Effect of ABCG2 overexpression on the expression of SLC transporter genes and MPP, glucose and glutamine transport. by Maricla Galetti (475203)

“…<p>Down-regulation of SLC transporter expression (SLC22A1, SLC22A3, SLC2A1, SLC38A2, SLC3A2, SLC7A5, and SLC7A6) in HEK293/R2 cells versus HEK293 was evaluated by PCR drug transporter array (A). …”

Image_2_Global Characterization of Peripheral B Cells in Parkinson’s Disease by Single-Cell RNA and BCR Sequencing.jpeg by Pingping Wang (1485592)

“…Finally, we found a marked clonal expanded memory B cell population in PD patients, up-regulating both MHC II genes (HLA-DRB5, HLA-DQA2 and HLA-DPB1) and transcription factor activator protein 1 (AP-1), suggesting that the antigen presentation capacity of B cells was enhanced and B cells were activated in PD patients. …”

Table_2_Global Characterization of Peripheral B Cells in Parkinson’s Disease by Single-Cell RNA and BCR Sequencing.xlsx by Pingping Wang (1485592)

“…Finally, we found a marked clonal expanded memory B cell population in PD patients, up-regulating both MHC II genes (HLA-DRB5, HLA-DQA2 and HLA-DPB1) and transcription factor activator protein 1 (AP-1), suggesting that the antigen presentation capacity of B cells was enhanced and B cells were activated in PD patients. …”

Image_1_Global Characterization of Peripheral B Cells in Parkinson’s Disease by Single-Cell RNA and BCR Sequencing.jpeg by Pingping Wang (1485592)

“…Finally, we found a marked clonal expanded memory B cell population in PD patients, up-regulating both MHC II genes (HLA-DRB5, HLA-DQA2 and HLA-DPB1) and transcription factor activator protein 1 (AP-1), suggesting that the antigen presentation capacity of B cells was enhanced and B cells were activated in PD patients. …”

Silencing BRE Expression in Human Umbilical Cord Perivascular (HUCPV) Progenitor Cells Accelerates Osteogenic and Chondrogenic Differentiation by Elve Chen (392737)

“…<i>BRE</i>-silencing negatively regulated <i>OCT4</i>, <i>FGF5</i> and <i>FOXO1A</i>. <i>BRE</i>-silencing also altered the expression of epigenetic genes and components of the TGF-β/BMP and FGF signaling pathways which are crucially involved in maintaining stem cell self-renewal. …”

Table_1_Global Characterization of Peripheral B Cells in Parkinson’s Disease by Single-Cell RNA and BCR Sequencing.xlsx by Pingping Wang (1485592)

“…Finally, we found a marked clonal expanded memory B cell population in PD patients, up-regulating both MHC II genes (HLA-DRB5, HLA-DQA2 and HLA-DPB1) and transcription factor activator protein 1 (AP-1), suggesting that the antigen presentation capacity of B cells was enhanced and B cells were activated in PD patients. …”

IPA analysis reveals oxidative phosphorylation pathway. by Claudia Kruger (141215)

“…HF <i>Acads+/+</i> mice, we found significantly decreased expression of ATP synthase genes in mitochondrial complex 5 (top panel), consistent with a state of decreased energy availability.…”

Monitoring vegetation coverage in Tongren from 2000 to 2016 based on Landsat7 ETM+ and Landsat8 by HUAIPENG LIU (5837144)

“…Experimental results showed that: (1) the different time phase partial image substitution method could reduce the influence of clouds on vegetation extraction; (2) in Tongren, the vegetation coverage area was decreased from 17,300.1 km2 to 17,224.8 km2 (i.e. decreased by 75.3 km2); (3) the areas of grade I and V increased by 0.42% and 15.08%, respectively, whereas the areas of grade II, III and IV decreased by 3.15%, 6.98% and 5.37%, respectively, which indicates that most of the area containing lower amount of vegetation gradually altered into an area containing a higher coverage of vegetation, whereas a few areas became bare land; and (4) the vegetation areas decreased due to expansion of cities and construction of dams, while vegetation increased due to the cultivation of crops and trees. …”

YorkU.grassland-disturbed.oct42016 by Jesse Jauhal (3115965)

“…Data was collected at 2m intervals along the transect and noted only the trees that were 0.5m away from the transect. If a tree was present in a 0.5m distance, then a canopy cover percentage was recorded, if not, zero was recorded. …”

Relation between Intramolecular NH···S Hydrogen Bonds and Coordination Number in Mercury(II) Complexes with Carbamoylbenzenethiol Derivatives by Masahiro Kato (55602)

“…Conversely, the ¹⁹⁹Hg NMR spectra in <b>5</b> show a high-field shift with a decrease in the flow of electrons to mercury(II) from the sulfur atom due to the intramolecular NH···S hydrogen bond.…”

Relation between Intramolecular NH···S Hydrogen Bonds and Coordination Number in Mercury(II) Complexes with Carbamoylbenzenethiol Derivatives by Masahiro Kato (55602)

“…Conversely, the ¹⁹⁹Hg NMR spectra in <b>5</b> show a high-field shift with a decrease in the flow of electrons to mercury(II) from the sulfur atom due to the intramolecular NH···S hydrogen bond.…”

Influence of the methanol supply on DNase1 expression. by Jan-Ole Krischek (21213122)

“…<p>(A) Raising MeOH above 0.5% (v/v) in the expression medium increases preαMF-mDNase1 production with an optimum at 5% MeOH and 24 °C (p =  0.0059) and even more at 2.5% and 28 °C (p =  0.0441) as determined by HCA of SN. …”

Relation between Intramolecular NH···S Hydrogen Bonds and Coordination Number in Mercury(II) Complexes with Carbamoylbenzenethiol Derivatives by Masahiro Kato (55602)

“…Conversely, the ¹⁹⁹Hg NMR spectra in <b>5</b> show a high-field shift with a decrease in the flow of electrons to mercury(II) from the sulfur atom due to the intramolecular NH···S hydrogen bond.…”

Relation between Intramolecular NH···S Hydrogen Bonds and Coordination Number in Mercury(II) Complexes with Carbamoylbenzenethiol Derivatives by Masahiro Kato (55602)

“…Conversely, the ¹⁹⁹Hg NMR spectra in <b>5</b> show a high-field shift with a decrease in the flow of electrons to mercury(II) from the sulfur atom due to the intramolecular NH···S hydrogen bond.…”

Modulation of gamma oscillations by speed in CA1 is rapid. by Caleb Kemere (452950)

“…Periods of decreasing speed are marked by an increase in slow gamma power (blue bars) and a concomitant decrease in fast gamma power (red bars). …”

Cell stress, the UPR and <i>headcase</i>. by Panagiotis Giannios (10113763)

“…Synchronous overexpression of a <i>UAS-hdc</i> with an RNAi against Xbp1 <b>(F)</b> and PEK <b>(J)</b> results in the decrease in the observed apoptotic death, compared to the UPR disruption after knockdown of its mediators (<i>Xbp1</i> <b>(D)</b> and <i>PERK</i> <b>(H)</b>) alone. …”

Mouse survival curves after carbon nanomaterial injection. by Alan C. L. Tang (175971)

“…SWCNTs and MWCNTs had the highest toxicity, which was dose dependent, decreasing as the dose of the carbon nanomaterials decreased. …”

Image1_Novel multitarget analgesic candidate SZV-1287 demonstrates potential disease-modifying effects in the monoiodoacetate-induced osteoarthritis mouse model.TIF by Ádám István Horváth (15443678)

“…Introduction<p>Monoiodoacetate (MIA)-induced osteoarthritis (OA) is the most commonly used rodent model for testing anti-OA drug candidates. Herein, we investigated the effects of our patented multitarget drug candidate SZV-1287 (3-(4,5-diphenyl-1,3-oxazol-2-yl) propanal oxime) that is currently under clinical development for neuropathic pain and characterized the mouse model through complex functional, in vivo imaging, and morphological techniques.…”

Table1_Novel multitarget analgesic candidate SZV-1287 demonstrates potential disease-modifying effects in the monoiodoacetate-induced osteoarthritis mouse model.docx by Ádám István Horváth (15443678)

“…Introduction<p>Monoiodoacetate (MIA)-induced osteoarthritis (OA) is the most commonly used rodent model for testing anti-OA drug candidates. Herein, we investigated the effects of our patented multitarget drug candidate SZV-1287 (3-(4,5-diphenyl-1,3-oxazol-2-yl) propanal oxime) that is currently under clinical development for neuropathic pain and characterized the mouse model through complex functional, in vivo imaging, and morphological techniques.…”

Image3_Novel multitarget analgesic candidate SZV-1287 demonstrates potential disease-modifying effects in the monoiodoacetate-induced osteoarthritis mouse model.TIF by Ádám István Horváth (15443678)

“…Introduction<p>Monoiodoacetate (MIA)-induced osteoarthritis (OA) is the most commonly used rodent model for testing anti-OA drug candidates. Herein, we investigated the effects of our patented multitarget drug candidate SZV-1287 (3-(4,5-diphenyl-1,3-oxazol-2-yl) propanal oxime) that is currently under clinical development for neuropathic pain and characterized the mouse model through complex functional, in vivo imaging, and morphological techniques.…”