DataSheet_1_The nasal microbiome in patients suffering from non-steroidal anti-inflammatory drugs-exacerbated respiratory disease in absence of corticosteroids.pdf by Tina J. Bartosik (9743316)

“…Although no significant difference in alpha and beta diversity was observed between the control and the CRS groups, pairwise testing revealed a higher relative abundance of Staphylococci in the middle meatus in N-ERD patients as compared to CRSwNP (p<0.001), CRSsNP (p<0.01) and disease controls (p<0.05) and of Lawsonella in patients suffering from CRSwNP in middle meatus and anterior naris in comparison to CRSsNP (p<0.0001 for both locations) and disease controls (p<0.01 and p<0.0001). Furthermore, we observed a positive correlation of Staphylococci with IL-5 (Pearson r=0.548) and a negative correlation for Corynebacteria and Eotaxin-3 (r=-0.540). …”

Image_1_The novel chimeric multi-agonist peptide (GEP44) reduces energy intake and body weight in male and female diet-induced obese mice in a glucagon-like peptide-1 receptor-depe... by James E. Blevins (11405813)

“…We hypothesized that GEP44 reduces energy intake and BW primarily through a GLP-1R dependent mechanism. …”

A Salmon Protein Hydrolysate Exerts Lipid-Independent Anti-Atherosclerotic Activity in ApoE-Deficient Mice by Cinzia Parolini (492973)

“…We investigated a salmon protein hydrolysate (SPH) that is hypothesized to influence lipid metabolism and to have anti-atherosclerotic and anti-inflammatory properties. 24 female apolipoprotein (apo) E^−/− mice were divided into two groups and fed a high-fat diet with or without 5% (w/w) SPH for 12 weeks. …”

Table1_House dust mite sublingual allergen immunotherapy tablet is safe and well-tolerated in Dutch clinical practice.docx by Žana Tempels-Pavlica (18073444)

“…CARAT scores improved clinically significant by 6 points and symptomatic medication use decreased from 96.1% to 77.4%. Most patients (74.5%) tolerated the treatment and were compliant (>86.5%). …”

SPI under <i>K</i> different distance ranges. by Thao Vu (3363083)

“…<p><i>K</i> values were incremented from 25 to 100 in steps of 5. At each <i>K</i>, a sequence of distance breaks was generated by linearly decreasing from <i>d</i>_<i>K</i> to 0 on a log scale. …”

Color maps of CT perfusion parameters. by Haifeng Shi (1742716)

“…<p>The BF value (E), BV value (F), MTT (G) and PS (H) maps for reperfusion of 4 h reveal that the BF, BV, and PS values are significantly decreased as compared to SO group(A-D). Microscopic ileal histology images show epithelial clefting, villi denudation (Chiu’s score 4) in IR groups (I, HE × 100).)…”

Impact of pathogen shedding characteristics on estimation accuracy. by Yun Lin (77976)

“…(C-F) trajectories of viral shedding until the time of detection for 200 randomly selected individuals infected with pathogen 1-4 corresponding to examples shown in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1013527#pcbi.1013527.g001" target="_blank">Fig 1C</a>, and in different epidemic periods as indicated in panel A (left panels: increasing epidemic, period 1; middle panels: epidemic peak, period 2; right panels: decreasing epidemic, period 3). …”

Image2_Hesperidin protects rats’ liver and kidney from oxidative damage and physiological disruption induced by nickel oxide nanoparticles.PNG by Ahmed Abd-Eltawab Tammam (12521617)

“…The first group served as a Control group. For 8 weeks, the second group was administered NiO-NPs (100 mg/kg/day), and the third group was given HSP (100 mg/kg/day) via oral gavage for both groups. …”

Image1_Hesperidin protects rats’ liver and kidney from oxidative damage and physiological disruption induced by nickel oxide nanoparticles.PNG by Ahmed Abd-Eltawab Tammam (12521617)

“…The first group served as a Control group. For 8 weeks, the second group was administered NiO-NPs (100 mg/kg/day), and the third group was given HSP (100 mg/kg/day) via oral gavage for both groups. …”

Transient and stable knock-down of ADAM10 suppresses APLP2 shedding. by Sebastian Hogl (349573)

“…All three species of sAPLP2 (* CS-GAG modified, ** 115 kDa, *** 100 kDa) were strongly decreased upon knock-down of ADAM10, but not of ADAM17. …”

Image_1_Autophagy-Related LC3 Accumulation Interacted Directly With LIR Containing RIPK1 and RIPK3, Stimulating Necroptosis in Hypoxic Cardiomyocytes.TIF by Yao Huang (216100)

“…Conversely, after alleviating hypoxia-induced autophagic flux impairment with LC3 or ATG5 knockdown adenovirus, the effects of hypoxia on RIPK1 and RIPK3 levels were reduced, which resulted in decreased p-RIPK3 and p-MLKL. …”

Image_2_Dietary patterns suggest that dark chocolate intake may have an inhibitory effect on oral cancer: a Mendelian randomization study.jpeg by Hongwei Wang (151141)

“…We extracted 21 dietary exposures, including 10 dietary patterns, 6 vitamins, and 5 micronutrients, from the UK Biobank database, using the inverse variance weighting method as the primary statistical method. …”

DataSheet_4_Doublecortin-Like Kinase 1 (DCLK1) Is a Novel NOTCH Pathway Signaling Regulator in Head and Neck Squamous Cell Carcinoma.pdf by Esther C. Broner (11145870)

“…<p>Despite recent advancements, the 5 year survival of head and neck squamous cell carcinoma (HNSCC) hovers at 60%. …”

DataSheet1_Thermo-Reversible Persistent Phosphorescence Modulation Reveals the Large Contribution Made by Rigidity to the Suppression of Endothermic Intermolecular Triplet Quenchin... by Tomoya Kusama (11711552)

“…(S)-(−)-2,2′-Bis(diphenylphosphino)-1,1′-binaphthyl ((S)-BINAP) was doped as a guest into a highly purified (S)-bis(diphenylphosphino)-5,5′,6,6′,7,7′,8,8′-octahydro-1,1′-binaphthyl ((S)-H₈-BINAP) host. …”

Genomics of Post-Prandial Lipidomic Phenotypes in the Genetics of Lipid Lowering Drugs and Diet Network (GOLDN) Study by Marguerite R. Irvin (102149)

“…</p><p>Methods and Results</p><p>We used gas chromatography mass spectrometry to quantify the change in plasma concentration of 35 fatty acids and 11 sterols between fasting and 3.5 hours after the consumption of a high-fat meal (PPL challenge) among 40 participants from the GOLDN study. …”

Distinct TCR repertoire in PIMS-TS/MIS-C patients: evidence for thymus involvement by Diana Yanez Marcayata (6785048)

“…We confirmed that human thymus explants can be infected with SARS-CoV-2 in vitro. …”

Image_1_Reassessing Particulate Organic Carbon Dynamics in the Highly Disturbed San Francisco Bay Estuary.TIF by Peter J. Hernes (8640351)

“…Across the ∼20-year span, we detected (1) decreasing C:N_a ratios (averages ± SD of 12.5 ± 2.5 vs. 8.8 ± 1.4, significant t-test with p < 0.0001); (2) distinct shifts in chlorophyll vs. salinity, with higher chlorophyll concentrations shifting toward freshwater; and (3) greater relative proportions of vascular plant carbon that also appears less degraded (as indicated by lignin measurements) shifting from freshwater toward higher salinities. …”

Table_2_Dietary patterns suggest that dark chocolate intake may have an inhibitory effect on oral cancer: a Mendelian randomization study.xlsx by Hongwei Wang (151141)

“…We extracted 21 dietary exposures, including 10 dietary patterns, 6 vitamins, and 5 micronutrients, from the UK Biobank database, using the inverse variance weighting method as the primary statistical method. …”

<i>Porphyromonas gingivalis</i> Evasion of Autophagy and Intracellular Killing by Human Myeloid Dendritic Cells Involves DC-SIGN-TLR2 Crosstalk by Ahmed R. El-Awady (697683)

“…Moreover, Mfa1+<i>P. gingivalis</i> was mostly contained within single membrane vesicles, where it survived intracellularly. Survival was decreased by activation of TLR2 and/or autophagy. Mfa1+<i>P. gingivalis</i> strain did not induce significant levels of Rab5, LC3-II, and LAMP1. …”

Image_4_A Potential Mechanism of Sodium Channel Mediating the General Anesthesia Induced by Propofol.tif by Jinglei Xiao (1422004)

“…Left shift of Na_V activation around a value of 5.5 mV in the thalamocortical models suppressed normal bursting of thalamocortical (TC) cells by triggering its chaotic oscillations. …”