Wnt signaling decreases the recruitment of RAB8a to basal bodies. by Cheng Yuan (160315)

EtOH decreased ΔΨm in a subset of esophageal keratinocytes. by Prasanna M. Chandramouleeswaran (3176268)

RNF5 loss decreases PEL xenograft tumor growth and cell cycle gene expression. by Xiaojuan Li (351842)

Cardamonin decreased the content of free fatty acids and the activity of CPT-1. by Peiguang Niu (17044532)

19606 decreases the luminal pH of the ACV during infection. by Jesus S. Distel (11250759)

Cardamonin decreased the protein level of Raptor and suppressed lipogenesis and CPT-1. by Peiguang Niu (17044532)

Pro- and anti-inflammatory cytokines are significantly decreased at acute time points following IR. by Jordan A. Gunning (18143970)

Disruption of putative host factor LGMN decreases SARS-CoV-2 viral entry. by Ravi K. Dinesh (21736629)

Structure–Activity Relationship of 3‑Methylcytidine-5′-α,β-methylenediphosphates as CD73 Inhibitors by Mirko Scortichini (4007366)

“…We now expand the structure–activity relationship of pyrimidine nucleotides as human CD73 inhibitors. 4-Chloro (MRS4598 <b>16</b>; <i>K</i>_i = 0.673 nM) and 4-iodo (MRS4620 <b>18</b>; <i>K</i>_i = 0.436 nM) substitution of the <i>N</i>⁴-benzyloxy group decreased <i>K</i>_i by ∼20-fold. …”

Structure–Activity Relationship of 3‑Methylcytidine-5′-α,β-methylenediphosphates as CD73 Inhibitors by Mirko Scortichini (4007366)

“…We now expand the structure–activity relationship of pyrimidine nucleotides as human CD73 inhibitors. 4-Chloro (MRS4598 <b>16</b>; <i>K</i>_i = 0.673 nM) and 4-iodo (MRS4620 <b>18</b>; <i>K</i>_i = 0.436 nM) substitution of the <i>N</i>⁴-benzyloxy group decreased <i>K</i>_i by ∼20-fold. …”

Structure–Activity Relationship of 3‑Methylcytidine-5′-α,β-methylenediphosphates as CD73 Inhibitors by Mirko Scortichini (4007366)

“…We now expand the structure–activity relationship of pyrimidine nucleotides as human CD73 inhibitors. 4-Chloro (MRS4598 <b>16</b>; <i>K</i>_i = 0.673 nM) and 4-iodo (MRS4620 <b>18</b>; <i>K</i>_i = 0.436 nM) substitution of the <i>N</i>⁴-benzyloxy group decreased <i>K</i>_i by ∼20-fold. …”

HSP90 inhibition by RGRN-305 decreased the gene expression of proinflammatory cytokines induced by SARS-CoV-2 S protein. by Hakim Ben Abdallah (14578241)

5-HT supplementation inhibits mitophagy. by Li Gao (131516)

Depletion of putative SDH subunits leads to decreased SDH activity and oxygen consumption. by Mariana F. Silva (10219520)

B2 decreases glycolytic intermediates in cells. by Craig Eyster (392633)

“…<b>(C)</b> Heatmap of targeted metabolomic data. Each column is a separate biological replicate (n = 5). The box indicates the clustering of decreased downstream glycolytic intermediates in B2-treated cells. …”

Madrasin decreases transcription of protein-coding genes. by Michael Tellier (8284752)

Decreasing mean transistor size since 2000. by David Burg (8209752)

Maximum IFN concentrations are decreased in severe patients. by Sonia T. Gazeau (21512764)

Madrasin decreases transcription of protein-coding genes. by Michael Tellier (8284752)

Inhibition of Hsp90 decreased cellular apoptosis. by Raúl Orozco-Díaz (7067624)