Quantifying the Human Cost of Global Warming (Code) by Timothy M. Lenton (15312245)

“…Reducing global warming from 2.7 to 1.5 °C results in a ~5-fold decrease in the population exposed to unprecedented heat (MAT ≥29 °C). …”

<i>F. novicida</i> deletion mutants of a putative transglutaminase are severely attenuated in virulence and growth. by Madeleine G. Moule (243057)

“…The difference between the mean number of CFUs of wild-type and FTN_0869 has decreased at every timepoint, with only a 2.9-fold increase in wild-type bacteria compared to FTN_0869 bacteria at 24 hours, 6-fold more bacteria in U112 infected flies at 48 hours, and only 4-fold more U112 bacteria than FTN_0869 bacteria at 72 hours. …”

A Randomized, Placebo Controlled, Double Masked Phase IB Study Evaluating the Safety and Antiviral Activity of Aprepitant, a Neurokinin-1 Receptor Antagonist in HIV-1 Infected Adul... by Pablo Tebas (27720)

“…<div><h3>Background</h3><p>Neurokinin-1 receptor (NK1R) antagonists have anti-HIV activity in monocyte-derived macrophages, decrease CCR5 expression and improve natural killer cell function <em>ex vivo</em>. …”

Med promotes bone regeneration at the drill hole site in Ovx osteopenic rats. by Manisha Dixit (777718)

“…^c<i>P</i>< 0.001 compjared with Sham + vehicle group; ^b<i>P</i>< 0.01compared with Sham + vehicle group; ^a<i>P</i>< 0.05compared with Sham + vehicle group; ^z<i>P</i>< 0.001 compared with Ovx + vehicle group; ^y<i>P</i>< 0.01 compared with Ovx + vehicle group; ^x<i>P</i>< 0.05 compared with Ovx + vehicle group; ^r<i>P</i>< 0.001 compared with Ovx + 0.5mg/kg med group; ^p<i>P</i>< 0.05 compared with Ovx + 0.5mg/kg med group; ^l<i>P</i>< 0.001 compared with Ovx + 1.0mg/kg med group; ^k<i>P</i>< 0.01 compared with Ovx + 1.0mg/kg med group; ^j<i>P</i>< 0.05 compared with Ovx + 1.0mg/kg med group; ^o<i>P</i>< 0.001 compared with Ovx + 5.0mg/kg med group; ^m<i>P</i>< 0.05 compared with Ovx + 5.0mg/kg med group.…”

Down-regulation of the <i>cwp</i> genes in cells expressing the <i>luciferase</i> gene with a nonsense mutation. by Yi-Hsiu Chen (375991)

“…(B) Nonsense mutation leads to a decrease of luciferase activity. After stable transfection with the pPT5 and pPT5m constructs, luciferase activity was measured in vegetative cells. …”

Clinical and epidemiological study in patients with primary open-angle glaucoma by Luciana dos Mares Guia Ribeiro (4985879)

“…We used statistical analysis, and the results are presented by mean, standard deviation and percentiles 25, 50 and 75. …”

IP3Rs localization and function. by Ilanit Itzhaki (225708)

“…(<b>E–F</b>) Dose-response curves displaying the effects of 2-APB (0.1, 0.5, 1, 2, 5 and 10 µM) (E) and U73122 (0.5, 1, 2 and 3 µM) (F) on whole-cell [Ca²⁺]_i transients amplitude (displayed as the relative decrease (%) versus baseline values). …”

Subcutaneous transplantation of L23 cells in the ear induce fast rejection and reduced proliferative response of draining lymph node cells. A: by Lilli Kraus (302769)

“…Lymphocytes were (re-)stimulated with 2×10³ irradiated L23 cells for 5 days. Comparison of proliferative response showed a decrease of ³H thymidin incorporation in draining lymph nodes. …”

Assessment of oscillatory potential (OP) amplitude profiles. by Jake Bedore (777372)

“…Quantification of summed OP amplitude for the four OPs measured over the four largest stimulus strengths (0.63–25 cd˖s /m²) under scotopic conditions measured shows a significant decrease in VAChT^{Six3-Cre-flox/flox} retinas (open circles) relative to littermate controls (VAChT^flox/flox, closed squares) at (I) 5 (n = 7 VAChT^{Six3-Cre-flox/flox} and n = 12 littermate control) and (J) 12 months of age (n = 5 VAChT^{Six3-Cre-flox/flox} and n = 5 littermate control). …”

Effect of convergence criterion on overall solution accuracy. by Christian Schlinkmann (9585315)

“…At 6% error a value of 1.0×10⁻⁵ already gives a good approximation of the final solution, with the overall error stabilizing at 3.7% for a value of 1.0×10⁻⁷. b) Mean relative error of the displacements as a function of simulation time, using no additional levels of detail and 1.0×10⁻⁷ as convergence criterion. c) Relative error of the maximum displacement in an analytical example consisting of a steel beam with a compressive load applied parallel to the longest axis. …”

Quantification of ICAM-1 adhesion. by Jaap D. van Buul (5650009)

“…Experiment is done three times in duplicate. Data are mean ± SEM. *p<0.01.</p>…”

Strong interdependence generates communities that are robust to variation in initial conditions. by Sylvie Estrela (156401)

“…An increment in initial segregation of 0.1 means a 5% increase (or decrease) in the number of cells of species A (or species B) inoculated in each microcolony. …”

Proliferation of HBO-treated cells. by Jennifer Schulze (2502799)

“…Both NIH3T3 and NIH3T3/BDNF fibroblasts show a highly significantly increased cell number compared to the control cells (normoxic and normobaric conditions (NOR), green inverted triangle and line) after five consecutive HBO treatments. By contrast, the proliferation of MSCs started to decrease after five consecutive HBO treatments with 2.0 bar until the end of ten treatments in comparison to NOR. …”

Oligodendrocyte depletion with DT results in axonal damage but does not affect cortical neuronal density. by Aniket Ghosh (212168)

“…Quantifications represent mean and SEM (n = 8 MOGi-Cre/iDTR mice treated with DT, 5 DT-treated MOGi-Cre animals as control (middle panel) and 3 MOGi-Cre/iDTR animals treated with PBS, ns: not significant).…”

FIGURE 3 from Cancer-associated Fibroblast–specific Expression of the Matricellular Protein CCN1 Coordinates Neovascularization and Stroma Deposition in Melanoma Metastasis by James Hutchenreuther (18062436)

“…Representative images shown; Graph shows mean area of collagen, detected using trichrome stain, present in stroma images ± SD; Student <i>t</i> test; <i>n</i>  =  3). α-SMA–expressing myofibroblasts (<b>B</b>) and YAP-positive nuclei (<b>C</b>) are present in both wild-type and CCN1-deficient stroma (Representative images shown; Graphs represent mean α-SMA positive cells ± SD; one-way ANOVA; <i>n</i>  =  5). …”

Fig 3 - by Nasser Semmo (76848)

“…The decrease in mean FSS score from baseline (Day 1) to Day 28, Day 84 and 12 weeks post-treatment (Day 168) is shown for (d) the sdITT population and (e) the mITT population. ° = outlier (value maximum 1.5 to 3 fold box length); FSS = fatigue severity scale, mITT = modified intention to treat; sdITT = scaled down intention to treat; V = study visit.…”

EFFECTS OF PHYSICAL TRAINING ON THE MYOCARDIUM OF FEMALE LDL KNOCKOUT OVARIECTOMIZED MICE by Ledimar Brianezi (4695028)

“…We analyzed the mean nuclear volume parameters, the cross sectional area of the myocytes, the apparent density of the capillaries, interstitium, myocytes and collagen fibers. …”

Age-dependent ASM at <i>MCHR1</i>. by Stefanie Stepanow (219536)

“…The GT allele shows a mean methylation of 20.7±5.1% and the AC allele is 26.5±4.4% methylated. …”

S9 Fig - by Anil Pant (10074299)

“…HFFs were infected with VACV at an MOI of 2 in the presence or absence of 50 μM PD0325901 for 24 h. A plaque assay was performed to measure virus titers. …”

CNF1 effect on proteins involved in mitochondrial dynamics in cortex tissues from pathological mice. by Sara Travaglione (326283)