Function and Evolution of DNA Methylation in <i>Nasonia vitripennis</i> by Xu Wang (28596)

“…<div><p>The parasitoid wasp <i>Nasonia vitripennis</i> is an emerging genetic model for functional analysis of DNA methylation. Here, we characterize genome-wide methylation at a base-pair resolution, and compare these results to gene expression across five developmental stages and to methylation patterns reported in other insects. …”

Leukemia Inhibitory Factor Protects Axons in Experimental Autoimmune Encephalomyelitis via an Oligodendrocyte-Independent Mechanism by Melissa M. Gresle (126963)

“…These mice also showed increased axonal damage relative to LIF heterozygous mice, as indicated by decreased optic nerve parallel diffusivity on MRI (1540±207 µm²−/s vs 1310±175 µm²−/s; P&lt;0.05), and optic nerve (−12.5%) and spinal cord (−16%) axon densities; and increased serum neurofilament-H levels (2.5 fold increase). …”

Table 1_Association of inflammatory biomarkers with new functional morbidity at hospital discharge in children who survive severe sepsis.docx by Mallory A. Perry-Eaddy (20842868)

“…</p>Results<p>New functional morbidity occurred in 38 children (32%) and was associated with increased plasma levels of interleukin (IL)-6, IL-18, sIL-2Ra, MCP1, IL-8 (CXCL8), sIL-1RII, IL-10, MIP1a, and IL-2r and decreased RANTES (CCL5) (p < .001) at all three timepoints. …”

DataSheet_1_Structural and functional alteration of the gut microbiota in elderly patients with hyperlipidemia.docx by Meng Xia (29894)

“…These groups were further subdivided by sex into the male normal (NM, n = 5), female normal (NF, n = 5), male hyperlipidemia (MM, n = 8), and female hyperlipidemia (MF, n = 8) subgroups. …”

Supplementary Material for: Calcium-citrate anticoagulation during continuous renal replacement therapy in patients with metformin intoxication: a case series, mathematical estimat... by Brunoni B. (16876404)

“…The T/I calcium ratio was consistently below 2.5, and SIG decreased, reaching values lower than 6 mEq/L after 48h of CVVH treatment. …”

Amphiphobic Polytetrafluoroethylene Membranes for Efficient Organic Aerosol Removal by Shasha Feng (2573317)

“…We use atomic-layer deposition (ALD) to uniformly coat a layer of nanosized ZnO particles onto porous PTFE matrix to increase surface area and then subsequently graft PFDAE with plasma. …”

PowerPoint Slides for: Repeated Renal Biopsy - A Predictive Tool to Assess the Probability of Renal Flare in Lupus Nephritis by Piñeiro G.J. (3290565)

“…Just after the repeated RB, 34.3% increased or started a new immunosuppressive therapy, 17.1% remained with the same complementary IST, and 14.3% decreased or stopped it. In the follow-up post repeated RB, 34.5% without active lesions showed a renal flare versus 77.8% with active lesions (p = 0.04). …”

Table_1_The prevalence and clustering of metabolic syndrome risk components in Chinese population: a cross-sectional study.docx by Xu Zhao (133907)

“…We evaluated the epidemiological characteristics of these components and their clustering conditions. …”

Image 1_Comparative analysis of gut microbiota in metabolic syndrome and obese children from Southeastern China.jpeg by Jingjing Wang (140791)

“…To investigate the differences in gut microbiota, we conducted physiological and biochemical assessments, alongside 16S rRNA sequencing, in a cohort of 32 children from Southeastern China, which included 4 normal-weight children, 5 with mild obesity, 9 with moderate obesity, 9 with severe obesity, and 5 with metabolic syndrome. …”

Hepatic irradiation persistently eliminates liver resident NK cells by Ryosuke Nakano (4557097)

“…This analysis demonstrated that hepatic irradiation decreased the number of liver resident NK cells (DX5^–TRAIL⁺), but did not affect the total NK number or proportions of NK cells in the liver or spleen. …”

Table_3_Sex and age effects on gray matter volume trajectories in young children with prenatal alcohol exposure.XLSX by Madison Long (18336297)

“…Using longitudinal T1-weighted MRI, the present study characterized gray matter volume development in young children with PAE (N = 42, 84 scans, ages 3–8 years) compared to unexposed children (N = 127, 450 scans, ages 2–8.5 years). Overall, we observed altered global and regional gray matter development trajectories in the PAE group, wherein they had attenuated age-related increases and more volume decreases relative to unexposed children. …”

Table_1_HPV Induces Changes in Innate Immune and Adhesion Molecule Markers in Cervical Mucosa With Potential Impact on HIV Infection.docx by Alan Messala A. Britto (6209393)

“…HPV infected patients expressed higher levels of TLR9 and lower levels of pattern recognition receptors that recognize RNA (TLR3, TLR7, and MDA5/IFIH1). We also detected an impaired IFN pathway, with an increased Type I IFN and a decreased IFNα2 receptor expression. …”

Data Sheet 1_Morphophysiological and transcriptomic analyses during the development of microspores and megaspores in Orobanche coerulescens.docx by Kelin Cui (20936231)

“…We also investigated the key regulatory genes in the metabolic pathways of phytohormones that are closely related to the development of microspores and megaspores using transcriptome sequencing technology.…”

Urbanization and translocation disrupt the relationship between host density and parasite abundance by Jayna L. DeVore (2927751)

“…We studied the interaction between the cane toad (Rhinella marina), a globally invasive species native to South America, and its Amblyomma ticks. …”

DataSheet1_Humanized CXCL12 antibody delays onset and modulates immune response in alopecia areata mice: insights from single-cell RNA sequencing.pdf by Seungchan An (6256061)

“…Gene ontology analysis revealed that immune cell chemotaxis and cellular response to type II interferon were upregulated in AA model but downregulated after Ab treatment. We further identified key immune cell-related genes such as Ifng, Cd8a, Ccr5, Ccl4, Ccl5, and Il21r, which were colocalized with Cxcr4 in T cells and regulated by CXCL12 Ab treatment. …”

Data Sheet 1_Epigenetic disruption of adipogenic gene enhancers in dedifferentiated liposarcomas and its therapeutic value.pdf by Naoko Hattori (491511)

“…First, we conducted a genome-wide DNA methylation analysis using 15 LPSs (6 WDLPSs and 9 DDLPSs) and 6 normal adipose tissues. …”

Data_Sheet_2_Plasma Oxylipins: A Potential Risk Assessment Tool in Atherosclerotic Coronary Artery Disease.docx by D. Elizabeth Le (10678956)

“…<p>Background: While oxylipins have been linked to coronary artery disease (CAD), little is known about their diagnostic and prognostic potential.</p><p>Objective: We tested whether plasma concentration of specific oxylipins may discriminate among number of diseased coronary arteries and predict median 5-year outcomes in symptomatic adults.…”

Table1_Humanized CXCL12 antibody delays onset and modulates immune response in alopecia areata mice: insights from single-cell RNA sequencing.xlsx by Seungchan An (6256061)

“…Gene ontology analysis revealed that immune cell chemotaxis and cellular response to type II interferon were upregulated in AA model but downregulated after Ab treatment. We further identified key immune cell-related genes such as Ifng, Cd8a, Ccr5, Ccl4, Ccl5, and Il21r, which were colocalized with Cxcr4 in T cells and regulated by CXCL12 Ab treatment. …”

A case study of density functional theory and domain-based local pair natural orbital coupled cluster for vibrational effects on EPR hyperfine coupling constants: vibrational pertu... by Alexander A. Auer (2348221)

“…Both approaches are found to yield very similar results for the spin probe 2,2,3,4,5,5-hexamethylperhydroimidazol-1-oxyl (HMI) and are both feasible for systems of around 30 atoms. …”

Data_Sheet_1_Plasma Oxylipins: A Potential Risk Assessment Tool in Atherosclerotic Coronary Artery Disease.docx by D. Elizabeth Le (10678956)

“…<p>Background: While oxylipins have been linked to coronary artery disease (CAD), little is known about their diagnostic and prognostic potential.</p><p>Objective: We tested whether plasma concentration of specific oxylipins may discriminate among number of diseased coronary arteries and predict median 5-year outcomes in symptomatic adults.…”