6:2 Chlorinated Polyfluoroalkyl Ether Sulfonate (F-53B) Induces Aging and Parkinson’s Disease-like Disorders in <i>C. elegans</i> at Low Concentrations حسب Hui Li (32376)

الموضوعات:

6:2 Chlorinated Polyfluoroalkyl Ether Sulfonate (F-53B) Induces Aging and Parkinson’s Disease-like Disorders in <i>C. elegans</i> at Low Concentrations حسب Hui Li (32376)

الموضوعات:

6:2 Chlorinated Polyfluoroalkyl Ether Sulfonate (F-53B) Induces Aging and Parkinson’s Disease-like Disorders in <i>C. elegans</i> at Low Concentrations حسب Hui Li (32376)

الموضوعات:

6:2 Chlorinated Polyfluoroalkyl Ether Sulfonate (F-53B) Induces Aging and Parkinson’s Disease-like Disorders in <i>C. elegans</i> at Low Concentrations حسب Hui Li (32376)

الموضوعات:

HAstV-8 (D471S, N512D) spike has decreased or no binding to FcRn compared to wild-type HAstV-8 spike. حسب Catalina Aguilera-Flores (21743843)

HEWL interacts with dissipated oleic acid micelles, and decreases oleic acid cytotoxicity - Fig 1 حسب Qin Huang (49441)

Silencing <i>cullin-1/5</i> decreased mRNA and protein expression of NF-κB dependent cytokines. حسب Attinder Chadha (11414273)

Dynamic of prolactin in pregnant women during pregnancy. حسب Francois Kiemde (5369657)

"…Code: *: <0.05; **: <0.01; ***: <0.001; ****: <0.0001. 30μl of plasma was used to determine the concentration of prolactin in blood (ng/ml). Prolactin levels were compared between multigravidae and primigravidae at each scheduled visits as described in “Method” section and presented as box and whisker plots illustration: top, bottom and middle of box, representing 25^th, 75^th and 50^th percentiles, respectively. …"

Dynamics of cortisol levels measured in pregnant women during pregnancy determined at different ANC visits. حسب Francois Kiemde (5369657)

"…In each case, 30μl of plasma was used to determine for cortisol level in blood (ng/ml). Cortisol levels were compared between multigravidae and primigravidae at each scheduled visits and presented as box and whisker plots illustration: top, bottom and middle of box, representing 25^th, 75^th and 50^th percentiles, respectively. …"

Downregulation of TRIM37 expression exacerbates pathological damage in the MS model. حسب Lai Jiang (2401513)

"…<b>(f, g)</b> TUNEL staining (n = 3) demonstrated a significant increase in the apoptosis rate in the model group compared to the control group. Scale bar = 50 μm. (h) qRT-PCR (n = 6) and <b>(i, j)</b> Western blot (n = 3) both showed a significant decrease in the <i>TRIM37</i> mRNA and protein levels in the LPC-induced MS model compared to the control group. * <i><i>P</i></i> < 0.05, ** <i><i>P</i></i> < 0.01, *** <i><i>P</i></i> < 0.001, **** <i><i>P</i></i> < 0.0001, ns = not significant.…"

Dysregulated alternative splicing in DM1 hiNeurons at 10 DPI. حسب Mougina K. Eltahir (12988153)

Thermodynamic parameters of CR adsorbed onto magnetic Co_0.5Mn_0.5Fe₂O₄ nanoparticles. حسب Xiajun Zhang (3161865)

الموضوعات:

HPLC-MS tentative identification of phenolic metabolites from the defatted extract (DE) of <i>S. malaccense</i> (SM) and <i>S. samarangense</i> (SS) leaves. حسب Fatma A. Moharram (9276104)

الموضوعات:

Structure–Activity Relationship of 3‑Methylcytidine-5′-α,β-methylenediphosphates as CD73 Inhibitors حسب Mirko Scortichini (4007366)

"…We now expand the structure–activity relationship of pyrimidine nucleotides as human CD73 inhibitors. 4-Chloro (MRS4598 <b>16</b>; <i>K</i>_i = 0.673 nM) and 4-iodo (MRS4620 <b>18</b>; <i>K</i>_i = 0.436 nM) substitution of the <i>N</i>⁴-benzyloxy group decreased <i>K</i>_i by ∼20-fold. …"

Structure–Activity Relationship of 3‑Methylcytidine-5′-α,β-methylenediphosphates as CD73 Inhibitors حسب Mirko Scortichini (4007366)

"…We now expand the structure–activity relationship of pyrimidine nucleotides as human CD73 inhibitors. 4-Chloro (MRS4598 <b>16</b>; <i>K</i>_i = 0.673 nM) and 4-iodo (MRS4620 <b>18</b>; <i>K</i>_i = 0.436 nM) substitution of the <i>N</i>⁴-benzyloxy group decreased <i>K</i>_i by ∼20-fold. …"

Structure–Activity Relationship of 3‑Methylcytidine-5′-α,β-methylenediphosphates as CD73 Inhibitors حسب Mirko Scortichini (4007366)

"…We now expand the structure–activity relationship of pyrimidine nucleotides as human CD73 inhibitors. 4-Chloro (MRS4598 <b>16</b>; <i>K</i>_i = 0.673 nM) and 4-iodo (MRS4620 <b>18</b>; <i>K</i>_i = 0.436 nM) substitution of the <i>N</i>⁴-benzyloxy group decreased <i>K</i>_i by ∼20-fold. …"

Analytical sensitivity and reproducibility. حسب Lizhi Yu (12476136)

Depth of coverage and heterogeneity of the mutation loci. x-axis, mutation loci in sample set one or two; y-axis, depth of coverage after UMI consolidation. حسب Lizhi Yu (12476136)

Reference mutations versus background noise across replicates. حسب Lizhi Yu (12476136)

Quantification and accuracy of average VAF. حسب Lizhi Yu (12476136)