The hypothalamic-pituitary-thyroid axis in TRH deficient mice. by Yasuyo Nakajima (316579)

“…TRHKO (n = 7) were supplemented with thyroid hormone by the daily injection of T4 (1.5 μg/100 g body weight) for 14 days to be euthyroid (n = 6). …”

Data_Sheet_1_Analysis of the Dose-Response Effects of Physical Activity on Cardiocerebrovascular and All-Cause Mortality in Hypertension.docx by Jun-Peng Xu (12254186)

“…Subgroup analysis and restricted cubic spline curves showed that MV-PA surpassing 15 MET-h/week could decrease the risks of cardiovascular and all-cause mortality with inverse relationships, which was not the case for cerebrovascular mortality, indicating a U-shaped association.…”

De-identified data. by Sophie Wennemann (17936137)

“…There was a decrease in EQ-VAS scores for heavy (adj. p = 0.007) and light (adj. p = 0.017) exposure groups compared to no reported exposure, indicating lower perceptions of overall health. …”

Data_Sheet_1_Systematic assessment of clinical and bacteriological markers for tuberculosis reveals discordance and inaccuracy of symptom-based diagnosis for treatment response mon... by Bariki Mtafya (349098)

“…A decrease in TB-MBLA positivity reflected a fall in bacillary load, 5.7 ± 1.3- at baseline to 0.30 ± 1.0- log₁₀ eCFU/ml at month 6, and closer to cough resolution than other bacteriological measures, accounting for the only one bacteriologically positive case out of seven still coughing at month 6. …”

iPD strategies in the final population. by Anton M. Unakafov (5706560)

“…(C) Entries <i>s</i>₉, …, <i>s</i>₁₂ are irrelevant for <i>p</i>_see = 0.0 (resulting in random values around 0.5) and are quite low for <i>p</i>_see = 0.1, …, 0.3 (<i>s</i>₁₂ is irrelevant in a cooperative population). …”

Image_1_Angiotensin-(1-7) improves cognitive function and reduces inflammation in mice following mild traumatic brain injury.JPEG by Ryan P. Bruhns (13197621)

“…Introduction<p>Traumatic brain injury (TBI) is a leading cause of disability in the US. Angiotensin 1-7 (Ang-1-7), an endogenous peptide, acts at the G protein coupled MAS1 receptors (MASR) to inhibit inflammatory mediators and decrease reactive oxygen species within the CNS. …”

Data_Sheet_1_Systematic assessment of clinical and bacteriological markers for tuberculosis reveals discordance and inaccuracy of symptom-based diagnosis for treatment response mon... by Bariki Mtafya (349098)

“…A decrease in TB-MBLA positivity reflected a fall in bacillary load, 5.7 ± 1.3- at baseline to 0.30 ± 1.0- log₁₀ eCFU/ml at month 6, and closer to cough resolution than other bacteriological measures, accounting for the only one bacteriologically positive case out of seven still coughing at month 6. …”

HO-1 induction increases HO-1, AKT and GSK3β expression in diabetic hearts. by Yossi Issan (540887)

“…<p>A:CoPP treatment significantly increased HO-1 expression levels (Means ± SD, n = 5. …”

NMR analyses of the HPV16 E6/E6APpep and HPV16 E6/pep11** interactions. by Katia Zanier (17371)

“…Note that in the case of spectra of E6/pep11** samples some signals have lower intensity in the red spectrum than in the cyan spectrum (see enlarged view of lower panel). This decrease in signal intensity is concomitant with the appearance of a white precipitate of E6 in the NMR tube. …”

DataSheet_1_TCRβ clones in muscle tissue share structural features in patients with idiopathic inflammatory myopathy and are associated with disease activity.docx by Dornatien C. Anang (17765313)

“…</p>Methods<p>High throughput RNA sequencing of the TCRβ chain was performed in peripheral blood and muscle tissue in twenty newly-diagnosed treatment-naïve IIM patients (9 DM, 5 NM/OM, 5 IMNM and 1 ASyS) and healthy controls. …”

Synthesis, Crystal Structure, EPR and DFT Studies, and Redox Properties of [2]Tetramethyldisilacobaltocenophane by Holger Braunschweig (1370640)

“…As was shown by cyclic voltammetry in THF, <b>1</b> is quasi-reversibly oxidized to the neutral cobaltocenium cation [(Me₂Si)₂(η⁵-C₅H₄)₂Co]⁺ (<b>8</b>) at a potential of <i>E</i>°_1/2 = −1.27 V (vs the Fc/Fc⁺ couple) and quasi-reversibly reduced to the corresponding anion [(Me₂Si)₂(η⁵-C₅H₄)₂Co]⁻ (<b>9</b>) at <i>E</i>°_1/2 = −2.40 V. …”

Synthesis, Crystal Structure, EPR and DFT Studies, and Redox Properties of [2]Tetramethyldisilacobaltocenophane by Holger Braunschweig (1370640)

“…As was shown by cyclic voltammetry in THF, <b>1</b> is quasi-reversibly oxidized to the neutral cobaltocenium cation [(Me₂Si)₂(η⁵-C₅H₄)₂Co]⁺ (<b>8</b>) at a potential of <i>E</i>°_1/2 = −1.27 V (vs the Fc/Fc⁺ couple) and quasi-reversibly reduced to the corresponding anion [(Me₂Si)₂(η⁵-C₅H₄)₂Co]⁻ (<b>9</b>) at <i>E</i>°_1/2 = −2.40 V. …”

N-Glycomic Changes in Serum Proteins in Type 2 Diabetes Mellitus Correlate with Complications and with Metabolic Syndrome Parameters by Roberto Testa (218036)

“…</p><p>Methods</p><p>We enrolled in the study 562 patients with Type 2 Diabetes Mellitus (T2DM) (mean age 65.6±8.2 years) and 599 healthy control subjects (CTRs) (mean age, 58.5±12.4 years). …”

Inhibition of glycolysis phenocopies the yeast-dependent modulation of arousal threshold. by Elizabeth B. Brown (4582978)

“…(G) Although there is a significant effect of treatment arousal threshold (REML: F_1,121 = 5.426, <i>P</i><0.0231, N = 46–51), <i>post hoc</i> analyses revealed no evidence of a homeostatic rebound for any timepoint measured (0–3 hrs: <i>P</i> = 0.3274; 0–6 hrs: <i>P</i> = 0.0822; 0–12 hrs: <i>P</i> = 0.4670). …”

Knockdown of mDia formins impairs oocyte maturation and spindle formation. by Hak-Cheol Kim (716627)

“…</b> Knockdown of mDia1, mDia2, or mDia1 + mDia2 decreases the oocyte maturation rate and increases the symmetric division rate. dsRNA against mDia1, mDia2, or a mixture of mDia1 and mDia2 were microinjected into immature oocytes along with control dsRNA and cells were cultured for 12 h after which their status of development was assessed. …”

UA treatment reduces PMA-induced ear edema and MPO activity. by Piu Saha (323459)

“…<p>Mice (n = 5) were orally gavaged with vehicle control (10% glucose), UA (40 mg/kg body weight), EA (40 mg/kg body weight) and indomethacin (10 mg/kg body weight) at 2 hrs prior to applying PMA to right ear and acetone (control) to the left ear. …”

Expression analysis of TNF-α, COX-2 and GAPDH by RT-PCR. by Bharathi Raja Subramaniya (352251)

“…<p>Lane 1- Control HCT15; Lane 2- 15 µM plumbagin treated HCT15; Lane 3- 30 µM plumbagin treated HCT15; Lane 4- Control HT29; Lane 5- 50 µM plumbagin treated HT29; Lane 6- 75 µM plumbagin treated HT29. a. …”

Quality of sleep in pregnant woman with low back pain by Vanessa Patrícia Soares de Sousa (4958455)

“…Sleep quality was lower in SG (8.21 ± 4.8) when compared to CG (5.94 ± 1.7) and was statistically significant (P = 0.021). …”

Galiellalactone induces apoptosis and inhibits proliferation of ALDH+ prostate cancer cells. by Rebecka Hellsten (348459)

“…<p>A. ALDH+ and ALDH− cells sorted from DU145 and LNCaP-IL6 cells were treated with 25 µM galiellalactone for 24 h. …”

Model validation: autophagy inducers reduce TAU hyperphosphorylation and aggregation in TAU-P301L neurons. by An Verheyen (840523)

“…<b>(G, H)</b> AlphaLISA results reveal that trehalose significantly reduces hTAU10 (P<0,001) and AT8 TAU aggregation levels <i>versus</i> control (P = 0,006 at 31,5 mM and P = 0,014 at 125 mM). <b>(I, J)</b> Only at 125 mM of trehalose, both phosphorylated TAU (P<0,001, I) and total TAU levels (P<0,001, J) are decreased. …”