Discovery of the Triazolo[1,5‑<i>a</i>]Pyrimidine-Based Derivative WS-898 as a Highly Efficacious and Orally Bioavailable ABCB1 Inhibitor Capable of Overcoming Multidrug Resistance... by Shuai Wang (109515)

“…Here, we reported our medicinal chemistry efforts that led to the discovery of the triazolo­[1,5-<i>a</i>]­pyrimidine derivative <b>WS-898</b> as a highly effective ABCB1 inhibitor capable of reversing paclitaxel (PTX) resistance in drug-resistant SW620/Ad300, KB-C2, and HEK293/ABCB1 cells (IC₅₀ = 5.0, 3.67, and 3.68 nM, respectively), more potent than verapamil and zosuquidar. …”

All indicator plants’ mean EC₅₀ values for seed germination, radicle, and hypocotyl length are represented in a dendrogram (C₁- Bambara groundnut, C<sub>2</su... by H. M. Khairul Bashar (14341613)

Fig 9 - by Dennis Ochola (11626912)

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Correlation between protein abundances and R_5-20 z-score among cases at baseline. Protein abundances, normalized to mean 0 and variance 1, are displayed on the y-axis. (... by Spela Kokelj (8356644)

Fig 4 - by Dennis Ochola (11626912)

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Absence of neocortex is associated with a dorsal shift of piriform cortex in <i>Emx1</i>-cKO mice. by Sathish Venkataramanappa (10331993)

Split <i>ClvR</i>^<50cM configurations. by Georg Oberhofer (3401438)

50 most upregulated genes in AzEvC10 during macrophage infection. by Mylene Vaillancourt (7409486)

CcnA mutation of Loop A decreases the interaction with the 5′ UTR of P2-<i>ctrA</i> mRNA and 5′ UTR of <i>gcrA</i> mRNA. by Wanassa Beroual (5314028)

Overexpression of TNFAIP9 remitted the renal inflammation caused by 5/6 Nx in C57 mice. by Ying Chen (9697)

Overexpression of TNFAIP9 counteracted the renal damage caused by 5/6 Nx in C57 mice. by Ying Chen (9697)

HPLC METHOD IMPROVEMENT FOR 4-NONYLPHENOL DETERMINATION IN ANAEROBIC REACTORS: DECREASING SOLVENT CONSUMPTION AND WASTE GENERATION by Henrique S. Dornelles (10381255)

GXM decreases the trans-endothelial electrical resistance (TEER) and transmigration of <i>C</i>. <i>neoformans</i> through HBECs in a blood brain barrier (BBB) model. by Hiu Ham Lee (15374677)

Claudin V is decreased following infection with Mtb. by Amanda S. Latham (12093638)

“…Exposure to Mtb H37Rv and HN878 decreased claudin V expression compared to uninfected controls in the frontal cortex (E), cerebral nuclei (J), brain stem (O), thalamus (T), and hippocampus (Y). …”

Ivermectin significantly decreases <i>L</i>. <i>loa</i> mf in BALB/c mice. by Rene Bilingwe Ayiseh (6900296)

<i>RTTN</i>-mutated organoids exhibit decreased proliferation and increased cell death at early stages. by Justine Guguin (9088672)

Ppk1 levels are not affected by decreasing dendrite arbor size but are reduced when dendrite length increases. by Josephine W. Mitchell (17364781)

The mean (+ s.e.m.) change of CD169 expression levels on CD14⁺ monocytes in blood of rhesus macaques stratified by time of cART initiation. by Brandon F. Keele (7450001)

S5 Data - by Ayuta Kishimoto (16814662)

Atomically Precise Au₄₂ Nanorods with Longitudinal Excitons for an Intense Photothermal Effect by Yingwei Li (701628)

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