Data_Sheet_1_Quantitation of a Novel Engineered Anti-infective Host Defense Peptide, ARV-1502: Pharmacokinetic Study of Different Doses in Rats and Dogs.pdf by Alexandra Brakel (7858097)

“…The plasma concentrations peaked at 15 min post-injection at 1 μg/mL (dogs) and 12 μg/mL (rats) and decreased exponentially within 3 h to 4 and 16 ng/mL, respectively. …”

Rv1460 represses its own expression. by Danicke Willemse (5488697)

“…<i>smegmatis</i> with a protein expression vector either encoding no protein (pSE100) or encoding Rv1460 (indicated by the grey oval). …”

OSM activates ERK-1/2, SAPK/JNK-1/2 MAP kinases, the PI3-kinase Akt and STAT1/3 in HCT116 cells and STAT3 activation is dependent of the LIFR. by Florian Beigel (174724)

“…<p>(A) Stimulation with OSM (100 ng/mL) resulted in increased phosphorylation of ERK-1/2, SAPK/JNK-1/2 kinases and induced PI3 kinase-dependent Akt phosphorylation. …”

Effect of heparanase on activation of T lymphocytes. by Menachem Bitan (365486)

“…Addition of heparanase to the culture medium resulted in a significant (p<0.01) dose dependent decrease in ConA activation and proliferation of the spleen cells. …”

Table 1_The impact of percutaneous endoscopic gastrostomy on nutritional status and survival in cervical esophageal cancer patients undergoing chemoradiotherapy.docx by Zijun Wen (21596450)

“…The 2, 3, and 4 year OS rates for the PEG group were 81.9% (95% confidence interval [CI]: 63.2–100%), 54.3% (95% CI: 25.5–83.1%), and 32.6% (95% CI: 0.0–63.6%), respectively, while the Non-PEG group had 2, 3, and 4 year OS rates of 100% (95% CI: 83.0–100%), 82.1% (95% CI: 59.2–100%), and 49.2% (95% CI: 11.4–87.0%), respectively. …”

Data_Sheet_1_Trends in mortality and causes of death among Chinese adolescents aged 10–19 years from 1990 to 2019.ZIP by Jiaxin Zhu (446571)

“…Regarding age, compared with those aged 10–14 years, the mortality rate of adolescents aged 15–19 years had a higher mortality (35.9/100,000 vs. 21.2 in 2019) and a slower decrease rate (percent: −57.6 vs. −63.2). …”

R154Q mutation lowers membrane association density. by Tingting Wu (228837)

“…<p>Protein adsorption isotherm on GUVs composed of A) 100% DOPS and B) 60% DOPC, 20% DOPS, 10% DOPE, and 10% PI(4,5)P₂. …”

Peregrine falcon egg pollutants by Simon Schwarz (842588)

“…The DDT metabolite, dichlorodiphenyldichloroethene (DDE) (11,800 ng/g dry matter), was found to be the most highly concentrated egg contaminant followed by 2,2′,4,4′,5,5′-hexachlorobiphenyl (3800 ng/g). …”

Reactions of NPY+ and ChAT+ interneurons to QA. by Qiqi Feng (535984)

“…Cont is short for control. Scale bars: A–D, 100 μm; A′–D′, 30 μm; B*, 10 μm.</p>…”

Oligodendrocyte ablation modifies the expression of axonal guidance molecules and neuronal plasticity markers. by Sandrine Doretto (221560)

“…Scale bar 100 µm. Quantification (expressed as % of control) of Netrin-1 shows a decrease of its expression in granule cell precursors of the external granular layer; while a concomitant increase of Sema3A expressed by Purkinje neurons is observed in MBP-TK mice versus WT siblings. …”

Changes in the Bacterial Community Structure of Remediated Anthracene-Contaminated Soils by Laura Delgado-Balbuena (3211080)

“…On the one hand, application of earthworms removed most of the contaminant from the arable soil and had a strong effect on the bacterial community structure, i.e. a decrease in the relative abundance of the Acidobacteria, Chloroflexi and Gemmatimonadetes, and an increase in that of the Proteobacteria compared to the unamended soil. …”

<i>In vivo</i> analysis of the P1' Specificity of the pTEV2 protease. by Christian Renicke (585725)

“…<b>B</b>) Quantification of the P1' Specificity of the pTEV2 protease. Decrease of full length tester construct after two hours was normalized to initial values and relative efficiency normalized to proline was calculated (cleavage efficiency = ([X]_2h/[Pro]_2h×100-100) ×(−1)), assuming that the recognition sequence with proline at the P1’ Position is not cleaved at all. …”

<i>Sox10</i>-GFP^neg OPCs do not rescue the myelination phenotype in adult mice. by Shayan Moghimyfiroozabad (19066182)

“…<p>(A) Low magnification of a coronal brain section of adult mouse immunostained for myelin basic protein (MBP, magenta) and 2′,3′-Cyclic nucleotide 3′-phosphodiesterase (CNP, red) illustrates the almost total absence of myelination in the dorsal forebrain upon genetic ablation of <i>C1ql1</i>-expressing OPCs (upper panel). …”

Single stranded DNA extension analysis of MutL binding activity. by Jonghyun Park (237480)

“…<p>(<b>A</b>) A 5.3 kb ssDNA is coiled randomly at a stretching force of 2.5 pN. …”

Cell wall damage followed by remodeling occurs during adaptation to 5-flucytosine stress. by Catarina Costa (322963)

“…<p>A) <i>C</i>. <i>glabrata</i> KUE100 cells exposed to lyticase stress were harvested in the exponential phase of growth in the absence of stress (♦) or upon 30 min of exposure to 0.7 mg/L 5-flucytosine (■), or in the exponential phase of growth reached upon adaptation to 0.7 mg/L 5-flucytosine (▲). …”

Trends in prostate cancer mortality in the state of São Paulo, 2000 to 2015 by Carolina Terra de Moraes Luizaga (10434025)

“…RESULTS For the state of São Paulo, age-adjusted mortality rates were 15.2, 13.3 and 11.9 per 100,000 men, respectively, in the periods between 2000 to 2005, 2006 to 2010 and 2011 to 2015, with a significant decrease trend (AAPC = -2.10%; 95%CI -2.42 – -1.79) each year. …”

Supplementary Material for: Identification of Candidate Genes and Pathways in Nonsegmental Vitiligo Using Integrated Bioinformatics Methods by Liu B. (3923441)

“…<i>PPARG</i>, <i>MUC1</i>, <i>S100A8</i>, and <i>S100A9</i> were identified as key hub genes involved in the pathogenesis of vitiligo. …”

Histological evaluation of infected pressure ulcers in diabetic TALLYHO/JngJ mice. by Haroon Mohammad (757134)

“…(d) On closer view, bacteria are less numerous and form small clusters compared to negative controls and collagen fibers are visible (dashed box). Scale bar represents 100 μm. (e) Ebselen-treated animals had a pronounced decrease in bacterial burden compared to the negative control, with few scattered aggregates in the deep dermis (arrows) and normal collagen fiber architecture in between. …”

POTASSIUM DOES NOT ATTENUATE SALT STRESS IN YELLOW PASSION FRUIT UNDER IRRIGATION MANAGEMENT STRATEGIES by GEOVANI SOARES DE LIMA (5084936)

“…The experiment was conducted under field conditions in São Domingos, PB, Brazil. A randomized block design was used in a 6 * 2 factorial scheme. …”

TEA block of transient K current in rabbit CB chemoreceptor cells by Olaia Colinas (45959)

“…(A) Representative experiment showing the decrease in the peak current amplitude in depolarizing pulses to +40 mV upon application to the bath solution of TEA at concentrations from 10 M to 10 M as indicated. …”