Human MADD fibroblast cells display similar mitochondrial defects as <i>xav</i> mutants. by Yuanquan Song (238595)

“…</b> Oxygen consumption was measured in intact control and MADD Patient 1 fibroblasts under basal conditions, following the addition of the mitochondrial ATP synthase inhibitor oligomycin (0.5 µg/ml), in the presence of the uncoupler CICCP (3 µM) to maximally stimulate respiration and following the addition of complex I inhibitor rotenone (100 nM) to assess residual non-mitochondrial oxygen consumption. …”

Structure–Kinetics Correlations in Isostructural Crystals of α‑(<i>ortho</i>-Tolyl)-acetophenones: Pinning Down Electronic Effects Using Laser-Flash Photolysis in the Solid State... by Anoklase J.-L. Ayitou (1906648)

“…Notably, the rate for δ-hydrogen atom transfer of <b>1a</b> (2.7 × 10⁷ s^–1) in the crystalline phase is 18-fold larger than that of <b>1b</b> (1.5 × 10⁶ s^–1). With nearly identical molecular and crystal structures, this decrease in the rate of δ-hydrogen abstraction can be assigned unambiguously to an electronic effect by the <i>para-</i>methyl group in <b>1b</b>, which increases the contribution of the ³π,π* configuration relative to the reactive ³n,π* configuration in the lowest triplet excited state. …”

Effect of EGFR-induced VEGF on phosphorylation of VEGFR2, AKT and ERK. by Lilian Saryeddine (3328554)

“…<b>(C)</b> Similarly, phosphorylation of AKT and ERK, but not p38, was inhibited when cells were pre-incubated for 1h with 2μg/ml anti-VEGFR2 antibodies. <b>(D)</b> siRNA (20nM) against VEGFR2, left after transfection for 72h, caused a decrease in the phosphorylation levels of AKT and ERK, but not p38. …”

Chemical probing techniques were employed to determine Ysr170 secondary structure and interactions with Hfq. by Nan Li (155066)

“…(B) Summary of probing data overlaid on the secondary structure. Ysr170 (0.5 μM) was folded in 1xHMK buffer containing 1.5 μM of Hfq at 37°C for 10 min. …”

Activity and binding assays of amidase mutants. by Sebastian Zoll (366396)

“…Lysis of peptidoglycan was measured as the decrease in optical density at 578 nm. (C) Complementation of the <i>S. aureus</i> SA113Δ<i>atlA</i> mutant. …”

<i>Ras</i> cells show myeloid differentiation upon cytarabine treatment. by Mona Meyer (257592)

“…Control and <i>Ras</i> cells were treated with either 100 nM cytarabine or 0.5 mM caffeine, respectively, or with both components simultaneously for 24 hours, washed and cultured for additional 48 hours in the absence of cytarabine. …”

Secondary screening and ‘hit’ validation. by Ilona Tkachyova (343715)

“…Distinct decrease in <i>NDST1</i> expression was observed for 2x IC₅₀ SAHA treatment. …”

DataSheet1_The Efficacy and Mid-term Durability of Urethral Sphincter Injections of Platelet-Rich Plasma in Treatment of Female Stress Urinary Incontinence.docx by Ching-Hsiang Chiang (12057068)

“…The follow-up date was 12 months after the fourth PRP treatment.</p><p>Results: The mean age was 61.7 ± 15.3 years. The overall success rate was 50% with the post-treatment mean GRA of 1.5 ± 1.1. …”

mTORC1 inhibits Runx2 expression by activating Notch signaling in preosteoblasts. by Bin Huang (331329)

“…<p>(A) Control (C) and Δ<i>Tsc1</i> (Δ) primary calvarial cells were treated with vehicle (V) or 0.1 nM rapamycin (R) for 24 hours and then underwent immunoblotting to detect Runx2. …”

9.2.27PE in combination with ABT-737 induces apoptosis in melanoma cells. by Karianne Risberg (207221)

“…<p>(A) FEMX cells and Melmet-5 cells were treated with 9.2.27PE (100 ng/ml)±ABT-737 (10 µM) for 24 h. …”

Studies of changes in concentration under different perturbation scenarios. by Xu Gu (276054)

Size effects on dislocation starvation in Cu nanopillars: a molecular dynamic simulations study by G. Sainath (17069218)

“…In this context, atomistic simulations have been performed on the compression of <110> Cu nanopillars with size (d) ranging from 5 to 21.5 nm. Molecular dynamics (MD) simulation results indicate that the nanopillars deform by the slip of extended dislocations and exhibit dislocation starvation mainly at small sizes (<20 nm). …”

METHOD DEVELOPMENT AND VALIDATION FOR THE FLUOROQUINOLONES DETERMINATION BY STABILIZED SILVER NANOPARTICLES by Luiza D. de M. Moraes (10380225)

Effects of visceral adipose tissue reduction on CVD risk factors independent of weight loss: The Look AHEAD study by Anawin Sanguankeo (766655)

Plasma Neutrophil Elastase and Elafin Imbalance Is Associated with Acute Respiratory Distress Syndrome (ARDS) Development by Zhaoxi Wang (71954)

“…Although the controls had elevated plasma PI3 and HNE, their HNE/PI3 ratio (mean = 6.5; 95% CI, 4.9–8.8) was not significantly different from the healthy individuals (mean = 3.9; 95% CI, 2.7–5.9). …”

Analysis of LRRK2 effect on DRD2 total protein level. by Mauro Rassu (4068670)

“…The data represent the mean ± SD.</p>…”

Enhanced photocatalytic activity of N, P, co-doped carbon quantum dots: an insight from experimental and computational approach - data by HJ Yashwanth (19695421)

FULL-THICKNESS ENDOSCOPIC GASTRIC RESECTION USING A STAPLER AND GASTROSTOMY: A FEASIBILITY STUDY by André M. WADA (5670695)

“…The overall complication rate was 7.7%. After a mean period of 7.4±5.3 months(1-30), mean excess weight loss was 71.3±27.1% (10.2-155.4). …”

Decay rate comparison for Pavlovian experiment. by Weston Fleming (10924744)

“…Mean tonic firing rates prior to presentations of unexpected reward, where tonic firing rates are calculated as the mean firing rate over a 1 s period prior to reward presentation (inferred spikes tonic firing rate median = 5.6 Hz, Q1 = 5.1 Hz, Q3 = 6.0 Hz, for low gamma; median = 5.7 Hz, Q1 = 5.3 Hz, Q3 = 6.0 Hz for median gamma; median = 5.9 Hz, Q1 = 5.3 Hz, Q3 = 6.1 Hz for high gamma; electrophysiology tonic firing rate median = 5.6 Hz, Q1 = 4.3 Hz, Q3 = 7.5 Hz). …”

Roscovitine inhibition of MARCKS phosphorylation at S25 in different functional states of retinal cells. by Andrea Toledo (407433)

“…<p>E4.5 and E8 retinal cells were treated with the Cdk inhibitor roscovitine after different cell culture protocols, and the relative phosphorylation of MARCKS at S25 assayed by Western-blot. …”