Altered glucose metabolism and hypoxic response in alloxan-induced diabetic atherosclerosis in rabbits by Yunosuke Matsuura (513639)

“…Diabetic atherosclerosis was induced in rabbit ilio-femoral arteries by injecting alloxan (100 mg/kg), injuring the arteries using a balloon, and feeding with a 0.5% cholesterol diet. We histologically assessed the atherosclerotic lesion development, cellular content, pimonidazole positive-hypoxic area, the nuclear localization of hypoxia-inducible factor-1α, and apoptosis. …”

Cellular Model of Warburg Effect Identifies Tumor Promoting Function of UCP2 in Breast Cancer and Its Suppression by Genipin by Vanniarajan Ayyasamy (205064)

“…We developed a MitoExpress array for rapid analysis of all known nuclear genes encoding the mitochondrial proteome. …”

Image_3_Combination Therapy of Mithramycin A and Immune Checkpoint Inhibitor for the Treatment of Colorectal Cancer in an Orthotopic Murine Model.tif by Rinku Dutta (2131366)

“…Tumors and spleens were analyzed by flow cytometry for the distinct immune cell populations affected by the treatment, in addition to RT-PCR for tumor samples. We demonstrated the combination treatment decreases tumor growth, thus increasing the effectiveness of the CB. …”

Image_1_Different Targets of Monoclonal Antibodies in Neuromyelitis Optica Spectrum Disorders: A Meta-Analysis Evidenced From Randomized Controlled Trials.JPEG by Tao Xue (488854)

“…Further, the subgroup analysis demonstrated that the anti-complement protein C5 monoclonal antibody (eculizumab) might have a lower relapse risk (RR 0.07, 95% CI 0.02–0.23, P < 0.0001) in the AQP4 seropositive patients, and anti-interleukin-6 receptor monoclonal antibodies (satralizumab and tocilizumab) showed decreased EDSS score (mean −0.17, 95% CI −0.31−0.02, P = 0.02) more effectively than other monoclonal antibodies.…”

Image_1_Heterogeneous Vancomycin-Intermediate Staphylococcus aureus Uses the VraSR Regulatory System to Modulate Autophagy for Increased Intracellular Survival in Macrophage-Like C... by Yuanyuan Dai (714579)

“…Mu3ΔvraSR-infected RAW264.7 cells also showed decreased transcription of autophagy-related genes Becn1 and Atg5, decreased LC3-II turnover and increased p62 degradation, and fewer visible punctate LC3 structures. …”

Image_2_Combination Therapy of Mithramycin A and Immune Checkpoint Inhibitor for the Treatment of Colorectal Cancer in an Orthotopic Murine Model.tif by Rinku Dutta (2131366)

“…Tumors and spleens were analyzed by flow cytometry for the distinct immune cell populations affected by the treatment, in addition to RT-PCR for tumor samples. We demonstrated the combination treatment decreases tumor growth, thus increasing the effectiveness of the CB. …”

Image_6_Combination Therapy of Mithramycin A and Immune Checkpoint Inhibitor for the Treatment of Colorectal Cancer in an Orthotopic Murine Model.tif by Rinku Dutta (2131366)

“…Tumors and spleens were analyzed by flow cytometry for the distinct immune cell populations affected by the treatment, in addition to RT-PCR for tumor samples. We demonstrated the combination treatment decreases tumor growth, thus increasing the effectiveness of the CB. …”

Image_4_Combination Therapy of Mithramycin A and Immune Checkpoint Inhibitor for the Treatment of Colorectal Cancer in an Orthotopic Murine Model.tif by Rinku Dutta (2131366)

“…Tumors and spleens were analyzed by flow cytometry for the distinct immune cell populations affected by the treatment, in addition to RT-PCR for tumor samples. We demonstrated the combination treatment decreases tumor growth, thus increasing the effectiveness of the CB. …”

Table_2_Heterogeneous Vancomycin-Intermediate Staphylococcus aureus Uses the VraSR Regulatory System to Modulate Autophagy for Increased Intracellular Survival in Macrophage-Like C... by Yuanyuan Dai (714579)

“…Mu3ΔvraSR-infected RAW264.7 cells also showed decreased transcription of autophagy-related genes Becn1 and Atg5, decreased LC3-II turnover and increased p62 degradation, and fewer visible punctate LC3 structures. …”

Supplementary Material for: Oxidative stress accompanies HIF1-dependent impairment of glucose metabolism in the hippocampus of adult rats survived prenatal severe hypoxia by Vetrovoy O. (17409348)

“…Introduction: Many socially significant diseases are associated with prenatal developmental disorders. Previously, we showed the pathological role of hypoxia-inducible factor HIF1 in post-hypoxic reoxygenation. …”

Evaluation of Bite Force and Masticatory Performance: Complete Denture vs Mandibular Overdenture Users by Anna Paula da Rosa Possebon (10439900)

“…IMO users presented significantly higher BF (p=0.01) without presenting a dominant side (p=0.38), and also performed significantly better for the following MP parameters: MPX50 values decreased by 27.25% in IMO users (p=0.01), MPB decreased by 48.38% (p=0.01), and ME 5.6 decreased by 53.25% (p=0.02), while ME2.8 increased by 151.57% (p=0.01). …”

Table_1_Research on the effects of rs1800566 C/T polymorphism of NAD(P)H quinone oxidoreductase 1 gene on cancer risk involves analysis of 43,736 cancer cases and 56,173 controls.d... by Hangsheng Zhou (7305830)

Can heat waves change the trophic role of the world’s most invasive crayfish? Diet shifts in <i>Procambarus clarkii</i> by Bruno M. Carreira (4413205)

Image_1_Research on the effects of rs1800566 C/T polymorphism of NAD(P)H quinone oxidoreductase 1 gene on cancer risk involves analysis of 43,736 cancer cases and 56,173 controls.t... by Hangsheng Zhou (7305830)

The most important microhabitats for taxa that tested without significant habitat associations in the AICc analysis in distLM Permanova+, Primer-e v7. by Christopher J. Thorpe (5007689)

“…Population stability:/S-Stable; /D-Decreasing; /I-Increasing. RH-Relative Humidity; Rock -large loose rocks >50 mm; Rock N-abundance of small rocks<50 mm; Plant-%of area with woody plant cover; Soil-% of area with soil; Stream-stream in surveyed area; Pool-lentic pools within surveyed area; Flood-plateau surface flooded to a depth >25 mm; Agree-our habitat association agree with published findings; Elev-altitude above sea leavel taxa were found; Habitat Associations are those listed by the IUCN.…”

The strategic persistence of users. by Lingfei Wu (453300)

“…In Panel D and F we only present the data of the users who contribute to more than three communities as otherwise <i>H</i>_<i>i</i> would trivially equals 1 (if a user only contributes to one community) or switches between 0.5 and 1 (if a user only contributes to two communities). …”

Linking functional subgraphs to neuroanatomy of canonical cognitive systems. by Ankit N. Khambhati (838251)

“…For system-by-system adjacency matrix representations of functional subgraphs, we refer the reader to <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1006234#pcbi.1006234.s005" target="_blank">S5 Fig</a>. …”

Defective basal immune gene expression and p38 MAP kinase activation in the <i>fat-3(wa22)</i> mutant. by Madhumitha Nandakumar (269242)

“…<p>Expression of 12 infection- and stress-response genes under normal growth (A) and infection (B) conditions. mRNA expression was quantified by qRT-PCR in wild-type, <i>fat-3(wa22)</i> and <i>sek-1(km4)</i> 1-day-old adults exposed to OP50-1 (A) or PA14 (B) for 12 h. …”

Image_1_Substrate Stiffness Regulates Cholesterol Efflux in Smooth Muscle Cells.pdf by Xiuli Mao (7819301)

Model selection and goodness-of-fit of the full HLB spread in the Lower Rio Grande Valley, Texas. by Viet-Anh Nguyen (137745)

“…Besides the medians of 1000 simulation realizations (solid lines), we also show 50%, 75%, and 95% credible intervals (shades of decreasing intensities). …”