID-19 Pandemic on Women’s Reproductive Health.docx by Phelan Niamh (10342460)

“…</p>Results<p>1031 women completed the survey. Mean age was 36.7 ± 6.6 years (range, 15–54). 693/70% reported recording their cycles using an app or diary. 233/23% were using hormonal contraception. 441/46% reported a change in their menstrual cycle since the beginning of the pandemic. 483/53% reported worsening premenstrual symptoms, 100/18% reported new menorrhagia (p = 0.003) and 173/30% new dysmenorrhea (p < 0.0001) compared to before the pandemic. 72/9% reported missed periods who not previously missed periods (p = 0.003) and the median number of missed periods was 2 (1–3). 17/21% of those who “occasionally” missed periods pre-pandemic missed periods “often” during pandemic. 467/45% reported a reduced libido. …”

Table_1_The Impact of the COVID-19 Pandemic on Women’s Reproductive Health.docx by Niamh Phelan (10450682)

“…</p>Results<p>1031 women completed the survey. Mean age was 36.7 ± 6.6 years (range, 15–54). 693/70% reported recording their cycles using an app or diary. 233/23% were using hormonal contraception. 441/46% reported a change in their menstrual cycle since the beginning of the pandemic. 483/53% reported worsening premenstrual symptoms, 100/18% reported new menorrhagia (p = 0.003) and 173/30% new dysmenorrhea (p < 0.0001) compared to before the pandemic. 72/9% reported missed periods who not previously missed periods (p = 0.003) and the median number of missed periods was 2 (1–3). 17/21% of those who “occasionally” missed periods pre-pandemic missed periods “often” during pandemic. 467/45% reported a reduced libido. …”

Image_1_Different Renal Function Patterns in Patients With Acute Heart Failure: Relationship With Outcome and Congestion.jpeg by Alberto Palazzuoli (12203753)

“…</p>Results<p>We recruited 467 subjects with a mean congestion score of 3.5±1.08 and a median creatinine value of 1.28 (1.00–1.70) mg/dl, eGFR 50 (37–65) ml/min/m² and NTpro B-type natriuretic peptide (BNP) 7,000 (4,200–11,700) pg/ml. …”

Table_1_The Impact of the COVID-19 Pandemic on Women’s Reproductive Health.docx by Phelan Niamh (10342460)

“…</p>Results<p>1031 women completed the survey. Mean age was 36.7 ± 6.6 years (range, 15–54). 693/70% reported recording their cycles using an app or diary. 233/23% were using hormonal contraception. 441/46% reported a change in their menstrual cycle since the beginning of the pandemic. 483/53% reported worsening premenstrual symptoms, 100/18% reported new menorrhagia (p = 0.003) and 173/30% new dysmenorrhea (p < 0.0001) compared to before the pandemic. 72/9% reported missed periods who not previously missed periods (p = 0.003) and the median number of missed periods was 2 (1–3). 17/21% of those who “occasionally” missed periods pre-pandemic missed periods “often” during pandemic. 467/45% reported a reduced libido. …”

Image_2_Different Renal Function Patterns in Patients With Acute Heart Failure: Relationship With Outcome and Congestion.jpeg by Alberto Palazzuoli (12203753)

“…</p>Results<p>We recruited 467 subjects with a mean congestion score of 3.5±1.08 and a median creatinine value of 1.28 (1.00–1.70) mg/dl, eGFR 50 (37–65) ml/min/m² and NTpro B-type natriuretic peptide (BNP) 7,000 (4,200–11,700) pg/ml. …”

Effect of OWB extract and CA on pro-inflammatory and anti-inflammatory cytokine release in LPS-induced peritoneal macrophages by sandwich ELISA and RT-PCR. by Durbadal Ojha (475076)

“…<p>Peritoneal macrophages were cultured overnight and incubated with LPS (1 µg/ml), washed after 4 h and then treated with the OWB (50 or 100 µg/m) or CA (10 µg/ml). The cells were further incubated for 24 h, and the cell-free supernatants were subjected to sandwich ELISA to determine the level of (A) TNF-α, (C) IL-1β, (E) IL-6 and (G) IL-6 (pg/mL). …”

TbCDC34 activity is modulated by compound CC0651. by Federico Rojas (480253)

“…Samples treated with CC0651 showed a decrease of cells with 1N1K and an increase of cells with 2N2K. …”

Effect of IL-17A, IL-17F or IL-22 on TER of cultured ARPE-19 monolayer. by Ying Chen (9697)

“…Incubation of ARPE-19 monolayers with 50 ng/ml IL-17A or IL-17F induced a gradual decrease of TER, and a significant effect occurred 5 days (p = 0.019, p = 0.045) after stimulation. …”

Effects of (a) AG-490 and (b) WHI-P154 on IFN-γ-induced nitric oxide (NO) generation in J774 macrophages by Outi Sareila (66176)

“…</p><p></p> After 24-hour incubation with IFN-γ (5 ng/mL), the supernatants were collected and nitrite was measured in the culture medium as an indicator of NO production by Griess reaction. …”

IL-1β treatment does not induce cell death. by Himakarnika Alluri (2735689)

“…<p>IL-1β (10 ng/mL; 2 hours) treatment had no effect on cell viability (n = 5). …”

(S)-2 induced apoptosis in LNCaP cells. by Anna Laurenzana (296271)

“…Mitochondrial depolarization is indicated by a decrease in the red/green (R/G) fluorescence intensity ratio <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0058267#pone.0058267-Salvioli1" target="_blank">[32]</a>. …”

HO-1 deficiency leads to poor bacterial clearance <i>in vivo</i> and <i>in vitro</i>. by Satindra Gahlot (3615662)

“…Data are means ±SD of 3 independent experiments. Statistical significance *p<0.001 a significant decrease compared to MRSA alone exposed cultures; and #p<0.001 a significant increase compared to MRSA +CoPP treated cultures. …”

Supplementary Material for: Nomograms of Fetal Right Ventricular Fractional Area Change by 2D Echocardiography by Guirado L. (6174176)

“…In contrast, RV FAC showed a slight quadratic decrease throughout gestation (mean RV FAC ranged from 36% at 18 weeks of gestation [10–90th centiles: 25–47%, respectively] to 29% at 41 weeks [10–90th centiles: 18–40%, respectively]). …”

The <i>casy-1</i> isoforms functions in GABAergic neurons to regulate synaptic transmission. by Shruti Thapliyal (4951993)

“…Cholinergic synapses are largely normal in <i>casy-1</i> mutants, while GABAergic synapses showed a subtle but significant decrease in fluorescent intensity when compared to WT animals. …”

Syntheses, Crystal Structures, and Physical Properties of La₅Cu₆O₄S₇ and La₅Cu_6.33O₄S₇ by George H. Chan (2419864)

“…In going from La₅Cu₆O₄S₇ to La₅Cu_6.33O₄S₇, the disruption of the ²_∞[Cu₆S₆⁵⁻] layer and the decrease in the overall Cu²⁺ (3d⁹) concentration lead to a significant decrease in the electrical conductivity.…”

Syntheses, Crystal Structures, and Physical Properties of La₅Cu₆O₄S₇ and La₅Cu_6.33O₄S₇ by George H. Chan (2419864)

“…In going from La₅Cu₆O₄S₇ to La₅Cu_6.33O₄S₇, the disruption of the ²_∞[Cu₆S₆⁵⁻] layer and the decrease in the overall Cu²⁺ (3d⁹) concentration lead to a significant decrease in the electrical conductivity.…”

UTX-1 is required for VPA action in <i>C. elegans</i> embryos and in human cells. by Rakel Brendsdal Forthun (121022)

“…Numbers shown are arbitrary units compared to negative control siRNA. The blot shows a 60% decrease in UTX by siRNA treatment, confirming the efficacy of transfection. …”

EGFR inhibitor differentially modulates the expression of antigen presenting molecules and PD-L1 on HaCaT cells. by Jin S. Im (234975)

“…(B) HaCaT cells were treated with IFNγ at different concentrations ranging 1 pg/ml to 1000 pg/ml in the presence or absence of erlotinib at concentration of 10 μM for 24 hours, and assessed for surface expression of MHC-I, MHC-II, and PD-L1 in Mean Fluorescence Intensity (MFI). While the expression of MHC-I and MHC-II on HaCaT cells was further up-regulated in the presence of erlotinib and IFNγ at all dose range tested for MHC-I and at a greater than 1pg/ml for MHC-II compared to IFNγ alone, IFNγ induced overexpression of PD-L1 was abrogated by the addition of erlotinib to IFNγ at a greater than 100 pg/ml. …”

BPLF1 deubiquitinates TOP2 and stabilizes TOP2ccs. by Jinlin Li (2267896)

“…Clearance was calculated as 1- (intensity of the smears after treatment for 4 h/intensity of the smears after treatment for 30 min) x100. Treatment with MG132 reduced the clearance of TOP2ccs in BPLF1 negative cells and a similar reduction was achieved by expression of BPLF1 in Dox treated cells. …”