Image_2_Aggregatibacter actinomycetemcomitans cytolethal distending toxin modulates host phagocytic function.tiff by Taewan J. Kim (16910679)

“…Phosphoinositides, also play a critical role in phagosome trafficking, serving as binding domains for effector proteins during phagosome maturation and subsequent fusion with lysosomes. We now demonstrate that AaCdt manipulates the phosphoinositide (PI) pools of phagosome membranes and alters Rab5 association. …”

Linagliptin does not increase catalase and MnSOD mRNA but trends to increase catalase protein level while significantly enhancing MnSOD protein level in G6PD^- mouse kidn... by Netanya Y. Spencer (5488931)

Decision boundary dynamics modulated by theta activity. by Nadja R. Ging-Jehli (10925910)

“…view_only=5c442294fcfb4991bb42cd902c60249c" target="_blank">https://osf.io/k38pj/?…”

Mouse models for hereditary spastic paraplegia uncover a role of PI4K2A in autophagic lysosome reformation by Mukhran Khundadze (499790)

“…The respective proteins play a role for macroautophagy/autophagy and autophagic lysosome reformation (ALR). Here, we report that <i>spg11</i> and <i>zfyve26</i> KO mice developed motor impairments within the same course of time. …”

Metformin enhances epithelial cell growth inhibition via the protein kinase–insulin-like growth factor binding protein-1 pathway by Xuping Shao (18136294)

“…In an EcSC IGFBP1 overexpression model, the ability of EcSCs to inhibit epithelial cell proliferation was enhanced (EdU positivity decreased from 38% to 25%, <i>p</i> = .0001). Furthermore, adenosine 5’-monophosphate-activated protein kinase (AMPK) phosphorylation was downregulated in EcSCs and EuSCs compared to that in NSCs (0.99 vs. 0.42, <i>p</i> = .0006/0.99 vs. 0.57, <i>p</i> = 0.0032). …”

Datasheet1_Assessing sustainment of health worker outcomes beyond program end: Evaluation results from an infant and young child feeding intervention in Bangladesh.docx by Corrina Moucheraud (439348)

“…Introduction<p>Alive and Thrive (A&T) implemented infant and young child feeding (IYCF) interventions in Bangladesh. We examine the sustained impacts on health workers' IYCF knowledge, service delivery, job satisfaction, and job readiness three years after the program's conclusion.…”

DataSheet_1_The nasal microbiome in patients suffering from non-steroidal anti-inflammatory drugs-exacerbated respiratory disease in absence of corticosteroids.pdf by Tina J. Bartosik (9743316)

“…Although no significant difference in alpha and beta diversity was observed between the control and the CRS groups, pairwise testing revealed a higher relative abundance of Staphylococci in the middle meatus in N-ERD patients as compared to CRSwNP (p<0.001), CRSsNP (p<0.01) and disease controls (p<0.05) and of Lawsonella in patients suffering from CRSwNP in middle meatus and anterior naris in comparison to CRSsNP (p<0.0001 for both locations) and disease controls (p<0.01 and p<0.0001). Furthermore, we observed a positive correlation of Staphylococci with IL-5 (Pearson r=0.548) and a negative correlation for Corynebacteria and Eotaxin-3 (r=-0.540). …”

Image 2_Dietary risk factors and cancer mortality burden from 1990 to 2021: a comparative study of China and global regions with varying sociodemographic development levels based o... by Chunxiu Zhao (21650204)

“…</p>Results<p>Diet-attributable cancer deaths in China decreased from 9.9% (95% CI: 2.2–20.5%) to 6.3% (95% CI: 2.1–12.8%) during 1990–2021. …”

A Salmon Protein Hydrolysate Exerts Lipid-Independent Anti-Atherosclerotic Activity in ApoE-Deficient Mice by Cinzia Parolini (492973)

“…We investigated a salmon protein hydrolysate (SPH) that is hypothesized to influence lipid metabolism and to have anti-atherosclerotic and anti-inflammatory properties. 24 female apolipoprotein (apo) E^−/− mice were divided into two groups and fed a high-fat diet with or without 5% (w/w) SPH for 12 weeks. …”

Data Sheet 1_Dietary risk factors and cancer mortality burden from 1990 to 2021: a comparative study of China and global regions with varying sociodemographic development levels ba... by Chunxiu Zhao (21650204)

“…</p>Results<p>Diet-attributable cancer deaths in China decreased from 9.9% (95% CI: 2.2–20.5%) to 6.3% (95% CI: 2.1–12.8%) during 1990–2021. …”

Image 1_Dietary risk factors and cancer mortality burden from 1990 to 2021: a comparative study of China and global regions with varying sociodemographic development levels based o... by Chunxiu Zhao (21650204)

“…</p>Results<p>Diet-attributable cancer deaths in China decreased from 9.9% (95% CI: 2.2–20.5%) to 6.3% (95% CI: 2.1–12.8%) during 1990–2021. …”

Table1_House dust mite sublingual allergen immunotherapy tablet is safe and well-tolerated in Dutch clinical practice.docx by Žana Tempels-Pavlica (18073444)

“…CARAT scores improved clinically significant by 6 points and symptomatic medication use decreased from 96.1% to 77.4%. Most patients (74.5%) tolerated the treatment and were compliant (>86.5%). …”

Image 3_Dietary risk factors and cancer mortality burden from 1990 to 2021: a comparative study of China and global regions with varying sociodemographic development levels based o... by Chunxiu Zhao (21650204)

“…</p>Results<p>Diet-attributable cancer deaths in China decreased from 9.9% (95% CI: 2.2–20.5%) to 6.3% (95% CI: 2.1–12.8%) during 1990–2021. …”

Wheat Grain Biomechanics Data by James Hourston (2808649)

“…Finally, the force displacement curves were interpreted and classified as to the breaking behaviour (failure type). We split this biological material into three discrete categories of breaking behaviour a) a “brittle” failure; force increases until a sudden complete failure takes place b) a “composite” failure; a step-by step failure, creating a typical “zig-zag” pattern and finally c) a “continuous” failure; typified by a continuous decrease in force without sudden drops or steps. …”

Tumor-suppression by AQHAR treatment in nude mice tumor xenograft assays. by Kejuan Li (2580184)

Lithium treatment effect on blood plasma metabolome. Metabolic network of wild-type and <i>Sca1^154Q/+</i> plasma phenotypes. by Bertrand Perroud (280954)

UPPAAL SMC model specification by Marc Souvannasouck (16475829)

“…Upon the completion of this month, the model transitions to a branchpoint and adds a monthly cost of 50 to the total cost, denoting a constant monthly expense for treatment management. …”

Characterization of Adherent Bacteroidales from Intestinal Biopsies of Children and Young Adults with Inflammatory Bowel Disease by Naamah L. Zitomersky (420427)

Image_1_Fpr2/CXCL1/2 Controls Rapid Neutrophil Infiltration to Inhibit Streptococcus agalactiae Infection.tif by Zeyu Sun (2932719)

Supplementary file 1_Characterizing rainfall patterns and dynamics in the Little Ruaha catchment, southern Tanzania.docx by Florence H. Mahay (22374706)

“…The results indicate that rain-fed crops in the southern and northeastern regions of the catchment are highly susceptible to drought stress, particularly during the short rainfall season (20% probability). Furthermore, there is a significant risk of water stress for sensitive crops in a typical season (50% probability) in these areas. …”