Regional contemporary (1990–1999 mean) precipitation and JULES inundation fraction over the Amazon basin. by Nic Gedney (19762301)

hESCs-CM inhibited cell cycle progression of cancer cells and initiated a pro-apoptotic program. by Shufeng Zhou (398572)

ArxE mice have almost complete loss of α-cell fate by P14 with a concomitant decrease in total endocrine mass, but no change in β- and δ-cell mass. by Crystal L. Wilcox (421799)

Effects of intracellular treatment with 5- or 40-nm AuNPs on AP properties in hippocampal CA1 neurons. by Seungmoon Jung (534987)

“…<p>(A) AuNPs of both sizes significantly decreased the latency to the first AP. The 40-nm AuNPs significantly reduced the AP threshold (B) and AP duration (C). …”

Open data. by Larissa Brazolotto Ferreira (17671168)

Subjects:

Addressing a Trapped High-Energy Water: Design and Synthesis of Highly Potent Pyrimidoindole-Based Glycogen Synthase Kinase-3β Inhibitors by Stanislav Andreev (11067165)

“…Surprisingly, our results demonstrate that this high-energy water was not displaced by our potent inhibitor (<i>S</i>)-3-(3-((7-ethynyl-9<i>H</i>-pyrimido­[4,5-<i>b</i>]­indol-4-yl)­(methyl)­amino)­piperidin-1-yl)­propanenitrile (<b>(<i>S</i>)</b>-<b>15</b>, IC₅₀ value of 6 nM). …”

Addressing a Trapped High-Energy Water: Design and Synthesis of Highly Potent Pyrimidoindole-Based Glycogen Synthase Kinase-3β Inhibitors by Stanislav Andreev (11067165)

“…Surprisingly, our results demonstrate that this high-energy water was not displaced by our potent inhibitor (<i>S</i>)-3-(3-((7-ethynyl-9<i>H</i>-pyrimido­[4,5-<i>b</i>]­indol-4-yl)­(methyl)­amino)­piperidin-1-yl)­propanenitrile (<b>(<i>S</i>)</b>-<b>15</b>, IC₅₀ value of 6 nM). …”

hCDC-derived exosomes significantly decrease cardiomyocyte programed cell death and cause a trend toward increased proliferation of cardiomyocytes <i>in vitro</i> at one week in cu... by Jennifer K. Lang (344441)

Predictive values of IC₅₀ in mM (FFAs) for vanadium compounds and <i>in vivo</i> observations IC₅₀ in mM (FFAs) and decreasing blood glucose level. by Elena V. Fedorova (603922)

Correction of decreased TRACP 5b concentrations resulting from high-UA individuals compared to healthy subjects. by Zhi-Qi Wu (847506)

Top 50 genes whose expression is most decreased in PN11 <i>Klf5</i>CN compared with the WT corneas. by Doreswamy Kenchegowda (135193)

Top 50 genes whose expression is most decreased in PN56 <i>Klf5</i>CN compared with the WT corneas. by Doreswamy Kenchegowda (135193)

Susceptibility of half knockout strains to CYP51 inhibitors (EC50, μM): compounds with decreased activity on HKO + CYP strains. by Laura-Isobel McCall (222498)

Bortezomib in combination with the PLK1 inhibitor BI 2536 induces a significant downregulation of the total levels and phosphorylation of Bcr-Abl, a decrease of downstream phosphor... by Octavian Bucur (470431)

“…K562 and K562-R cells were treated with 9nM bortezomib and 8nM BI 2536 for 60h, followed by the detection of Bcr-Abl and phosphorylated STAT5. …”

Changes in differential chlorophyll fluorescence curves modulated reflection at 820 nm. by Yousra El-Mejjaouy (15877635)

Decreased peritumoral myofibroblasts in the MC38 S.C. tumors of <i>S100a4-Cre; Ext1</i>^<i>f/f</i> mice. by Ayumi Niwa (6256790)

KDM6A mRNA expression is decreased in PTFE mice. by Simon Lebek (9756148)

Effect of MA-5 on sIBM myoblasts. by Yoshitsugu Oikawa (9721356)

Acute exercise decreased plasma insulin and glucose. by Mirian A. Kurauti (3146271)

Body weight, femoral length and <i>Notch3</i> transcripts of 8.5–9 week old male <i>Notch3</i>^{<i>em1Ecan</i>} mutant mice (gray bars) and littermate controls (white bars)... by Ernesto Canalis (516050)