Differentially expressed genes in <i>pgl</i> vs WT. by Jisun Kim (837555)

“…These differences were also evident through unbiased metabolomics studies and ¹³C labeling experiments that showed mutation of <i>pgl</i> led to reductions in pyrimidine metabolism including decreases in ribose-5P, UMP and GMP. These nucleotide reductions impacted the amount of extracellular DNA in biofilms and reduced biofilm formation. …”

Data_Sheet_1_Are There Advantages to Believing in Fate? The Belief in Negotiating With Fate When Faced With Constraints.docx by Evelyn W. M. Au (7837178)

“…Subsequent studies found that after recalling a constraining event, exposure to the belief in negotiating with fate (but not exposure to fatalism) decreased repetitive thoughts (Experiment 3), increased the conviction that personal actions contributed to the event (Experiment 4), increased acceptance and positive reinterpretation of the event (Experiment 5), and increased how meaningful the event was (Experiment 6). …”

Image1_The Membrane Cholesterol Modulates the Interaction Between 17-βEstradiol and the BK Channel.pdf by Sara T. Granados (8613093)

“…It has been shown that the estrogen 17β-Estradiol (E2) causes a vasodilator effect in vascular cells, inducing a leftward shift in the V_0.5 of the GV curve. Here, we evaluate whether changes in the membrane cholesterol concentration modify the effect that E2 induces on the BKα/β1 channel activity. …”

Data_Sheet_1_β-secretase inhibition prevents structural spine plasticity deficits in AppNL-G-F mice.docx by Tanja Blume (5347112)

“…We conducted in vivo two-photon microscopy in the stratum oriens layer of hippocampal CA1 neurons in 3.5-month-old App^NL-G-FGFP-M mice over 6 weeks to monitor the effect of potential preventive treatment with a high and low dose of the BACE1-inhibitor NB-360 on dendritic spine dynamics. …”

Data_Sheet_1_Use of 3D modeling to refine predictions of canopy light utilization: A comparative study on canopy photosynthesis models with different dimensions.docx by Shenghao Gu (7292960)

“…We found crop yield predictions decreased by 12.0–48.5% with increasing the resolution of light simulation, suggesting that a crop growth model without architectural details may result in a considerable departure from the actual photosynthetic production. …”

Table_2_Tidal zone effects on the diet composition of leaf-eating crabs in natural mangrove communities: a stable isotope analysis.xlsx by Xiaoyan Lu (226200)

“…We conducted experiments at various tidal levels in the Dongzhaigang Bay National Natural Reserve in China. …”

Image_2_Human B-1 Cells and B-1 Cell Antibodies Change With Advancing Age.TIF by Nely Rodriguez-Zhurbenko (6477113)

“…Our results show that not only the percentage of B-1 cells but also their ability to spontaneously secrete IgM decreased with age. Further, expression levels of the transcription factors XBP-1 and Blimp-1 were significantly lower, while PAX-5, characteristic of non-secreting B cells, was significantly higher, in healthy donors over 65 years (old) as compared to healthy donors between 20 and 45 years (young). …”

DataSheet_1_Ascorbate Inhibits Proliferation and Promotes Myeloid Differentiation in TP53-Mutant Leukemia.pdf by Carlos C. Smith-Díaz (11312490)

“…We found that the addition of ascorbate had a minimal effect on Prima-1^Met–induced cytotoxicity, with small increases or decreases in cytotoxicity being observed depending on the timing of treatment. …”

Table_1_Responses of terrestrial ecosystem productivity and community structure to intra-annual precipitation patterns: A meta-analysis.xlsx by Mingyu Xie (13868310)

“…</p>Results<p>Our results showed that the intra-annual precipitation patterns decreased diversity by 6.3% but increased belowground net primary productivity, richness, and relative abundance by 16.8%, 10.5%, and 45.0%, respectively. …”

Table_3_Spatiotemporal Variations in Seed Set and Pollen Limitation in Populations of the Rare Generalist Species Polemonium caeruleum in Poland.DOCX by Justyna Ryniewicz (11893103)

“…During a 5-year study in several populations of P. caeruleum (7–15, depending on year), we assessed the degree of pollen limitation based on differences in seed set between open-pollinated (control) and hand-pollinated flowers. …”

Table_3_Tidal zone effects on the diet composition of leaf-eating crabs in natural mangrove communities: a stable isotope analysis.xlsx by Xiaoyan Lu (226200)

“…We conducted experiments at various tidal levels in the Dongzhaigang Bay National Natural Reserve in China. …”

Data_Sheet_1_Mutations identified in engineered Escherichia coli with a reduced genome.PDF by Yuto Kotaka (15907688)

“…Interestingly, a SNV was identified in the promoter region of hcaT in all five strains, which increased hcaT expression and, we predict, rescued the attenuated Δ37b growth. …”

Kinetic Evaluation of Photosensitivity in Bi-Stable Variants of Chimeric Channelrhodopsins by Shoko Hososhima (392575)

“…<div><p>Channelrhodopsin-1 and 2 (ChR1 and ChR2) form cation channels that are gated by light through an unknown mechanism. We tested the DC-gate hypothesis that C167 and D195 are involved in the stabilization of the cation-permeable state of ChRWR/C1C2 which consists of TM1-5 of ChR1 and TM6-7 of ChR2 and ChRFR which consists of TM1-2 of ChR1 and TM3-7 of ChR2. …”

Image_1_MicroRNA-5112 Targets IKKγ to Dampen the Inflammatory Response and Improve Clinical Symptoms in Both Bacterial Infection and DSS-Induced Colitis.tif by Xilong Kang (2548195)

“…However, the role of miRNAs in inflammation induced by flagellin (ligand of TLR5) has yet to be fully determined. In this study, we identified differentially expressed miRNAs in murine bone marrow-derived dendritic cells (BMDCs) between flagellin treatment and medium alone using miRNA microarray. …”

Detecting conservation benefits of marine reserves on remote reefs of the northern GBR by Carolina Castro-Sanguino (4579024)

“…As expected, the biomass of targeted fish species was generally greater (up to 5-fold) in no-take zones than in fished zones, but we found no differences between the two forms of no-take zone: ‘no-take’ versus ‘no-entry’. …”

Table_1_MicroRNA-5112 Targets IKKγ to Dampen the Inflammatory Response and Improve Clinical Symptoms in Both Bacterial Infection and DSS-Induced Colitis.docx by Xilong Kang (2548195)

“…However, the role of miRNAs in inflammation induced by flagellin (ligand of TLR5) has yet to be fully determined. In this study, we identified differentially expressed miRNAs in murine bone marrow-derived dendritic cells (BMDCs) between flagellin treatment and medium alone using miRNA microarray. …”

STA regulates succinylated AflM triggered by SCS to contribute to aflatoxin biosynthesis through the Ach1 by Rui Xie (826938)

“…Succinyl-CoA synthase ADP-forming subunit β (SCS) is involved in the synthesis of succinate from succinyl-CoA in the tricarboxylic acid cycle. In this study, we demonstrated that SCS led to decreased aflatoxin production. …”

Image_1_Tidal zone effects on the diet composition of leaf-eating crabs in natural mangrove communities: a stable isotope analysis.jpeg by Xiaoyan Lu (226200)

“…We conducted experiments at various tidal levels in the Dongzhaigang Bay National Natural Reserve in China. …”

Data_Sheet_1_Ductal Mucus Obstruction and Reduced Fluid Secretion Are Early Defects in Chronic Pancreatitis.PDF by Anita Balázs (3239238)

“…Secretory mucins MUC6 and MUC5B were upregulated in human, Muc6 in mouse CP. …”

Tor Signaling Regulates Transcription of Amino Acid Permeases through a GATA Transcription Factor Gaf1 in Fission Yeast by Yan Ma (88810)

“…The loss of Tor1 decreased, and Tor2 inhibition by its temperature sensitive mutation increased, mRNA expression of <i>isp5</i>^<i>+</i>, <i>per1</i>^<i>+</i>, <i>put4</i>^<i>+</i> and <i>SPBPB2B2</i>.…”