Global level of 5mC and of H3K9ac in ovine SCNT embryos. حسب Parisa Nadri (13132252)

Bidirectional Optical Control of Proton Motive Force in Escherichia coli Using Microbial Rhodopsins حسب Kotaro Nakanishi (3389300)

"…Tethered cell experiments revealed that, upon illumination, the torque of the flagellar motor decreased to nearly zero (28 pN nm) with <i>Rm</i>XeR, while it increased to 1170 pN nm with AR3. …"

Bidirectional Optical Control of Proton Motive Force in Escherichia coli Using Microbial Rhodopsins حسب Kotaro Nakanishi (3389300)

"…Tethered cell experiments revealed that, upon illumination, the torque of the flagellar motor decreased to nearly zero (28 pN nm) with <i>Rm</i>XeR, while it increased to 1170 pN nm with AR3. …"

Bidirectional Optical Control of Proton Motive Force in Escherichia coli Using Microbial Rhodopsins حسب Kotaro Nakanishi (3389300)

"…Tethered cell experiments revealed that, upon illumination, the torque of the flagellar motor decreased to nearly zero (28 pN nm) with <i>Rm</i>XeR, while it increased to 1170 pN nm with AR3. …"

Bidirectional Optical Control of Proton Motive Force in Escherichia coli Using Microbial Rhodopsins حسب Kotaro Nakanishi (3389300)

"…Tethered cell experiments revealed that, upon illumination, the torque of the flagellar motor decreased to nearly zero (28 pN nm) with <i>Rm</i>XeR, while it increased to 1170 pN nm with AR3. …"

Discovery of the Triazolo[1,5‑<i>a</i>]Pyrimidine-Based Derivative WS-898 as a Highly Efficacious and Orally Bioavailable ABCB1 Inhibitor Capable of Overcoming Multidrug Resistance... حسب Shuai Wang (109515)

"…Here, we reported our medicinal chemistry efforts that led to the discovery of the triazolo­[1,5-<i>a</i>]­pyrimidine derivative <b>WS-898</b> as a highly effective ABCB1 inhibitor capable of reversing paclitaxel (PTX) resistance in drug-resistant SW620/Ad300, KB-C2, and HEK293/ABCB1 cells (IC₅₀ = 5.0, 3.67, and 3.68 nM, respectively), more potent than verapamil and zosuquidar. …"

Discovery of the Triazolo[1,5‑<i>a</i>]Pyrimidine-Based Derivative WS-898 as a Highly Efficacious and Orally Bioavailable ABCB1 Inhibitor Capable of Overcoming Multidrug Resistance... حسب Shuai Wang (109515)

"…Here, we reported our medicinal chemistry efforts that led to the discovery of the triazolo­[1,5-<i>a</i>]­pyrimidine derivative <b>WS-898</b> as a highly effective ABCB1 inhibitor capable of reversing paclitaxel (PTX) resistance in drug-resistant SW620/Ad300, KB-C2, and HEK293/ABCB1 cells (IC₅₀ = 5.0, 3.67, and 3.68 nM, respectively), more potent than verapamil and zosuquidar. …"

Chemical compositions of <i>U.simensis</i> essential oil identified through GC-MS analysis. حسب Bickes Wube (21678222)

Analysis of NIST Monoclonal Antibody Reference Material Glycosylation Using the LC–MS/MS-Based Glycoproteomic Approach حسب Jingfu Zhao (3113421)

"…Here, we applied an LC–MS/MS-based glycoproteomics approach to characterize Fc glycans of an NISTmAb reference material (RM) 8671 (sample B) and a β-1,4-galactosidase-treated NISTmAb (sample A). …"

Study design and settings. حسب Hyun Jin Han (18592254)

"…In contrast a long-term decrease from 1.94 to 1.77 per 100,000 individuals was found in the age-standardized incidence rates. …"

Design and Synthesis of Novel sEH Inhibitors for the Treatment of Inflammatory Bowel Disease حسب Huashen Xu (13987046)

"…Especially, lead compounds <b>A1</b> and <b>A9</b> showed potent inhibitory activities against sEH (<b>A1</b> and <b>A9</b>; hsEH IC₅₀ = 0.1 nM, msEH IC₅₀ = 0.1 nM). …"

Design and Synthesis of Novel sEH Inhibitors for the Treatment of Inflammatory Bowel Disease حسب Huashen Xu (13987046)

"…Especially, lead compounds <b>A1</b> and <b>A9</b> showed potent inhibitory activities against sEH (<b>A1</b> and <b>A9</b>; hsEH IC₅₀ = 0.1 nM, msEH IC₅₀ = 0.1 nM). …"

Design and Synthesis of Novel sEH Inhibitors for the Treatment of Inflammatory Bowel Disease حسب Huashen Xu (13987046)

"…Especially, lead compounds <b>A1</b> and <b>A9</b> showed potent inhibitory activities against sEH (<b>A1</b> and <b>A9</b>; hsEH IC₅₀ = 0.1 nM, msEH IC₅₀ = 0.1 nM). …"

Design and Synthesis of Novel sEH Inhibitors for the Treatment of Inflammatory Bowel Disease حسب Huashen Xu (13987046)

"…Especially, lead compounds <b>A1</b> and <b>A9</b> showed potent inhibitory activities against sEH (<b>A1</b> and <b>A9</b>; hsEH IC₅₀ = 0.1 nM, msEH IC₅₀ = 0.1 nM). …"

The decrease or inhibition of Hsp90 induced REST degradation. حسب Raúl Orozco-Díaz (7067624)

"…(D) The level of REST dramatically reduced in differentiated SH-SY5Y cells treated with GA (1 μM) or PU-H71 (50 nM) at 24 h. …"

Decrease in vRNA in brain during antiretroviral therapy. حسب Sonny R. Elizaldi (9684796)

LSPC treatment decreases neuropathology in prion-infected mice. حسب Heather Bender (363996)

"…(B) In the hippocampus, we observed decreased PrP^Res, GFAP and vacuolation in responder and non-responder mice compared to infected untreated mice. …"

MigC interacts with and decreases the activity of MurD. حسب Jeanette M. Critchlow (21553796)

ALS Variants of Annexin A11’s Proline-Rich Domain Impair Its S100A6-Mediated Fibril Dissolution حسب Aman Shihora (16529668)

"…The ALS variants of A11-PRD showed longer fibrillization half-times and slower dissolution, even though their binding affinities for S100A6 were not significantly affected. These findings indicate a slower fibril-to-monomer exchange for these ALS variants, resulting in a decreased level of S100A6-mediated fibril dissolution. …"

Molecular Simulations Probing the Adsorption and Diffusion of Ammonia, Nitrogen, Hydrogen, and Their Mixtures in Bulk MFI Zeolite and MFI Nanosheets at High Temperature and Pressur... حسب Roshan Patel (10727011)

الموضوعات: