Effect of control or Notch3 ASOs on <i>Notch3</i> mRNA expression and cell replication in calvarial osteoblast-enriched cells. by Ernesto Canalis (516050)

Representative experimental samples. by Weisheng Zhao (3746023)

“…Based on the mechanical test results, reducing humidity can decrease the loss of uniaxial compressive strength (UCS) caused by moisture absorption from approximately 50% to 15.48%. …”

Mechanical testing apparatus and samples. by Weisheng Zhao (3746023)

“…Based on the mechanical test results, reducing humidity can decrease the loss of uniaxial compressive strength (UCS) caused by moisture absorption from approximately 50% to 15.48%. …”

Relationship between UCS, E, and water content. by Weisheng Zhao (3746023)

“…Based on the mechanical test results, reducing humidity can decrease the loss of uniaxial compressive strength (UCS) caused by moisture absorption from approximately 50% to 15.48%. …”

Hygroscopic experimental device. by Weisheng Zhao (3746023)

“…Based on the mechanical test results, reducing humidity can decrease the loss of uniaxial compressive strength (UCS) caused by moisture absorption from approximately 50% to 15.48%. …”

The mean relative error and standard deviation (vertical bar) versus the number of receive channels for acceleration factors of 2 and 3, showing that the error increases as the num... by Kamlesh Pawar (425523)

Thymidine phosphorylase and prostrate cancer cell proliferation inhibitory activities of synthetic 4-hydroxybenzohydrazides: <i>In vitro</i>, kinetic, and <i>in silico</i> studies... by Sumaira Javaid (7886897)

Variations in the prevalence of episiotomy in France between 2010 and 2021 according to the classification for episiotomy practices. by Raphaele Houlbracq (20558509)

Placenta-Enriched LincRNAs <i>MIR503HG</i> and <i>LINC00629</i> Decrease Migration and Invasion Potential of JEG-3 Cell Line by Bruna Rodrigues Muys (2588305)

“…Further analysis, using a cancer cell lines panel, showed that <i>MIR503HG and LINC00629</i> were expressed in 50% and 100% of the cancer cell lines, respectively. …”

Depletion of CD25⁺ cells decreased the percentage of IL-17 and IFN-γ CD4⁺ Th cells in the LRN of infected mice. by Adam N. Odeh (3170022)

HbA1c, BMI and Lipid levels of study participants (n = 382). by Habiba I. Ali (10451382)

PGRP-LC in the gut promotes ageing by <i>A</i>. <i>persici</i>. by Taro Onuma (15195377)

Addressing a Trapped High-Energy Water: Design and Synthesis of Highly Potent Pyrimidoindole-Based Glycogen Synthase Kinase-3β Inhibitors by Stanislav Andreev (11067165)

“…Surprisingly, our results demonstrate that this high-energy water was not displaced by our potent inhibitor (<i>S</i>)-3-(3-((7-ethynyl-9<i>H</i>-pyrimido­[4,5-<i>b</i>]­indol-4-yl)­(methyl)­amino)­piperidin-1-yl)­propanenitrile (<b>(<i>S</i>)</b>-<b>15</b>, IC₅₀ value of 6 nM). Instead, only a subtle shift in the location of this water molecule resulted in a dramatic decrease in the energy of this high-energy hydration site, as shown by the WaterMap analysis combined with microsecond timescale molecular dynamics simulations. …”

Addressing a Trapped High-Energy Water: Design and Synthesis of Highly Potent Pyrimidoindole-Based Glycogen Synthase Kinase-3β Inhibitors by Stanislav Andreev (11067165)

“…Surprisingly, our results demonstrate that this high-energy water was not displaced by our potent inhibitor (<i>S</i>)-3-(3-((7-ethynyl-9<i>H</i>-pyrimido­[4,5-<i>b</i>]­indol-4-yl)­(methyl)­amino)­piperidin-1-yl)­propanenitrile (<b>(<i>S</i>)</b>-<b>15</b>, IC₅₀ value of 6 nM). Instead, only a subtle shift in the location of this water molecule resulted in a dramatic decrease in the energy of this high-energy hydration site, as shown by the WaterMap analysis combined with microsecond timescale molecular dynamics simulations. …”

Quizartinib decreased [¹²⁵I]-IAAP photolabeling of both ABCB1 and ABCG2 but inhibited ATPase activity of only ABCG2 at high concentrations. by Jasjeet Bhullar (445431)

Simultaneous silencing of isoamylases ISA1, ISA2 and ISA3 by multi-target RNAi in potato tubers leads to decreased starch content and an early sprouting phenotype by Stephanus J. Ferreira (4249219)

Knockdown of Smad3 led to increased expression and phosphorylation of IRS-1, which contributed to Smad3 knockdown-induced increased proliferation and decreased apoptosis under stre... by Katie L. Bailey (3929966)

The synthetic CB1R agonist WIN55,212–2 leads to decreased cell viability and increased G1 arrest in pancreatic β-cell lines. by Jihye Kim (344025)

miR-184 sensor expression across a range of tissues. by Sravya Paluri (5475260)

Propofol increased the number of the hippocampal pyramidal neurons and decreased the expression of the LC3-II protein and the number of lysosomes and autophagosomes in the ischemic... by Derong Cui (326839)

“…<p>I/R was induced by 2-vessel occlusion. Propofol 10, 50, or 100 mg/kg was administrated intraperitoneally and 3-MA (600 nM) was administered intracerebroventricularly 10 min after the onset of ischemia. (1) Sham-operated group (control group, Cont); (2) I/R group; (3) I/R+ 3-MA 600 nmol group; (4) I/R + propofol 10 mg/kg group; (5) I/R + propofol 50 mg/kg group; (6) I/R + propofol 100 mg/kg group; (7) I/R + vehicle (intralipid, 100 mg/kg) group. …”